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Note: (i) 0 indicates modification in opposite strand. (ii) Multiple modifications are separated bt asterisk (*).

• By modification in sense strand


• By modification position in sense strand


• By modification in antisense strand


• By modification position in antisense strand


• Reference
Total number of Results for Locked nucleic acid* Thymidine are 2
Results from 0 - 25


SMDBid	siRNA (sense/antisense) 5'>3'	Modification (sense/antisense)	Position (sense/antisense)	Modified component (sense/antisense)	Efficacy (%)	Reference
SM4660	CUUACGCUGAGUACUUCGATT UCGAAGUACUCAGCGUAAGTT	0 Locked nucleic acid* Thymidine	0 10 * 10	0 Sugar ; Base	95 percent target mRNA inhibition	US 20080249039 A1
SM4669	CUUACGCUGAGUACUUCGATT UCGAAGUACUCAGCGUAAGTT	0 Locked nucleic acid* Thymidine	0 10 * 10	0 Sugar ; Base	91 percent target mRNA inhibition	US 20080249039 A1