Browse By

Note: (i) 0 indicates modification in opposite strand. (ii) Multiple modifications are separated bt asterisk (*).
  • By modification in sense strand

  • By modification position in sense strand

  • By modification in antisense strand

  • By modification position in antisense strand

  • Reference
    • Total number of Results for 17904849 are 6
    Results from 0 - 25
    SMDBidsiRNA (sense/antisense) 5'>3'Modification (sense/antisense)Position (sense/antisense) Modified component (sense/antisense) Efficacy (%)Reference
    SM2607
    GACGUAAACGGCCACAAGUUC
    ACUUGUGGCCGUUUACGUCGCU
    2-O-Allyl-ribose
    2-O-Aminoethyl-ribose
    17
    20,21
    Sugar
    Sugar
    73 percent target mRNA inhibition
    17904849
    SM2608
    GACGUAAACGGCCACAAGUUC
    ACUUGUGGCCGUUUACGUCGCU
    2-O-Aminoethyl-ribose
    2-O-Aminoethyl-ribose
    5
    20,21
    Sugar
    Sugar
    68 percent target mRNA inhibition
    17904849
    SM2609
    GACGUAAACGGCCACAAGUUC
    ACUUGUGGCCGUUUACGUCGCU
    2-O-Guanidinoethyl-ribose
    2-O-Aminoethyl-ribose
    5
    20,21
    Sugar
    Sugar
    70 percent target mRNA inhibition
    17904849
    SM2610
    GACGUAAACGGCCACAAGUUC
    ACUUGUGGCCGUUUACGUCGCU
    2-O-Allyl-ribose
    2-O-Aminoethyl-ribose
    17
    1,20,21
    Sugar
    Sugar
    20 percent target mRNA inhibition
    17904849
    SM2611
    GACGUAAACGGCCACAAGUUC
    ACUUGUGGCCGUUUACGUCGCU
    2-O-Aminoethyl-ribose
    2-O-Aminoethyl-ribose
    5
    1,20,21
    Sugar
    Sugar
    15 percent target mRNA inhibition
    17904849
    SM2612
    GACGUAAACGGCCACAAGUUC
    ACUUGUGGCCGUUUACGUCGCU
    2-O-Guanidinoethyl-ribose
    2-O-Aminoethyl-ribose
    5
    1,20,21
    Sugar
    Sugar
    34 percent target mRNA inhibition
    17904849