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Note: (i) 0 indicates modification in opposite strand. (ii) Multiple modifications are separated bt asterisk (*).

• By modification in sense strand


• By modification position in sense strand


• By modification in antisense strand


• By modification position in antisense strand


• Reference
Total number of Results for 2 are 23
Results from 0 - 25


SMDBid	siRNA (sense/antisense) 5'>3'	Modification (sense/antisense)	Position (sense/antisense)	Modified component (sense/antisense)	Efficacy (%)	Reference
SM2197	GCAGCACGACUUCUUCAAGUU CUUGAAGAAGUCGUGCUGCUU	2-O-Methyl 0	2 0	Sugar 0	71.74 percent target mRNA inhibition	18575806
SM2198	GCAGCACGACUUCUUCAAGUU CUUGAAGAAGUCGUGCUGCUU	2-O-Methyl 2-O-Methyl	2 2	Sugar Sugar	62.72 percent target mRNA inhibition	18575806
SM2199	GCAGCACGACUUCUUCAAGUU UUCGUCGUGCUGAAGAAGUUC	2-O-Methyl 2-Fluoro	2 2	Sugar Sugar	77.23 percent target mRNA inhibition	18575806
SM2202	UAGUUCUGUGGGGCUGUUUUU AAACAGCCCCACAGAACUAUU	2-O-Methyl 2-Fluoro	2 2	Sugar Sugar	NA	18575806
SM2448	AUCUGAAGAAGGAGAAAAAC UUUUUCUCCUUCUUCAGAUTT	N4-Ethyl-N4 2-Deoxy-5-Methylcytidine 0	2 0	Base 0	IC-50 = 0.013 nM for target mRNA	23362010
SM2652	CUUACGCUGAGUACUUCGATT UCGAAGUACUCAGCGUAAGTT	Morpholinouridine 0	2 0	Sugar 0	88 percent target mRNA inhibition	19233658
SM3282	GUAUUGACAGCUAUUCGAATT UUCGAAUAGCUGUCAAUACTT	Altritol nucleic acid 0	2 0	Sugar 0	42 percent target mRNA inhibition	17264131
SM3333	UGAGGUUUAGGAUUCGUGCUUGCACGAAUCCUAAACCUCA 0	2-O-Methyl 0	2 0	Sugar 0	70 percent target mRNA inhibition	19948766
SM3501	UUAAUGCUAAUCGUGAAGGGGUU CCCCUAUCACGAUUAGCAUUAAUA	2-O-Methyl 2-O-Methyl	2 14,20	Sugar Sugar	70 percent target mRNA inhibition	US20120088815A1, EP2415869A1
SM3542	CUAAGCCUGUUUCUUCCUCTT GAGGAAGAAACAGGCUUAGTT	2-Deoxy-2-Fluoro 0	2 0	Sugar 0	82 percent target mRNA inhibition	US20120088815A1, EP2415869A1
SM3678	UUAAGGAGAAGCUGACGGCTT GCCGUCAGCUUCUCCUUAATT	2-O-Methyl 2-O-Methyl	2 17	Sugar Sugar	69 percent target mRNA inhibition	US20120088815A1, EP2415869A1
SM3702	CUACCUUCUCCUCUUCUCCTT GGAGAAGAGGAGAAGGUAGTT	2-O-Methyl 2-O-Methyl	2 17	Sugar Sugar	69 percent target mRNA inhibition	US20120088815A1, EP2415869A1
SM3714	AUACUUGGCGGGCUCUUUCTT GAAAGAGCCCGCCAAGUAUTT	2-O-Methyl 0	2 0	Sugar 0	48 percent target mRNA inhibition	US20120088815A1, EP2415869A1
SM3730	GUACUCUGAUGAGGAAGAGTT CUCUUCCUCAUCAGAGUACTT	2-O-Methyl 0	2 0	Sugar 0	69 percent target mRNA inhibition	US20120088815A1, EP2415869A1
SM3846	UUAAAGGGCGAGAAGACCGTT CGGUCUUCUCGCCCUUUAATT	2-O-Methyl 2-O-Methyl	2 17	Sugar Sugar	87 percent target mRNA inhibition	US20120088815A1, EP2415869A1
SM3854	CUAGAGGAUCUUGAAGACCTT GGUCUUCAAGAUCCUCUAGTT	2-Deoxy-2-Fluoro 2-Deoxy-2-Fluoro	2 0	Sugar 0	81 percent target mRNA inhibition	US20120088815A1, EP2415869A1
SM3942	UUACAAAGGAUCUCCUCCCTT GGGAGGAGAUCCUUUGUAATT	2-O-Methyl 2-O-Methyl	2 17	Sugar Sugar	69 percent target mRNA inhibition	US20120088815A1, EP2415869A1
SM3950	UUACCCCGAUUCAGCCUCUTT AGAGGCUGAAUCGGGGUAATT	2-Deoxy-2-Fluoro 2-Deoxy-2-Fluoro	2 18	Sugar Sugar	69 percent target mRNA inhibition	US20120088815A1, EP2415869A1
SM3958	CUAGUCGAAAGAAAACGGGTT CCCGUUUUCUUUCGACUAGTT	2-O-Methyl 2-O-Methyl	2 17	Sugar Sugar	56 percent target mRNA inhibition	US20120088815A1, EP2415869A1
SM4098	UUAAGGAGAAGCUGACGGCTT GCCGUCAGCUUCUCCUUAATT	2-O-Methyl 2-O-Methyl	2 6,17	Sugar Sugar	83 percent target mRNA inhibition	US20120088815A1, EP2415869A1
SM4122	UUGGGGAAGCGGCCGGCGGTT CCGCCGGCCGCUUCCCCAATT	2-O-Methyl 2-O-Methyl	2 17	Sugar Sugar	82 percent target mRNA inhibition	US20120088815A1, EP2415869A1
SM4154	CUGACCGGAAGCGCUUAAATT UUUAAGCGCUUCCGGUCAGTT	2-Deoxy-2-Fluoro 2-Deoxy-2-Fluoro	2 3	Sugar Sugar	87 percent target mRNA inhibition	US20120088815A1, EP2415869A1
SM4162	ACAGAAAGAGUUCGAGGAGTT CUCCUCGAACUCUUUCUGUTT	2-O-Methyl 2-O-Methyl	2 17	Sugar Sugar	64 percent target mRNA inhibition	US20120088815A1, EP2415869A1