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Note: (i) 0 indicates modification in opposite strand. (ii) Multiple modifications are separated bt asterisk (*).

• By modification in sense strand


• By modification position in sense strand


• By modification in antisense strand


• By modification position in antisense strand


• Reference
Total number of Results for 7,8 are 5
Results from 0 - 25


SMDBid	siRNA (sense/antisense) 5'>3'	Modification (sense/antisense)	Position (sense/antisense)	Modified component (sense/antisense)	Efficacy (%)	Reference
SM3443	AGCGCUUAAAGGGCGAGAAGAUU UCUUCUCGCCCUUUAAGCGCUUU	2-O-Methyl 2-O-Methyl	7,8 14,15	Sugar Sugar	27 percent target mRNA inhibition	US20120088815A1, EP2415869A1
SM3445	AGCGCUUAAAGGGCGAGAAGAUU UCUUCUCGCCCUUUAAGCGCUUU	2-O-Methyl 2-O-Methyl	7,8 15	Sugar Sugar	56 percent target mRNA inhibition	US20120088815A1, EP2415869A1
SM3451	AGCGCUUAAAGGGCGAGAAGAUU UCUUCUCGCCCUUUAAGCGCUUU	2-O-Methyl 2-O-Methyl	7,8 14	Sugar Sugar	23 percent target mRNA inhibition	US20120088815A1, EP2415869A1
SM3455	AGCGCUUAAAGGGCGAGAAGAUU UCUUCUCGCCCUUUAAGCGCUUU	2-O-Methyl 0	7,8 0	Sugar 0	59 percent target mRNA inhibition	US20120088815A1, EP2415869A1
SM3594	AGUUUCUAGGGCCGUGGCCTT GGCCACGGCCCUAGAAACUTT	2-Deoxy-2-Fluoro 2-Deoxy-2-Fluoro	7,8 12	Sugar Sugar	82 percent target mRNA inhibition	US20120088815A1, EP2415869A1