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Note: (i) 0 indicates modification in opposite strand. (ii) Multiple modifications are separated bt asterisk (*).
  • By modification in sense strand

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  • By modification in antisense strand

  • By modification position in antisense strand

  • Reference
    • Total number of Results for Cholesterol* Fluorouridine* Phosphorothioate are 4
    Results from 0 - 25
    SMDBidsiRNA (sense/antisense) 5'>3'Modification (sense/antisense)Position (sense/antisense) Modified component (sense/antisense) Efficacy (%)Reference
    SM2471
    GAGGCUGGGAUGCCUUUTT
    AAAGGCAUCCCAGCCUCCGTT
    Cholesterol* Fluorouridine* Phosphorothioate
    0
    1 * 2,3,4,14,15,16,17 * 15,16,17
    0
    Phosphate; Base; Phosphate
    0
    48 percent target mRNA inhibition
    23135004
    SM2473
    GAGGCUGGGAUGCCUUUTT
    AAAGGCAUCCCAGCCUCCGTT
    Cholesterol* Fluorouridine* Phosphorothioate
    0
    1 * 6,11,15,16,17 *19
    0
    Phosphate; Base; Phosphate
    0
    37 percent target mRNA inhibition
    23135004
    SM2474
    GAGGCUGGGAUGCCUUUTT
    AAAGGCAUCCCAGCCUCCGTT
    Cholesterol* Fluorouridine* Phosphorothioate
    0
    1 * 15,16,17 * 1,2,19
    0
    Phosphate; Base; Phosphate
    0
    43 percent target mRNA inhibition
    23135004
    SM2475
    GAGGCUGGGAUGCCUUUTT
    AAAGGCAUCCCAGCCUCCGTT
    Cholesterol* Fluorouridine* Phosphorothioate
    0
    1 * 6,11,15,16,17 * 2,3,19
    0
    Phosphate; Base; Phosphate
    0
    52 percent target mRNA inhibition
    23135004