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Note: (i) 0 indicates modification in opposite strand. (ii) Multiple modifications are separated bt asterisk (*).

• By modification in sense strand


• By modification position in sense strand


• By modification in antisense strand


• By modification position in antisense strand


• Reference
Total number of Results for 7 are 12
Results from 0 - 25


SMDBid	siRNA (sense/antisense) 5'>3'	Modification (sense/antisense)	Position (sense/antisense)	Modified component (sense/antisense)	Efficacy (%)	Reference
SM3444	AGCGCUUAAAGGGCGAGAAGAUU UCUUCUCGCCCUUUAAGCGCUUU	2-Deoxy-2-Fluoro 2-Deoxy-2-Fluoro	7 14,15	Sugar Sugar	44 percent target mRNA inhibition	US20120088815A1, EP2415869A1
SM3446	AGCGCUUAAAGGGCGAGAAGAUU UCUUCUCGCCCUUUAAGCGCUUU	2-O-Methyl 2-O-Methyl	7 15	Sugar Sugar	81 percent target mRNA inhibition	US20120088815A1, EP2415869A1
SM3447	AGCGCUUAAAGGGCGAGAAGAUU UCUUCUCGCCCUUUAAGCGCUUU	2-O-Methyl 2-O-Methyl	7 14	Sugar Sugar	49 percent target mRNA inhibition	US20120088815A1, EP2415869A1
SM3449	AGCGCUUAAAGGGCGAGAAGAUU UCUUCUCGCCCUUUAAGCGCUUU	2-Deoxy-2-Fluoro 0	7 0	Sugar 0	85 percent target mRNA inhibition	US20120088815A1, EP2415869A1
SM3459	AGCGCUUAAAGGGCGAGAAGAUU UCUUCUCGCCCUUUAAGCGCUUU	2-O-Methyl 0	7 0	Sugar 0	53 percent target mRNA inhibition	US20120088815A1, EP2415869A1
SM3460	AGCGCUUAAAGGGCGAGAAGAUU UCUUCUCGCCCUUUAAGCGCUUU	2-Deoxy-2-Fluoro 0	7 0	Sugar 0	78 percent target mRNA inhibition	US20120088815A1, EP2415869A1
SM3461	AGCGCUUAAAGGGCGGAAGAUU UCUUCUCGCCCUUUAAGCGCUUU	2-O-Methyl 2-O-Methyl	7 14	Sugar Sugar	50 percent target mRNA inhibition	US20120088815A1, EP2415869A1
SM3463	AGCGCUUAAAGGGCGAGAAGAUU UCUUCUCGCCCUUUAAGCGCUUU	Phosphodiester Phosphodiester	7 14	Sugar Sugar	45 percent target mRNA inhibition	US20120088815A1, EP2415869A1
SM3464	AGCGCUUAAAGGGCGAGAAGAUU UCUUCUCGCCCUUUAAGCGCUUU	2-Deoxy-2-Fluoro 2-Deoxy-2-Fluoro	7 15	Sugar Sugar	51 percent target mRNA inhibition	US20120088815A1, EP2415869A1
SM3638	UCCGGCUAACUCUGAGGACTT GUCCUCAGAGUUAGCCGGATT	2-Deoxy-2-Fluoro 2-Deoxy-2-Fluoro	7 12	Sugar Sugar	82 percent target mRNA inhibition	US20120088815A1, EP2415869A1
SM3826	AGCGCUUAAAGGGCGAGAAGATT UCUUCUCGCCCUUUAAGCGCUTT	2-O-Methyl 2-O-Methyl	7 14	Sugar Sugar	85 percent target mRNA inhibition	US20120088815A1, EP2415869A1
SM3898	CGGAUCUACACCUUCAAGATT UCUUGAAGGUGUAGAUCCGTT	2-O-Methyl 2-O-Methyl	7 12	Sugar Sugar	69 percent target mRNA inhibition	US20120088815A1, EP2415869A1