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Note: (i) 0 indicates modification in opposite strand. (ii) Multiple modifications are separated bt asterisk (*).
  • By modification in sense strand

  • By modification position in sense strand

  • By modification in antisense strand

  • By modification position in antisense strand

  • Reference
    • Total number of Results for Deoxyadenine are 9
    Results from 0 - 25
    SMDBidsiRNA (sense/antisense) 5'>3'Modification (sense/antisense)Position (sense/antisense) Modified component (sense/antisense) Efficacy (%)Reference
    SM2423
    GGAUAUUGUCAGUCUUUAGGUUUUU
    CCUAAAGACUGACAAUAUCCAAAAA
    Deoxyuridine
    Deoxyadenine
    21,22,23,24,25
    21,22,23,24,25
    Sugar
    Sugar
    62 percent target mRNA inhibition
    23449220
    SM2424
    GGAUAUUGUCAGUCUUUAGGUUUUU
    CCUAAAGACUGACAAUAUCCAAAAA
    5-Fluoro-2-Deoxyuridine* Deoxyuridine
    Deoxyadenine
    4 * 21,22,23,24,25
    21,22,23,24,25
    Sugar
    Sugar
    62 percent target mRNA inhibition
    23449220
    SM2425
    GGAUAUUGUCAGUCUUUAGGUUUUU
    CCUAAAGACUGACAAUAUCCAAAAA
    5-Fluoro-2-Deoxyuridine* Deoxyuridine
    Deoxyadenine
    21 * 22,23,24,25
    21,22,23,24,25
    Sugar
    Sugar
    NA
    23449220
    SM2426
    GGAUAUUGUCAGUCUUUAGGUUUUU
    CCUAAAGACUGACAAUAUCCAAAAA
    5-Fluoro-2-Deoxyuridine
    Deoxyadenine
    21,22,23,24,25
    21,22,23,24,25
    Sugar
    Sugar
    62 percent target mRNA inhibition
    23449220
    SM2431
    GGAUAUUGUCAGUCUUUAGGAAAAA
    CCUAAAGACUGACAAUAUCCAAAAA
    Deoxyadenine
    Deoxyadenine
    21,22,23,24,25
    21,22,23,24,25
    Sugar
    Sugar
    NA
    23449220
    SM2436
    GGAUAUUGUCAGUCUUUAGGUUUUU
    CCUAAAGACUGACAAUAUCCAAAAA
    Deoxyuridine
    Deoxyadenine
    21,22,23,24,25
    21,22,23,24,25
    Sugar
    Sugar
    13 percent target mRNA inhibition
    23449220
    SM2437
    GGAUAUUGUCAGUCUUUAGGUUUUU
    CCUAAAGACUGACAAUAUCCAAAAA
    5-Fluoro-2-Deoxyuridine
    Deoxyadenine
    21,22,23,24,25
    21,22,23,24,25
    Sugar
    Sugar
    15 percent target mRNA inhibition
    23449220
    SM2442
    GGAUAUUGUCAGUCUUUAGGUUUUU
    CCUAAAGACUGACAAUAUCCAAAAA
    Deoxyuridine
    Deoxyadenine
    21,22,23,24,25
    21,22,23,24,25
    Sugar
    Sugar
    80 percent target mRNA inhibition
    23449220
    SM2443
    GGAUAUUGUCAGUCUUUAGGUUUUU
    CCUAAAGACUGACAAUAUCCAAAAA
    5-Fluoro-2-Deoxyuridine
    Deoxyadenine
    21,22,23,24,25
    21,22,23,24,25
    Sugar
    Sugar
    83 percent target mRNA inhibition
    23449220