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Note: (i) 0 indicates modification in opposite strand. (ii) Multiple modifications are separated bt asterisk (*).
- By modification in sense strand
- By modification position in sense strand
- By modification in antisense strand
- By modification position in antisense strand
- Reference
Total number of Results for 1 * 1 are 8
Results from 0 - 25
| SMDBid | siRNA (sense/antisense) 5'>3' | Modification (sense/antisense) | Position (sense/antisense) |
Modified component (sense/antisense) |
Efficacy (%) | Reference |
|---|
| SM2615 |
CGUACGCGGAAUACUUCGAUU
TCGAAGUAUUCCGCGUACGUU |
0
Mutation* 5-O-Methyl |
0
1 * 1 |
0
Base; Sugar |
20 percent target mRNA inhibition | 18094121 |
| SM2620 |
UUAGUCGAAUGCAAGACAAUT
TUGUCUUGCAUUCGACUAAUT |
0
Mutation* 5-O-Methyl |
0
1 * 1 |
0
Base; Sugar |
87 percent target mRNA inhibition | 18094121 |
| SM2621 |
TUAGUCGAAUGCAAGACAAUT
TUGUCUUGCAUUCGACUAAUT |
Mutation* 5-O-Methyl
Mutation* 5-O-Methyl |
1 * 1
1 * 1 |
Base; Sugar
Base; Sugar |
61 percent target mRNA inhibition | 18094121 |
| SM2624 |
UUAAGAUCUGUUAUCCGCAUT
TGCGGAUAACAGAUCUUAAUT |
0
Mutation* 5-O-Methyl |
0
1 * 1 |
0
Base; Sugar |
76 percent target mRNA inhibition | 18094121 |
| SM2625 |
TUAAGAUCUGUUAUCCGCAUT
TGCGGAUAACAGAUCUUAAUT |
Mutation* 5-O-Methyl
Mutation* 5-O-Methyl |
1 * 1
1 * 1 |
Base; Sugar
Base; Sugar |
68 percent target mRNA inhibition | 18094121 |
| SM2633 |
UUAAGAUCUGUUAUCCGCAUT
TGCGGAUAACAGAUCUUAAUT |
0
Mutation* 5-O-Methyl |
0
1 * 1 |
0
Base; Sugar |
60 percent target mRNA inhibition | 18094121 |
| SM2634 |
TUAAGAUCUGUUAUCCGCAUT
TGCGGAUAACAGAUCUUAAUT |
Mutation* 5-O-Methyl
Mutation* 5-O-Methyl |
1 * 1
1 * 1 |
Base; Sugar
Base; Sugar |
0 percent target mRNA inhibition | 18094121 |
| SM2869 |
CAAGUGUCAUCACACUGAATT
UUCAGUGUGAUGACACUUGTT |
0
Hypoxanthine* 2-O-Benzyl |
0
1 * 1 |
0
Base; Sugar |
33 percent target mRNA inhibition | 21942264 |