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Note: (i) 0 indicates modification in opposite strand. (ii) Multiple modifications are separated bt asterisk (*).
  • By modification in sense strand

  • By modification position in sense strand

  • By modification in antisense strand

  • By modification position in antisense strand

  • Reference
    • Total number of Results for 2-Deoxythymidine* Cholesterol are 7
    Results from 0 - 25
    SMDBidsiRNA (sense/antisense) 5'>3'Modification (sense/antisense)Position (sense/antisense) Modified component (sense/antisense) Efficacy (%)Reference
    SM4385
    CUUACGCUGAGUACUUCGATT
    UCGAAGUACUCAGCGUAAGTT
    2-Deoxythymidine* Cholesterol
    2-Deoxythymidine
    1 * 20,21
    20,21
    Sugar ; Base
    Sugar
    65 percent target mRNA inhibition
    25699137
    SM4400
    CUUACGCUGAGUACUUCGATT
    UCGAAGUACUCAGCGUAAGTT
    2-Deoxythymidine* Cholesterol
    2-Deoxythymidine
    1 * 20,21
    20,21
    Sugar ; Base
    Sugar
    90 percent target mRNA inhibition
    25699137
    SM4407
    GUGAAGUCAACAUGCCUGCTT
    GCAGGCAUGUUGACUUCACTT
    2-Deoxythymidine* Cholesterol
    2-Deoxythymidine
    20,21 * 21
    20,21
    Sugar ; Base
    Sugar
    64 percent target mRNA inhibition
    25699137
    SM4414
    GUGAAGUCAACAUGCCUGCTT
    GCAGGCAUGUUGACUUCACTT
    2-Deoxythymidine* Cholesterol
    2-Deoxythymidine
    20,21 * 21
    20,21
    Sugar ; Base
    Sugar
    75 percent target mRNA inhibition
    25699137
    SM4418
    CUUACGCUGAGUACUUCGATT
    UCGAAGUACUCAGCGUAAGTT
    2-Deoxythymidine* Cholesterol
    2-Deoxythymidine
    1 * 20,21
    20,21
    Sugar ; Base
    Sugar
    40 percent target mRNA inhibition
    25699137
    SM4422
    CUUACGCUGAGUACUUCGATT
    UCGAAGUACUCAGCGUAAGTT
    2-Deoxythymidine* Cholesterol
    2-Deoxythymidine
    1 * 20,21
    20,21
    Sugar ; Base
    Sugar
    60 percent target mRNA inhibition
    25699137
    SM4426
    CUUACGCUGAGUACUUCGATT
    UCGAAGUACUCAGCGUAAGTT
    2-Deoxythymidine* Cholesterol
    2-Deoxythymidine
    1 * 20,21
    20,21
    Sugar ; Base
    Sugar
    79 percent target mRNA inhibition
    25699137