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Note: (i) 0 indicates modification in opposite strand. (ii) Multiple modifications are separated bt asterisk (*).

• By modification in sense strand


• By modification position in sense strand


• By modification in antisense strand


• By modification position in antisense strand


• Reference
Total number of Results for 17163665 are 6
Results from 0 - 25


SMDBid	siRNA (sense/antisense) 5'>3'	Modification (sense/antisense)	Position (sense/antisense)	Modified component (sense/antisense)	Efficacy (%)	Reference
SM2586	CUUACGCUGAGUACUUCGATT UCGAAGUACUCAGCGUAAGTT	0 2,4-Difluorotoluene	0 1	0 Base	IC-50 = 0.27 nM for target mRNA	17163665
SM2587	CUUACGCUGAGUACUUCGATT UCGAAGUACUCAGCGUAAGTT	0 2,4-Difluorotoluene	0 7	0 Base	IC-50 = 0.27 nM for target mRNA	17163665
SM2588	CUUACGCUGAGUACUUCGATT UCGAAGUACUCAGCGUAAGTT	0 2,4-Difluorotoluene	0 16	0 Base	IC-50 = 0.58 nM for target mRNA	17163665
SM2589	CUUACGCUGAGUACUUCGATT UCGAAGUACUCAGCGUAAGTT	0 2,4-Difluorotoluene	0 9	0 Base	IC-50 (Less than than 30 nM) for target mRNA	17163665
SM2590	CUUACGCUGAGUACUUCGATT UCGAAGUACUCAGCGUAAGTT	0 2,4-Difluorotoluene	0 11	0 Base	IC-50 (Less than than 30 nM) for target mRNA	17163665
SM2591	CUUACGCUGAGUACUUCGATT UCGAAGUACUCAGCGUAAGTT	0 2,4-Difluorotoluene	0 10	0 Base	IC-50 = 1.2 nM for target mRNA	17163665