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Note: (i) 0 indicates modification in opposite strand. (ii) Multiple modifications are separated bt asterisk (*).

• By modification in sense strand


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• By modification in antisense strand


• By modification position in antisense strand


• Reference
Total number of Results for Altritol nucleic acid* 2-Deoxy are 144
Results from 0 - 25

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SMDBid	siRNA (sense/antisense) 5'>3'	Modification (sense/antisense)	Position (sense/antisense)	Modified component (sense/antisense)	Efficacy (%)	Reference
SM0005	GACGUAAACGGCCACAAGUUCT ACUUGUGGCCGUUUACGUCGC	Altritol nucleic acid* 2-Deoxy 2-O-Methyl	1,2 * 22 2	Sugar Sugar	81.4 percent target mRNA inhibition	19282453
SM0006	GACGUAAACGGCCACAAGUUCT ACUUGUGGCCGUUUACGUCGC	Altritol nucleic acid* 2-Deoxy 2-O-Methyl	18,19 * 22 2	Sugar Sugar	71.3 percent target mRNA inhibition	19282453
SM0007	GACGUAAACGGCCACAAGUUCT ACUUGUGGCCGUUUACGUCGC	Altritol nucleic acid* 2-Deoxy 2-O-Methyl	5,8,11,14,17 * 22 2	Sugar Sugar	25.7 percent target mRNA inhibition	19282453
SM0051	GACGUAAACGGCCACAAGUUCT ACUUGUGGCCGUUUACGUCGCU	Altritol nucleic acid* 2-Deoxy 2-O-Methyl* 2-Aminoethyl	1,2 * 22 1 * 21	Sugar Sugar	82 percent target mRNA inhibition	19282453
SM0052	GACGUAAACGGCCACAAGUUCT ACUUGUGGCCGUUUACGUCGCU	Altritol nucleic acid* 2-Deoxy 2-O-Methyl* 2-Aminoethyl	18,19 * 22 1 * 21	Sugar Sugar	74 percent target mRNA inhibition	19282453
SM0053	GACGUAAACGGCCACAAGUUCT ACUUGUGGCCGUUUACGUCGCU	Altritol nucleic acid* 2-Deoxy 2-O-Methyl* 2-Aminoethyl	5,8,11,14,17 * 22 1 * 21	Sugar Sugar	15 percent target mRNA inhibition	19282453
SM0096	GACGUAAACGGCCACAAGUUCT ACUUGUGGCCGUUUACGUCGCU	Altritol nucleic acid* 2-Deoxy 2-O-Methyl* 2-Cyanoethyl	1,2 * 22 1 * 18	Sugar Sugar	54.8 percent target mRNA inhibition	19282453
SM0097	GACGUAAACGGCCACAAGUUCT ACUUGUGGCCGUUUACGUCGCU	Altritol nucleic acid* 2-Deoxy 2-O-Methyl* 2-Cyanoethyl	18,19 * 22 1 * 18	Sugar Sugar	33.7 percent target mRNA inhibition	19282453
SM0098	GACGUAAACGGCCACAAGUUCT ACUUGUGGCCGUUUACGUCGCU	Altritol nucleic acid* 2-Deoxy 2-O-Methyl* 2-Cyanoethyl	5,8,11,14,17 * 22 1 * 18	Sugar Sugar	6.7 percent target mRNA inhibition	19282453
SM0141	GACGUAAACGGCCACAAGUUCT ACUUGUGGCCGUUUACGUCGC	Altritol nucleic acid* 2-Deoxy Altritol nucleic acid	1,2 * 22 1,2	Sugar Sugar	57.1 percent target mRNA inhibition	19282453
SM0142	GACGUAAACGGCCACAAGUUCT ACUUGUGGCCGUUUACGUCGC	Altritol nucleic acid* 2-Deoxy Altritol nucleic acid	18,19 * 22 1,2	Sugar Sugar	51.6 percent target mRNA inhibition	19282453
SM0143	GACGUAAACGGCCACAAGUUCT ACUUGUGGCCGUUUACGUCGC	Altritol nucleic acid* 2-Deoxy Altritol nucleic acid	5,8,11,14,17 * 22 1,2	Sugar Sugar	36.3 percent target mRNA inhibition	19282453
SM0186	GACGUAAACGGCCACAAGUUCT ACUUGUGGCCGUUUACGUCGCU	Altritol nucleic acid* 2-Deoxy Altritol nucleic acid	1,2 * 22 20,21	Sugar Sugar	88.5 percent target mRNA inhibition	19282453
SM0187	GACGUAAACGGCCACAAGUUCT ACUUGUGGCCGUUUACGUCGCU	Altritol nucleic acid* 2-Deoxy Altritol nucleic acid	18,19 * 22 20,21	Sugar Sugar	90.5 percent target mRNA inhibition	19282453
SM0188	GACGUAAACGGCCACAAGUUCT ACUUGUGGCCGUUUACGUCGCU	Altritol nucleic acid* 2-Deoxy Altritol nucleic acid	5,8,11,14,17 * 22 20,21	Sugar Sugar	68.4 percent target mRNA inhibition	19282453
SM0231	GACGUAAACGGCCACAAGUUCT ACUUGUGGCCGUUUACGUCGCU	Altritol nucleic acid* 2-Deoxy Altritol nucleic acid	1,2 * 22 5,8,11,14,17,20	Sugar Sugar	0 percent target mRNA inhibition	19282453
SM0232	GACGUAAACGGCCACAAGUUCT ACUUGUGGCCGUUUACGUCGCU	Altritol nucleic acid* 2-Deoxy Altritol nucleic acid	18,19 * 22 5,8,11,14,17,20	Sugar Sugar	7.8 percent target mRNA inhibition	19282453
SM0233	GACGUAAACGGCCACAAGUUCT ACUUGUGGCCGUUUACGUCGCU	Altritol nucleic acid* 2-Deoxy Altritol nucleic acid	5,8,11,14,17 * 22 5,8,11,14,17,20	Sugar Sugar	0 percent target mRNA inhibition	19282453
SM0276	GACGUAAACGGCCACAAGUUCT ACUUGUGGCCGUUUACGUCGCU	Altritol nucleic acid* 2-Deoxy Altritol nucleic acid	1,2 * 22 3,6,14,18,20,21	Sugar Sugar	80.3 percent target mRNA inhibition	19282453
SM0277	GACGUAAACGGCCACAAGUUCT ACUUGUGGCCGUUUACGUCGCU	Altritol nucleic acid* 2-Deoxy Altritol nucleic acid	18,19 * 22 3,6,14,18,20,21	Sugar Sugar	76 percent target mRNA inhibition	19282453
SM0278	GACGUAAACGGCCACAAGUUCT ACUUGUGGCCGUUUACGUCGCU	Altritol nucleic acid* 2-Deoxy Altritol nucleic acid	5,8,11,14,17 * 22 3,6,14,18,20,21	Sugar Sugar	4.3 percent target mRNA inhibition	19282453
SM0321	GACGUAAACGGCCACAAGUUCT ACUUGUGGCCGUUUACGUCGT	Altritol nucleic acid* 2-Deoxy Hexitol nucleic acid* 2-Deoxy	1,2 * 22 18,19,20 * 21	Sugar Sugar	85.4 percent target mRNA inhibition	19282453
SM0322	GACGUAAACGGCCACAAGUUCT ACUUGUGGCCGUUUACGUCGT	Altritol nucleic acid* 2-Deoxy Hexitol nucleic acid* 2-Deoxy	18,19 * 22 18,19,20 * 21	Sugar Sugar	84.2 percent target mRNA inhibition	19282453
SM0323	GACGUAAACGGCCACAAGUUCT ACUUGUGGCCGUUUACGUCGT	Altritol nucleic acid* 2-Deoxy Hexitol nucleic acid* 2-Deoxy	5,8,11,14,17 * 22 18,19,20 * 21	Sugar Sugar	19.8 percent target mRNA inhibition	19282453
SM0366	GACGUAAACGGCCACAAGUUCT ACUUGUGGCCGUUUACGUCGT	Altritol nucleic acid* 2-Deoxy Hexitol nucleic acid* 2-Deoxy	1,2 * 22 2,18,19,20 * 21	Sugar Sugar	75.4 percent target mRNA inhibition	19282453



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