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Note: (i) 0 indicates modification in opposite strand. (ii) Multiple modifications are separated bt asterisk (*).
- By modification in sense strand
- By modification position in sense strand
- By modification in antisense strand
- By modification position in antisense strand
- Reference
Total number of Results for 1,2,3,11,12,14,16,17,19 are 2
Results from 0 - 25
SMDBid | siRNA (sense/antisense) 5'>3' | Modification (sense/antisense) | Position (sense/antisense) |
Modified component (sense/antisense) |
Efficacy (%) | Reference |
SM2977 |
GCAGCACGACUUCUUCAAGTT CUUGAAGAAGUCGUGCUGCTT |
0 2-Fluoro |
0 1,2,3,11,12,14,16,17,19 |
0 Sugar |
83 percent target mRNA inhibition | 12923253 |
SM2979 |
GCAGCACGACUUCUUCAAGTT CUUGAAGAAGUCGUGCUGCTT |
2-Fluoro 2-Fluoro |
2,5,7,10,11,12,13,14,15,16 1,2,3,11,12,14,16,17,19 |
Sugar Sugar |
83 percent target mRNA inhibition | 12923253 |