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Note: (i) 0 indicates modification in opposite strand. (ii) Multiple modifications are separated bt asterisk (*).

• By modification in sense strand


• By modification position in sense strand


• By modification in antisense strand


• By modification position in antisense strand


• Reference
Total number of Results for 5 are 14
Results from 0 - 25


SMDBid	siRNA (sense/antisense) 5'>3'	Modification (sense/antisense)	Position (sense/antisense)	Modified component (sense/antisense)	Efficacy (%)	Reference
SM2608	GACGUAAACGGCCACAAGUUC ACUUGUGGCCGUUUACGUCGCU	2-O-Aminoethyl-ribose 2-O-Aminoethyl-ribose	5 20,21	Sugar Sugar	68 percent target mRNA inhibition	17904849
SM2609	GACGUAAACGGCCACAAGUUC ACUUGUGGCCGUUUACGUCGCU	2-O-Guanidinoethyl-ribose 2-O-Aminoethyl-ribose	5 20,21	Sugar Sugar	70 percent target mRNA inhibition	17904849
SM2611	GACGUAAACGGCCACAAGUUC ACUUGUGGCCGUUUACGUCGCU	2-O-Aminoethyl-ribose 2-O-Aminoethyl-ribose	5 1,20,21	Sugar Sugar	15 percent target mRNA inhibition	17904849
SM2612	GACGUAAACGGCCACAAGUUC ACUUGUGGCCGUUUACGUCGCU	2-O-Guanidinoethyl-ribose 2-O-Aminoethyl-ribose	5 1,20,21	Sugar Sugar	34 percent target mRNA inhibition	17904849
SM3281	GUAUUGACAGCUAUUCGAATT UUCGAAUAGCUGUCAAUACTT	Altritol nucleic acid 0	5 0	Sugar 0	42 percent target mRNA inhibition	17264131
SM3802	GCUGUAACCUCGGAGAGUUTT AACUCUCCGAGGUUACAGCTT	2-Deoxy-2-Fluoro 2-Deoxy-2-Fluoro	5 14	Sugar Sugar	69 percent target mRNA inhibition	US20120088815A1, EP2415869A1
SM3818	AAGUAGUCCCCCUUGAAGATT UCUUCAAGGGGGACUACUUTT	2-Deoxy-2-Fluoro 2-Deoxy-2-Fluoro	5 15	Sugar Sugar	69 percent target mRNA inhibition	US20120088815A1, EP2415869A1
SM3874	AGACUAAGCCCAAAAGGGCTT GCCCUUUUGGGCUUAGUCUTT	2-Deoxy-2-Fluoro 2-Deoxy-2-Fluoro	5 14	Sugar Sugar	47 percent target mRNA inhibition	US20120088815A1, EP2415869A1
SM3890	GGCUUAGUCACUCCUCUUCTT GAAGAGGAGUGACUAAGCCTT	2-Deoxy-2-Fluoro 2-Deoxy-2-Fluoro	5 14	Sugar Sugar	69 percent target mRNA inhibition	US20120088815A1, EP2415869A1
SM3894	ACCUUAAGGACCACCGGAUTT AUCCGGUGGUCCUUAAGGUTT	2-O-Methyl 2-O-Methyl	5 14	Sugar Sugar	74 percent target mRNA inhibition	US20120088815A1, EP2415869A1
SM3926	GGAAGUAAGGACCAGAGACTT GUCUCUGGUCCUUACUUCCTT	2-O-Methyl 2-O-Methyl	5 13	Sugar Sugar	44 percent target mRNA inhibition	US20120088815A1, EP2415869A1
SM4086	ACGUCACCGAGGAGAAGUATT UACUUCUCCUCGGUGACGUTT	2-O-Methyl 2-O-Methyl	5 1,14	Sugar Sugar	80 percent target mRNA inhibition	US20120088815A1, EP2415869A1
SM4126	AAGGCAUGCUUCGGAAACUTT AGUUUCCGAAGCAUGCCUUTT	2-O-Methyl 2-O-Methyl	5 12	Sugar Sugar	95 percent target mRNA inhibition	US20120088815A1, EP2415869A1
SM4170	ACCUUAAGGACCACCGGAUTT AUCCGGUGGUCCUUAAGGUTT	2-Deoxy-2-Fluoro 2-Deoxy-2-Fluoro	5 7	Sugar Sugar	71 percent target mRNA inhibition	US20120088815A1, EP2415869A1