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Note: (i) 0 indicates modification in opposite strand. (ii) Multiple modifications are separated bt asterisk (*).
  • By modification in sense strand

  • By modification position in sense strand

  • By modification in antisense strand

  • By modification position in antisense strand

  • Reference
    • Total number of Results for Tricyclodeoxyribonucleic acid are 24
    Results from 0 - 25
    SMDBidsiRNA (sense/antisense) 5'>3'Modification (sense/antisense)Position (sense/antisense) Modified component (sense/antisense) Efficacy (%)Reference
    SM3240
    GCAGCACGACUUCUUCAAGTT
    CUUGAAGAAGUCGUGCUGCTT
    0
    Tricyclodeoxyribonucleic acid
    0
    20,21
    0
    Sugar
    79 percent target mRNA inhibition
    21687522
    SM3241
    GCAGCACGACUUCUUCAAGTT
    CUUGAAGAAGTCGUGCUGCTT
    0
    Tricyclodeoxyribonucleic acid
    0
    11,20,21
    0
    Sugar
    88 percent target mRNA inhibition
    21687522
    SM3242
    GCAGCACGACUUCUUCAAGTT
    CUUGAAGAAGUCGUGCTGCTT
    0
    Tricyclodeoxyribonucleic acid
    0
    16,17,19,20,21
    0
    Sugar
    25 percent target mRNA inhibition
    21687522
    SM3243
    GCAGCACGACUUCUUCAAGTT
    CTTGAAGAAGUCGUGCUGCTT
    0
    Tricyclodeoxyribonucleic acid
    0
    1,2,3,20,21
    0
    Sugar
    12 percent target mRNA inhibition
    21687522
    SM3244
    GCAGCACGACUUCUUCAAGTT
    CUUGAAGAAGUCGUGCUGCTT
    Tricyclodeoxyribonucleic acid
    Tricyclodeoxyribonucleic acid
    20,21
    20,21
    Sugar
    Sugar
    81 percent target mRNA inhibition
    21687522
    SM3245
    GCAGCACGACUUCUUCAAGTT
    CUUGAAGAAGTCGUGCUGCTT
    Tricyclodeoxyribonucleic acid
    Tricyclodeoxyribonucleic acid
    10,20,21
    11,20,21
    Sugar
    Sugar
    88 percent target mRNA inhibition
    21687522
    SM3246
    GCAGCACGACUUCTTCAAGTT
    CUUGAAGAAGTCGUGCUGCTT
    Tricyclodeoxyribonucleic acid
    Tricyclodeoxyribonucleic acid
    13,14,15,16,20,21
    11,20,21
    Sugar
    Sugar
    89 percent target mRNA inhibition
    21687522
    SM3247
    GCAGCACGACUUCTTCAAGTT
    CUUGAAGAAGUCGUGCTGCTT
    Tricyclodeoxyribonucleic acid
    Tricyclodeoxyribonucleic acid
    13,14,15,16,20,21
    16,17,19,20,21
    Sugar
    Sugar
    23 percent target mRNA inhibition
    21687522
    SM3254
    GCAGCACGACUUCUUCAAGTT
    CUUGAAGAAGUCGUGCUGCTT
    0
    Tricyclodeoxyribonucleic acid
    0
    20,21
    0
    Sugar
    70 percent target mRNA inhibition
    21687522
    SM3255
    GCAGCACGACUUCUUCAAGTT
    CUUGAAGAAGTCGUGCUGCTT
    0
    Tricyclodeoxyribonucleic acid
    0
    11,20,21
    0
    Sugar
    85 percent target mRNA inhibition
    21687522
    SM3256
    GCAGCACGACUUCUUCAAGTT
    CUUGAAGAAGUCGUGCTGCTT
    0
    Tricyclodeoxyribonucleic acid
    0
    16,17,19,20,21
    0
    Sugar
    NA
    21687522
    SM3257
    GCAGCACGACUUCUUCAAGTT
    CTTGAAGAAGUCGUGCUGCTT
    0
    Tricyclodeoxyribonucleic acid
    0
    1,2,3,20,21
    0
    Sugar
    NA
    21687522
    SM3258
    GCAGCACGACUUCUUCAAGTT
    CUUGAAGAAGUCGUGCUGCTT
    Tricyclodeoxyribonucleic acid
    Tricyclodeoxyribonucleic acid
    20,21
    20,21
    Sugar
    Sugar
    71 percent target mRNA inhibition
    21687522
    SM3259
    GCAGCACGACUUCUUCAAGTT
    CUUGAAGAAGTCGUGCUGCTT
    Tricyclodeoxyribonucleic acid
    Tricyclodeoxyribonucleic acid
    10,20,21
    11,20,21
    Sugar
    Sugar
    85 percent target mRNA inhibition
    21687522
    SM3260
    GCAGCACGACUUCTTCAAGTT
    CUUGAAGAAGTCGUGCUGCTT
    Tricyclodeoxyribonucleic acid
    Tricyclodeoxyribonucleic acid
    13,14,15,16,20,21
    11,20,21
    Sugar
    Sugar
    86 percent target mRNA inhibition
    21687522
    SM3261
    GCAGCACGACUUCTTCAAGTT
    CUUGAAGAAGUCGUGCTGCTT
    Tricyclodeoxyribonucleic acid
    Tricyclodeoxyribonucleic acid
    13,14,15,16,20,21
    16,17,19,20,21
    Sugar
    Sugar
    6 percent target mRNA inhibition
    21687522
    SM3268
    GCAGCACGACUUCUUCAAGTT
    CUUGAAGAAGUCGUGCUGCTT
    0
    Tricyclodeoxyribonucleic acid
    0
    20,21
    0
    Sugar
    46 percent target mRNA inhibition
    21687522
    SM3269
    GCAGCACGACUUCUUCAAGTT
    CUUGAAGAAGTCGUGCUGCTT
    0
    Tricyclodeoxyribonucleic acid
    0
    11,20,21
    0
    Sugar
    74 percent target mRNA inhibition
    21687522
    SM3270
    GCAGCACGACUUCUUCAAGTT
    CUUGAAGAAGUCGUGCTGCTT
    0
    Tricyclodeoxyribonucleic acid
    0
    16,17,19,20,21
    0
    Sugar
    NA
    21687522
    SM3271
    GCAGCACGACUUCUUCAAGTT
    CTTGAAGAAGUCGUGCUGCTT
    0
    Tricyclodeoxyribonucleic acid
    0
    1,2,3,20,21
    0
    Sugar
    NA
    21687522
    SM3272
    GCAGCACGACUUCUUCAAGTT
    CUUGAAGAAGUCGUGCUGCTT
    Tricyclodeoxyribonucleic acid
    Tricyclodeoxyribonucleic acid
    20,21
    20,21
    Sugar
    Sugar
    51 percent target mRNA inhibition
    21687522
    SM3273
    GCAGCACGACUUCUUCAAGTT
    CUUGAAGAAGTCGUGCUGCTT
    Tricyclodeoxyribonucleic acid
    Tricyclodeoxyribonucleic acid
    10,20,21
    11,20,21
    Sugar
    Sugar
    80 percent target mRNA inhibition
    21687522
    SM3274
    GCAGCACGACUUCTTCAAGTT
    CUUGAAGAAGTCGUGCUGCTT
    Tricyclodeoxyribonucleic acid
    Tricyclodeoxyribonucleic acid
    13,14,15,16,20,21
    11,20,21
    Sugar
    Sugar
    84 percent target mRNA inhibition
    21687522
    SM3275
    GCAGCACGACUUCTTCAAGTT
    CUUGAAGAAGUCGUGCTGCTT
    Tricyclodeoxyribonucleic acid
    Tricyclodeoxyribonucleic acid
    13,14,15,16,20,21
    16,17,19,20,21
    Sugar
    Sugar
    4 percent target mRNA inhibition
    21687522