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Note: (i) 0 indicates modification in opposite strand. (ii) Multiple modifications are separated bt asterisk (*).
- By modification in sense strand
- By modification position in sense strand
- By modification in antisense strand
- By modification position in antisense strand
- Reference
Total number of Results for 2-O-Methyl* 2-O-Benzyl are 8
Results from 0 - 25
SMDBid | siRNA (sense/antisense) 5'>3' | Modification (sense/antisense) | Position (sense/antisense) |
Modified component (sense/antisense) |
Efficacy (%) | Reference |
SM2456 |
CAAGUGUCAUCACACUGAAUU UUCAGUGUGAUGACACUUGUU |
2-O-Methyl* Inverted abasic 2-O-Methyl* 2-O-Benzyl |
20,21 * 1,21 20,21 * 5 |
Sugar; Base Sugar |
94 percent target mRNA inhibition | 23344622 |
SM2457 |
CAAGUGUCAUCACACUGAAUU UUCAGUGUGAUGACACUUGUU |
2-O-Methyl* Inverted abasic 2-O-Methyl* 2-O-Benzyl |
20,21 * 1,21 20,21 * 8 |
Sugar; Base Sugar |
96 percent target mRNA inhibition | 23344622 |
SM2458 |
CAAGUGUCAUCACACUGAAUU UUCAGUGUGAUGACACUUGUU |
2-O-Methyl* Inverted abasic 2-O-Methyl* 2-O-Benzyl |
20,21 * 1,21 20,21 * 15 |
Sugar; Base Sugar |
97 percent target mRNA inhibition | 23344622 |
SM2459 |
CAAGUGUCAUCACACUGAAUU UUCAGUGUGAUGACACUUGUU |
2-O-Methyl* Inverted abasic 2-O-Methyl* 2-O-Benzyl |
20,21 * 1,21 20,21 * 19 |
Sugar; Base Sugar |
92 percent target mRNA inhibition | 23344622 |
SM2461 |
CAAGUGUCAUCACACUGAAUU UUCAGUGUGAUGACACUUGUU |
2-O-Methyl* Inverted abasic 2-O-Methyl* 2-O-Benzyl |
20,21 * 1,21 20,21 * 5 |
Sugar; Base Sugar |
78 percent target mRNA inhibition | 23344622 |
SM2462 |
CAAGUGUCAUCACACUGAAUU UUCAGUGUGAUGACACUUGUU |
2-O-Methyl* Inverted abasic 2-O-Methyl* 2-O-Benzyl |
20,21 * 1,21 20,21 * 8 |
Sugar; Base Sugar |
87 percent target mRNA inhibition | 23344622 |
SM2463 |
CAAGUGUCAUCACA CUGAAUU UUCAGUGUGAUGACACUUGUU |
2-O-Methyl* Inverted abasic 2-O-Methyl* 2-O-Benzyl |
20,21 * 1,21 20,21 * 15 |
Sugar; Base Sugar |
87 percent target mRNA inhibition | 23344622 |
SM2464 |
CAAGUGUCAUCACA CUGAAUU UUCAGUGUGAUGACACUUGUU |
2-O-Methyl* Inverted abasic 2-O-Methyl* 2-O-Benzyl |
20,21 * 1,21 20,21 * 19 |
Sugar; Base Sugar |
72 percent target mRNA inhibition | 23344622 |