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Note: (i) 0 indicates modification in opposite strand. (ii) Multiple modifications are separated bt asterisk (*).
- By modification in sense strand
- By modification position in sense strand
- By modification in antisense strand
- By modification position in antisense strand
- Reference
Total number of Results for 18094121 are 11
Results from 0 - 25
SMDBid | siRNA (sense/antisense) 5'>3' | Modification (sense/antisense) | Position (sense/antisense) |
Modified component (sense/antisense) |
Efficacy (%) | Reference |
SM2615 |
CGUACGCGGAAUACUUCGAUU TCGAAGUAUUCCGCGUACGUU |
0 Mutation* 5-O-Methyl |
0 1 * 1 |
0 Base; Sugar |
20 percent target mRNA inhibition | 18094121 |
SM2617 |
TGUACGCGGAAUACUUCGAUU UCGAAGUAUUCCGCGUACGUU |
Mutation* 5-O-Methyl 0 |
1 * 1 0 |
Base; Sugar 0 |
70 percent target mRNA inhibition | 18094121 |
SM2619 |
TUAGUCGAAUGCAAGACAAUT UUGUCUUGCAUUCGACUAAUT |
Mutation* 5-O-Methyl 0 |
1 * 1 0 |
Base; Sugar 0 |
54 percent target mRNA inhibition | 18094121 |
SM2620 |
UUAGUCGAAUGCAAGACAAUT TUGUCUUGCAUUCGACUAAUT |
0 Mutation* 5-O-Methyl |
0 1 * 1 |
0 Base; Sugar |
87 percent target mRNA inhibition | 18094121 |
SM2621 |
TUAGUCGAAUGCAAGACAAUT TUGUCUUGCAUUCGACUAAUT |
Mutation* 5-O-Methyl Mutation* 5-O-Methyl |
1 * 1 1 * 1 |
Base; Sugar Base; Sugar |
61 percent target mRNA inhibition | 18094121 |
SM2623 |
TUAAGAUCUGUUAUCCGCAUT UGCGGAUAACAGAUCUUAAUT |
Mutation* 5-O-Methyl 0 |
1 * 1 0 |
Base; Sugar 0 |
83 percent target mRNA inhibition | 18094121 |
SM2624 |
UUAAGAUCUGUUAUCCGCAUT TGCGGAUAACAGAUCUUAAUT |
0 Mutation* 5-O-Methyl |
0 1 * 1 |
0 Base; Sugar |
76 percent target mRNA inhibition | 18094121 |
SM2625 |
TUAAGAUCUGUUAUCCGCAUT TGCGGAUAACAGAUCUUAAUT |
Mutation* 5-O-Methyl Mutation* 5-O-Methyl |
1 * 1 1 * 1 |
Base; Sugar Base; Sugar |
68 percent target mRNA inhibition | 18094121 |
SM2632 |
TUAAGAUCUGUUAUCCGCAUT UGCGGAUAACAGAUCUUAAUT |
Mutation* 5-O-Methyl 0 |
1 * 1 0 |
Base; Sugar 0 |
4 percent target mRNA inhibition | 18094121 |
SM2633 |
UUAAGAUCUGUUAUCCGCAUT TGCGGAUAACAGAUCUUAAUT |
0 Mutation* 5-O-Methyl |
0 1 * 1 |
0 Base; Sugar |
60 percent target mRNA inhibition | 18094121 |
SM2634 |
TUAAGAUCUGUUAUCCGCAUT TGCGGAUAACAGAUCUUAAUT |
Mutation* 5-O-Methyl Mutation* 5-O-Methyl |
1 * 1 1 * 1 |
Base; Sugar Base; Sugar |
0 percent target mRNA inhibition | 18094121 |