| Field | Sense | Antisense |
| siRNA chemical modification | 0 | 4-C- Aminomethyl-2-O-Methylribose |
| siRNA modification types | 0 | 1 |
| Overall number of modifications | 0 | 1 |
| Position of modifications | 0 | 3,21 |
| Modification on sugar or base or phosphate | 0 | Sugar |
| SMILES (Click to view structure & nomenclature) |
- |
COC1COC(CN)(CO)C1O |
| siRNA Sequence | GGCCUUUCACUACUCCUACTT | AGUAGGAGUAGUGAAAGGCCUT |
| siRNA length base-pair | 21 | 22 |
| siRNA name in paper | 3R-7R | 3R-7R |
| Biological activity | 66 percent target mRNA inhibition | |
| Experiment used to check activity | Dual luciferase reporter assay | |
| Melting temperature (oC) | 77.2 | |
| Target gene | Renilla luciferase | |
| siRNA concentration | 33 nM | |
| Cell or Organism used | HeLa cells | |
| Transfection method | Lipofectamine 2000 | |
| Duration after transfection | 48 Hours | |
| Article title | Synthesis, gene silencing, and molecular modeling studies of 4'-C-aminomethyl-2'-O-methyl modified small interfering RNAs |
|
| Reference | 22372696 | |