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Note: (i) 0 indicates modification in opposite strand. (ii) Multiple modifications are separated bt asterisk (*).
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  • By modification in antisense strand

  • By modification position in antisense strand

  • Reference
    • Total number of Results for 22 are 6
    Results from 0 - 25
    SMDBidsiRNA (sense/antisense) 5'>3'Modification (sense/antisense)Position (sense/antisense) Modified component (sense/antisense) Efficacy (%)Reference
    SM2375
    CUUCUUCGUCGAGACCAUGTTX
    CAUGGUCUCGACGAAGAAGTTX
    Thymidine analogue
    Thymidine analogue
    22
    22
    Base
    Base
    11 percent target mRNA inhibition
    23743279
    SM2376
    CUUCUUCGUCGAGACCAUGTTY
    CAUGGUCUCGACGAAGAAGTTY
    Glucosamine analogue
    Glucosamine analogue
    22
    22
    Base
    Base
    22 percent target mRNA inhibition
    23743279
    SM2382
    CUUCUUCGUCGAGACCAUGTTX
    CAUGGUCUCGACGAAGAAGTTX
    Thymidine analogue
    Thymidine analogue
    22
    22
    Base
    Base
    24 percent target mRNA inhibition
    23743279
    SM2383
    CUUCUUCGUCGAGACCAUGTTY
    CAUGGUCUCGACGAAGAAGTTY
    Glucosamine analogue
    Glucosamine analogue
    22
    22
    Base
    Base
    39 percent target mRNA inhibition
    23743279
    SM2389
    CUUCUUCGUCGAGACCAUGTTX
    CAUGGUCUCGACGAAGAAGTTX
    Thymidine analogue
    Thymidine analogue
    22
    22
    Base
    Base
    75 percent target mRNA inhibition
    23743279
    SM2390
    CUUCUUCGUCGAGACCAUGTTY
    CAUGGUCUCGACGAAGAAGTTY
    Glucosamine analogue
    Glucosamine analogue
    22
    22
    Base
    Base
    70 percent target mRNA inhibition
    23743279