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Page - 1 of 1 HIVsir ID HIV Strain NCBI Accession Target Gene Position of siRNA target Sense Sequence of siRNA Efficacy (%) GC Content (%) Cell line PubMed 1085 HIV-1(P90) K02013 Int 4962 AAGGUGAAGGGGCAGUAGUAA 71.00 38 293 T 15750613 1517 HIV-1 (NL4-3) AF324493 Nef 350 CACAAGGCUACUUCCCUGAU 71.10 40 HEK 293a 19497094 1303 95MM-yIDU106 N/A Pol 4888 UUCAAAAUUUUCGGGUUUAUU 71.60 19 Hela 17996047 1538 HIV-1 (LAI) K02013 LTR 5551 AUGGCAGGAAGAAGCGGAG 72.00 46 C33A 20188764 1415 HIV-1 (LAI) K02013 Pol 4542 AAGGUGAAGGGGCAGUAGU 72.00 42 293 T 19384894 1386 HIV-1 (LAI) K02013 Gag N/A GAAGAAAUGAUGACAGCA 73.00 30 293 T 18346971 1102 HIV-1 C K03455 Gag 792 GGGUGCGAGAGCGUCAAUA 73.00 46 HEK 293T 16706616 1439 HIV-1 (NL4-3) AF324493 Gag 578 GACAUCAAGCAGCCAUGCAA 73.20 40 HEK 293a 19497094 1354 93JP-NH1 AB052995 Pol 2486 ACCUACACCUGUCAACAUAAU 73.50 31 Hela 17996047 1481 HIV-1 (NL4-3) AF324493 Tat 132 CAUCUCCUAUGGCAGGAAGAA 73.80 38 HEK 293a 19497094 1375 HIV-1 (NL4-3) AF324493 Gag 8120 AGAAGGAUGUCAACAAAUA 74.00 25 U87.CD4.CXCR4 18199654 1132 HIV-1 (LAI) K02013 Gag 1366 AAGAAAUGAUGACAGCAUG 74.00 29 293 T 16959541 1161 HIV-1 (LAI) K02013 Pol 4391 UACAGUGCAGGGGAAAGAA 74.00 38 293 T 16959541 1586 CN54 AX149771 vif K*5195 GUUCAGAAGUACACAUCCC 75.00 38 Hela 15831707 1576 HIV-1(BAL) K02013 rev K*8485 GGCACUUAUCUGGGACGAU 75.00 42 Hela 15831707 1521 HIV-1 (LAI) K02013 Tat/Rev 5551 AUGGCAGGAAGAAGCGGAG 75.00 46 293 T 19672247 1013 HIV-1 (IIIB) EU541617 Gag K*1475 GAGAACCAAGGGGAAGUGACA 75.00 42 293 T 12391237 1384 HIV-1 (LAI) K02013 Pol N/A UAAUGAUGACGGGGAAGU 75.00 35 293 T 18346971 1134 HIV-1 (LAI) K02013 Gag 1624 AGGCUAAUUUUUUAGGGAA 75.00 25 293 T 16959541 1360 93JP-NH1 AB052995 Pol 4373 AGCCAUGCAUGGACAAGUAGA 75.00 38 Hela 17996047

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