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Note: (i) 0 indicates modification in opposite strand. (ii) Multiple modifications are separated bt asterisk (*).
- By modification in sense strand
- By modification position in sense strand
- By modification in antisense strand
- By modification position in antisense strand
- Reference
Total number of Results for 2-Fluororibose* Xylo-O-methylribose* Phosphorothioate are 2
Results from 0 - 25
SMDBid | siRNA (sense/antisense) 5'>3' | Modification (sense/antisense) | Position (sense/antisense) |
Modified component (sense/antisense) |
Efficacy (%) | Reference |
SM4805 |
GGAUCAUCUCAAGUCUUACTT GUAAGACUUGAGAUGAUCCTT |
2-Fluororibose* Xylo-O-methylribose* Phosphorothioate 2-Fluororibose* Xylo-O-methylribose* Phosphorothioate |
4,5,7,8,9,10,15,16,17,19 * 14 * 20 4,5,7,8,9,10,15,16,17,19 * 14 * 20 |
Sugar Sugar |
IC-50 = 0.0076 nM for target mRNA | WO2014022739A3 |
SM4809 |
GGAUCAUCUCAAGUCUUACTT GUAAGACUUGAGAUGAUCCTT |
2-Fluororibose* Xylo-O-methylribose* Phosphorothioate 2-Fluororibose* Xylo-O-methylribose* Phosphorothioate |
4,7,8,9,10,15,16,17,19 * 5,14 * 20 4,7,8,9,10,15,16,17,19 * 5,14 * 20 |
Sugar Sugar |
IC-50 = 0.1822 nM for target mRNA | WO2014022739A3 |