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Note: (i) 0 indicates modification in opposite strand. (ii) Multiple modifications are separated bt asterisk (*).
  • By modification in sense strand

  • By modification position in sense strand

  • By modification in antisense strand

  • By modification position in antisense strand

  • Reference
    • Total number of Results for 23362010 are 6
    Results from 0 - 25
    SMDBidsiRNA (sense/antisense) 5'>3'Modification (sense/antisense)Position (sense/antisense) Modified component (sense/antisense) Efficacy (%)Reference
    SM2448
    AUCUGAAGAAGGAGAAAAAC
    UUUUUCUCCUUCUUCAGAUTT
    N4-Ethyl-N4 2-Deoxy-5-Methylcytidine
    0
    2
    0
    Base
    0
    IC-50 = 0.013 nM for target mRNA
    23362010
    SM2449
    CAUCUGAAGAAGGAGAAAAAA
    UUUUUCUCCUUCUUCAGAUTT
    N6-Ethyl-N6 2-Deoxyadenosine
    0
    20
    0
    Base
    0
    IC-50 = 0.013 nM for target mRNA
    23362010
    SM2450
    AUCUGAAGAAGGAGAAAAATT
    UUUUUCUCCUUCUUCAGAUC
    0
    N4-Ethyl-N4 2-Deoxy-5-Methylcytidine
    0
    20
    0
    Base
    IC-50 = 0.03 nM for target mRNA
    23362010
    SM2451
    CAUCUGAAGAAGGAGAAAAATT
    UUUUUCUCCUUCUUCAGAUA
    0
    N6-Ethyl-N6 2-Deoxyadenosine
    0
    20
    0
    Base
    IC-50 = 0.028 nM for target mRNA
    23362010
    SM2452
    AUCUGAAGAAGGAGAAAAAC
    UUUUUCUCCUUCUUCAGAUC
    N4-Ethyl-N4 2-Deoxy-5-Methylcytidine
    N4-Ethyl-N4 2-Deoxy-5-Methylcytidine
    20
    20
    Base
    Base
    IC-50 = 0.033 nM for target mRNA
    23362010
    SM2453
    AUCUGAAGAAGGAGAAAAAA
    UUUUUCUCCUUCUUCAGAUA
    N6-ethyl-N6 2-Deoxyadenosine
    N6-Ethyl-N6 2-Deoxyadenosine
    20
    20
    Base
    Base
    IC-50 = 0.027 nM for target mRNA
    23362010