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Note: (i) 0 indicates modification in opposite strand. (ii) Multiple modifications are separated bt asterisk (*).
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  • By modification in antisense strand

  • By modification position in antisense strand

  • Reference
    • Total number of Results for 2-Deoxythymidine (Mutation) are 5
    Results from 0 - 25
    SMDBidsiRNA (sense/antisense) 5'>3'Modification (sense/antisense)Position (sense/antisense) Modified component (sense/antisense) Efficacy (%)Reference
    SM2494
    CGUGAGCACAAAGAAAAUGAGTT
    CUCAUUUUCUUUGUGCUCACGTT
    2-Deoxythymidine (Mutation)
    2-Deoxythymidine (Mutation)
    22,23 (4,9,13,18)
    22,23 (4,9,13,18)
    Sugar (Base)
    Sugar (Base)
    Low mRNA target inhibition efficacy
    12771196
    SM2500
    TTCGUGAGCACAAAGAAAAUGAG
    TTCUCAUUUUCUUUGUGCUCACG
    2-Deoxythymidine (Mutation)
    2-Deoxythymidine
    1,2 (6,11,15,20)
    1,2
    Sugar (Base)
    Sugar
    Low mRNA target inhibition efficacy
    12771196
    SM2502
    UGGUAUCAAGCUCAGGAAUAUTT
    AUAUUCCUGAGCUUGAUACCATT
    2-Deoxythymidine (Mutation)
    2-Deoxythymidine
    22,23 (4,7,10,12,14,20)
    22,23
    Sugar (Base)
    Sugar
    Low mRNA target inhibition efficacy
    12771196
    SM2510
    GGAGGGGAGUACAUCAAGUTT
    ACUUGAUGUACUCCCCUCCTT
    2-Deoxythymidine (Mutation)
    2-Deoxythymidine (Mutation)
    20,21 (1,19)
    20,21 (1,19)
    Sugar (Base)
    Sugar (Base)
    High target mRNA inhibition efficacy
    12771196
    SM2511
    GCAGGGGAGUACAUCAACUTT
    AGUUGAUGUACUCCCCUGCTT
    2-Deoxythymidine (Mutation)
    2-Deoxythymidine (Mutation)
    20,21 (1,2,18,19)
    20,21 (1,2,18,19)
    Sugar (Base)
    Sugar (Base)
    High target mRNA inhibition efficacy
    12771196