A database of experimentally validated
chemically modified siRNAs
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Modification in sense
Position in sense strand
Modification in antisense
Position in antisense
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Note: (i) 0 indicates modification in opposite strand. (ii) Multiple modifications are separated bt asterisk (*).
By modification in sense strand
By modification position in sense strand
By modification in antisense strand
By modification position in antisense strand
Reference
Total number of Results for
22974833
are
1
Results from
0 - 25
SMDBid
siRNA (sense/antisense) 5'>3'
Modification (sense/antisense)
Position (sense/antisense)
Modified component (sense/antisense)
Efficacy (%)
Reference
SM2485
GTCATCACACUGAATACCAAUTT
AUUGGUAUUCAGUGUGAUGACTT
Locked nucleic acid
2,4-Locked nucleic acid
1,2,5,15,18,22,23
22,23
Sugar
Sugar
High target target mRNA inhibition efficacy
22974833