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Note: (i) 0 indicates modification in opposite strand. (ii) Multiple modifications are separated bt asterisk (*).
- By modification in sense strand
- By modification position in sense strand
- By modification in antisense strand
- By modification position in antisense strand
- Reference
Total number of Results for 4,6,7,14,15,19 are 4
Results from 0 - 25
SMDBid | siRNA (sense/antisense) 5'>3' | Modification (sense/antisense) | Position (sense/antisense) |
Modified component (sense/antisense) |
Efficacy (%) | Reference |
SM3017 |
GUUCACCUUGAUGCCGUUCUU GAACGGCAUCAAGGUGAACUU |
Phosphorothioate 0 |
4,6,7,14,15,19 0 |
Phosphate 0 |
85 percent target mRNA inhibition | 15545637 |
SM3018 |
GUUCACCUUGAUGCCGUUCUU GAACGGCAUCAAGGUGAACUU |
Boranophosphate 0 |
4,6,7,14,15,19 0 |
Phosphate 0 |
98 percent target mRNA inhibition | 15545637 |
SM3025 |
GUUCACCUUGAUGCCGUUCUU GAACGGCAUCAAGGUGAACUU |
Boranophosphate Boranophosphate |
4,6,7,14,15,19 4,7,10,19 |
Phosphate Phosphate |
90 percent target mRNA inhibition | 15545637 |
SM3029 |
GUUCACCUUGAUGCCGUUCUU GAACGGCAUCAAGGUGAACUU |
Boranophosphate Boranophosphate |
4,6,7,14,15,19 2,3,4,7,8,9,10,11,12,15,17,18,19,20,21 |
Phosphate Phosphate |
82 percent target mRNA inhibition | 15545637 |