| ASPsiRNA ID | Pairing of target region (top) and ASP-siRNA (bottom) | Efficacy (mut)(%) | Efficacy (wt) (%) | Diff | Gene | Disease | Mutation | RefSNP | Analysis | Pubmed ID |
|---|---|---|---|---|---|---|---|---|---|---|
| ASPsiRNA ID | Mutant allele/ASP-siRNA | Efficacy for mutant(%) |
Efficacy for wild (%) |
Relative Difference (%) | Gene | Disease | Mutation | RefSNP | Analysis | Pubmed ID |
| aspsirna0241 | GCAAAGAUUGCUGACUACA CGUUUCUAACGACUGAUGU |
75 | 27 | 48 | LRRK2 | Parkinsons disease (PD) | c.6055G>A,p.Gly2019Ser | rs34637584 | 
|
|
| aspsirna0242 | CAAAGAUUGCUGACUACAG GUUUCUAACGACUGAUGUC |
40 | 20 | 20 | LRRK2 | Parkinsons disease (PD) | c.6055G>A,p.Gly2019Ser | rs34637584 |
|
|
| aspsirna0243 | GAAGAUUGCUGACUACAGC CUUCUAACGACUGAUGUCG |
60 | 24 | 36 | LRRK2 | Parkinsons disease (PD) | c.6055G>A,p.Gly2019Ser | rs34637584 |
|
|
| aspsirna0244 | GAGAUUGCUGACUACAGCA CUCUAACGACUGAUGUCGU |
2 | 55 | -53 | LRRK2 | Parkinsons disease (PD) | c.6055G>A,p.Gly2019Ser | rs34637584 |
|
|
| aspsirna0245 | AGAUUGCUGACUACAGCAU UCUAACGACUGAUGUCGUA |
13 | 88 | -75 | LRRK2 | Parkinsons disease (PD) | c.6055G>A,p.Gly2019Ser | rs34637584 |
|
|
| aspsirna0246 | GAUUGCUGACUACAGCAUU CUAACGACUGAUGUCGUAA |
13 | 59 | -46 | LRRK2 | Parkinsons disease (PD) | c.6055G>A,p.Gly2019Ser | rs34637584 |
|
|
| aspsirna0247 | AUUGCUGACUACAGCAUUG UAACGACUGAUGUCGUAAC |
40 | 27 | 13 | LRRK2 | Parkinsons disease (PD) | c.6055G>A,p.Gly2019Ser | rs34637584 |
|
|
| aspsirna0248 | UUGCUGACUACAGCAUUGC AACGACUGAUGUCGUAACG |
30 | 20 | 10 | LRRK2 | Parkinsons disease (PD) | c.6055G>A,p.Gly2019Ser | rs34637584 |
|
|
| aspsirna0249 | UGCUGACUACAGCAUUGCU ACGACUGAUGUCGUAACGA |
55 | 50 | 5 | LRRK2 | Parkinsons disease (PD) | c.6055G>A,p.Gly2019Ser | rs34637584 |
|
|
| aspsirna0250 | GCUGACUACAGCAUUGCUC CGACUGAUGUCGUAACGAG |
75 | 30 | 45 | LRRK2 | Parkinsons disease (PD) | c.6055G>A,p.Gly2019Ser | rs34637584 |
|
|
| aspsirna0251 | CUGACUACAGCAUUGCUCA GACUGAUGUCGUAACGAGU |
60 | 40 | 20 | LRRK2 | Parkinsons disease (PD) | c.6055G>A,p.Gly2019Ser | rs34637584 |
|
|
| aspsirna0252 | UGACUACAGCAUUGCUCAG ACUGAUGUCGUAACGAGUC |
80 | 65 | 15 | LRRK2 | Parkinsons disease (PD) | c.6055G>A,p.Gly2019Ser | rs34637584 |
|
|
| aspsirna0253 | GACUACAGCAUUGCUCAGU CUGAUGUCGUAACGAGUCA |
60 | 45 | 15 | LRRK2 | Parkinsons disease (PD) | c.6055G>A,p.Gly2019Ser | rs34637584 |
|
|
| aspsirna0254 | ACUACAGCAUUGCUCAGUA UGAUGUCGUAACGAGUCAU |
77 | 65 | 12 | LRRK2 | Parkinsons disease (PD) | c.6055G>A,p.Gly2019Ser | rs34637584 |
|
|
| aspsirna0255 | CUACAGCAUUGCUCAGUAC GAUGUCGUAACGAGUCAUG |
80 | 60 | 20 | LRRK2 | Parkinsons disease (PD) | c.6055G>A,p.Gly2019Ser | rs34637584 |
|
|
| aspsirna0256 | UACAGCAUUGCUCAGUACU AUGUCGUAACGAGUCAUGA |
50 | 40 | 10 | LRRK2 | Parkinsons disease (PD) | c.6055G>A,p.Gly2019Ser | rs34637584 |
|
|
| aspsirna0257 | CUGAUUACAGCAUUGCUCA GACUAAUGUCGUAACGAGU |
36 | 10 | 26 | LRRK2 | Parkinsons disease (PD) | c.6055G>A,p.Gly2019Ser | rs34637584 |
|
|
| aspsirna0258 | CUGAGUACAGCAUUGCUCA GACUCAUGUCGUAACGAGU |
88 | 73 | 15 | LRRK2 | Parkinsons disease (PD) | c.6055G>A,p.Gly2019Ser | rs34637584 |
|
|
| aspsirna0259 | ACUACAGCACUGCUCAGUA UGAUGUCGUGACGAGUCAU |
76 | 45 | 31 | LRRK2 | Parkinsons disease (PD) | c.6055G>A,p.Gly2019Ser | rs34637584 |
|
|
| aspsirna0260 | ACUACAGCAGUGCUCAGUA UGAUGUCGUCACGAGUCAU |
88 | 25 | 63 | LRRK2 | Parkinsons disease (PD) | c.6055G>A,p.Gly2019Ser | rs34637584 |
|
|
| aspsirna0261 | ACUAUAGCAUUGCUCAGUA UGAUAUCGUAACGAGUCAU |
62 | 24 | 38 | LRRK2 | Parkinsons disease (PD) | c.6055G>A,p.Gly2019Ser | rs34637584 |
|
|
| aspsirna0262 | ACUAGAGCAUUGCUCAGUA UGAUCUCGUAACGAGUCAU |
67 | 49 | 18 | LRRK2 | Parkinsons disease (PD) | c.6055G>A,p.Gly2019Ser | rs34637584 |
|
|
| aspsirna0263 | CUAUAGCAUUGCUCAGUAC GAUAUCGUAACGAGUCAUG |
50 | 21 | 29 | LRRK2 | Parkinsons disease (PD) | c.6055G>A,p.Gly2019Ser | rs34637584 |
|
|
| aspsirna0264 | CUAGAGCAUUGCUCAGUAC GAUCUCGUAACGAGUCAUG |
30 | 25 | 5 | LRRK2 | Parkinsons disease (PD) | c.6055G>A,p.Gly2019Ser | rs34637584 |
|
|
| aspsirna0265 | CUGACUACAGUAUUGCUCA GACUGAUGUCAUAACGAGU |
72 | 60 | 12 | LRRK2 | Parkinsons disease (PD) | c.6055G>A,p.Gly2019Ser | rs34637584 |
|
|
| aspsirna0266 | CUGACUACAGGAUUGCUCA GACUGAUGUCCUAACGAGU |
46 | 65 | -19 | LRRK2 | Parkinsons disease (PD) | c.6055G>A,p.Gly2019Ser | rs34637584 |
|
|
| aspsirna0267 | CUGACUACAGAAUUGCUCA GACUGAUGUCUUAACGAGU |
85 | 55 | 30 | LRRK2 | Parkinsons disease (PD) | c.6055G>A,p.Gly2019Ser | rs34637584 |
|
|
| aspsirna0268 | CUGACUACAACAUUGCUCA GACUGAUGUUGUAACGAGU |
70 | 56 | 14 | LRRK2 | Parkinsons disease (PD) | c.6055G>A,p.Gly2019Ser | rs34637584 |
|
|
| aspsirna0269 | CUGACUACAUCAUUGCUCA GACUGAUGUAGUAACGAGU |
88 | 60 | 28 | LRRK2 | Parkinsons disease (PD) | c.6055G>A,p.Gly2019Ser | rs34637584 |
|
|
| aspsirna0270 | CUGACUACACCAUUGCUCA GACUGAUGUGGUAACGAGU |
7 | 16 | -9 | LRRK2 | Parkinsons disease (PD) | c.6055G>A,p.Gly2019Ser | rs34637584 |
|
|
| aspsirna0271 | GAGAUUGCUGGCUACAGCA CUCUAACGACCGAUGUCGU |
92 | 15 | 77 | LRRK2 | Parkinsons disease (PD) | c.6055G>A,p.Gly2019Ser | rs34637584 |
|
|
| aspsirna0272 | GAGAUUGCUAACUACAGCA CUCUAACGAUUGAUGUCGU |
75 | 5 | 70 | LRRK2 | Parkinsons disease (PD) | c.6055G>A,p.Gly2019Ser | rs34637584 |
|
|
| aspsirna0273 | GAGAUUGCGGACUACAGCA CUCUAACGCCUGAUGUCGU |
55 | 30 | 25 | LRRK2 | Parkinsons disease (PD) | c.6055G>A,p.Gly2019Ser | rs34637584 |
|
|
| aspsirna0540 | UUCAAUAUAAAGGCUGGCG AAGUUAUAUUUCCGACCGC |
37 | 8 | 29 | LRRK2 | Parkinsons disease (PD) | c.4321C>G,p.Arg1441Gly | rs33939927 |
|
|
| aspsirna0541 | GCUGGCGCUUCUUCUUCCC CGACCGCGAAGAAGAAGGG |
71 | 10 | 61 | LRRK2 | Parkinsons disease (PD) | c.4321C>G,p.Arg1441Gly | rs33939927 |
|
|
| aspsirna0542 | UAAAGGCUGGCGCUUCUUC AUUUCCGACCGCGAAGAAG |
20 | 6 | 14 | LRRK2 | Parkinsons disease (PD) | c.4321C>G,p.Arg1441Gly | rs33939927 |
|
|
| aspsirna0543 | UAAAGGCUUGCGCUUCUUC AUUUCCGAACGCGAAGAAG |
63 | 75 | -12 | LRRK2 | Parkinsons disease (PD) | c.4321C>T,p.Arg1441Cys | rs33939927 |
|
|
| aspsirna0544 | GCUGACUACAGCAUUGCUC CGACUGAUGUCGUAACGAG |
40 | 86 | -46 | LRRK2 | Parkinsons disease (PD) | c.6055G>A,p.Gly2019Ser | rs34637584 |
|
|
| aspsirna0545 | CUACAGCAUUGCUCAGUAC GAUGUCGUAACGAGUCAUG |
29 | 4 | 25 | LRRK2 | Parkinsons disease (PD) | c.6055G>A,p.Gly2019Ser | rs34637584 |
|
|
| aspsirna0546 | UACAGCAUUGCUCAGUACU AUGUCGUAACGAGUCAUGA |
46 | 14 | 32 | LRRK2 | Parkinsons disease (PD) | c.6055G>A,p.Gly2019Ser | rs34637584 |
|
|
| aspsirna0547 | AGAUUGCUGACUACAGCAU UCUAACGACUGAUGUCGUA |
40 | 7 | 33 | LRRK2 | Parkinsons disease (PD) | c.6055G>A,p.Gly2019Ser | rs34637584 |
|
|
| aspsirna0548 | AAGAUUGCUGACUACAGCA UUCUAACGACUGAUGUCGU |
40 | 0 | 40 | LRRK2 | Parkinsons disease (PD) | c.6055G>A,p.Gly2019Ser | rs34637584 |
|