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Note: (i) 0 indicates modification in opposite strand. (ii) Multiple modifications are separated bt asterisk (*).

• By modification in sense strand


• By modification position in sense strand


• By modification in antisense strand


• By modification position in antisense strand


• Reference
Total number of Results for 1,2,3,4,16,17,18,19 are 14
Results from 0 - 25


SMDBid	siRNA (sense/antisense) 5'>3'	Modification (sense/antisense)	Position (sense/antisense)	Modified component (sense/antisense)	Efficacy (%)	Reference
SM4880	CGUACGCGGAAUACUUCGATT UCGAAGUAUUCCGCGUACGTT	4-Thioribose 0	1,2,3,4,16,17,18,19 0	Sugar 0	94.7 percent target mRNA inhibition	17150641
SM4888	AAACAUGCAGAAAAUGCUGTT CAGCAUUUUCUGCAUGUUUTT	4-Thioribose 0	1,2,3,4,16,17,18,19 0	Sugar 0	79.1 percent target mRNA inhibition	17150641
SM4901	CGUACGCGGAAUACUUCGATT UCGAAGUAUUCCGCGUACGTT	4-Thioribose 0	1,2,3,4,16,17,18,19 0	Sugar 0	94.7 percent target mRNA inhibition	17924376
SM4920	CGUACGCGGAAUACUUCGATT UCGAAGUAUUCCGCGUACGTT	4-Thioribose 4-Thioribose	1,2,3,4,16,17,18,19 1,2,3,4,16,17,18,19	Sugar Sugar	0 percent target mRNA inhibition	17924376
SM4923	CGUACGCGGAAUACUUCGATT UCGAAGUAUUCCGCGUACGTT	4-Thioribose 4-Thioribose	1,2,3,4,16,17,18,19 18,19	Sugar Sugar	92 percent target mRNA inhibition	17924376
SM4926	CGUACGCGGAAUACUUCGATT UCGAAGUAUUCCGCGUACGTT	4-Thioribose 4-Thioribose	1,2,3,4,16,17,18,19 16,17,18,19	Sugar Sugar	88.1 percent target mRNA inhibition	17924376
SM4930	CGUACGCGGAAUACUUCGATT UCGAAGUAUUCCGCGUACGTT	4-Thioribose 4-Thioribose	1,2,3,4,16,17,18,19 1,2,18,19	Sugar Sugar	87.7 percent target mRNA inhibition	17924376
SM4935	AAACAUGCAGAAAAUGCUGTT CAGCAUUUUCUGCAUGUUUTT	4-Thioribose 0	1,2,3,4,16,17,18,19 0	Sugar 0	79.1 percent target mRNA inhibition	17924376
SM4942	AAACAUGCAGAAAAUGCUGTT CAGCAUUUUCUGCAUGUUUTT	4-Thioribose 4-Thioribose	1,2,3,4,16,17,18,19 18,19	Sugar Sugar	85.5 percent target mRNA inhibition	17924376
SM4946	AAACAUGCAGAAAAUGCUGTT CAGCAUUUUCUGCAUGUUUTT	4-Thioribose 4-Thioribose	1,2,3,4,16,17,18,19 16,17,18,19	Sugar Sugar	91 percent target mRNA inhibition	17924376
SM4950	AAACAUGCAGAAAAUGCUGTT CAGCAUUUUCUGCAUGUUUTT	4-Thioribose 4-Thioribose	1,2,3,4,16,17,18,19 1,2,18,19	Sugar Sugar	66.3 percent target mRNA inhibition	17924376
SM4952	AAACAUGCAGAAAAUGCCUTT CAGCAUUUUCUGCAUGUUUTT	4-Thioribose 4-Thioribose	1,2,3,4,16,17,18,19 18,19	Sugar Sugar	87.7 percent target mRNA inhibition	17924376
SM4953	AAACAUGCAGAAAAUGCCUTT CAGCAUUUUCUGCAUGUUUTT	4-Thioribose 4-Thioribose	1,2,3,4,16,17,18,19 16,17,18,19	Sugar Sugar	87.3 percent target mRNA inhibition	17924376
SM4954	AAACAUGCAGAAAAUACCUTT CAGCAUUUUCUGCAUGUUUTT	4-Thioribose 4-Thioribose	1,2,3,4,16,17,18,19 1,2,18,19	Sugar Sugar	80.8 percent target mRNA inhibition	17924376