ASPsiRNA ID | Pairing of target region (top) and ASP-siRNA (bottom) | Efficacy (mut)(%) | Efficacy (wt) (%) | Diff | Gene | Disease | Mutation | RefSNP | Analysis | Pubmed ID |
---|---|---|---|---|---|---|---|---|---|---|
ASPsiRNA ID | Mutant allele/ASP-siRNA | Efficacy for mutant(%) |
Efficacy for wild (%) |
Relative Difference (%) | Gene | Disease | Mutation | RefSNP | Analysis | Pubmed ID |
aspsirna1817 | AAGCAGCACAAUGAUGAGCGC UUCGUCGUGUUACUACUCGCG |
NA | 75 | NA | Fen1 | Werner syndrome | NA | NA | ||
aspsirna1818 | AAGCAGCACAAUGACGAGUGC UUCGUCGUGUUACUGCUCACG |
NA | 38 | NA | Fen1 | Werner syndrome | NA | NA | ||
aspsirna1819 | AAGCAGCACAACGAUGAGUGC UUCGUCGUGUUGCUACUCACG |
NA | 70 | NA | Fen1 | Werner syndrome | NA | NA | ||
aspsirna1820 | AAGCAGCACAAUGAUGAGUAC UUCGUCGUGUUACUACUCAUG |
NA | 60 | NA | Fen1 | Werner syndrome | NA | NA | ||
aspsirna1821 | AAGCAGCACAAUGAUAAGUGC UUCGUCGUGUUACUAUUCACG |
NA | 22 | NA | Fen1 | Werner syndrome | NA | NA | ||
aspsirna1822 | AAGCAGCACAAUAAUGAGUGC UUCGUCGUGUUAUUACUCACG |
NA | 23 | NA | Fen1 | Werner syndrome | NA | NA | ||
aspsirna1823 | AAGCAACACAAUGAUGAGUGC UUCGUUGUGUUACUACUCACG |
NA | 55 | NA | Fen1 | Werner syndrome | NA | NA | ||
aspsirna1824 | AAACAGCACAAUGAUGAGUGC UUUGUCGUGUUACUACUCACG |
NA | 75 | NA | Fen1 | Werner syndrome | NA | NA | ||
aspsirna1825 | AAGCAGCACAAUGACGAGCGC UUCGUCGUGUUACUGCUCGCG |
NA | 22 | NA | Fen1 | Werner syndrome | NA | NA | ||
aspsirna1826 | AAGCAGCACAACGACGAGUGC UUCGUCGUGUUGCUGCUCACG |
NA | 38 | NA | Fen1 | Werner syndrome | NA | NA | ||
aspsirna1827 | AAGCAGCACAAUGACGAGCAC UUCGUCGUGUUACUGCUCGUG |
NA | 22 | NA | Fen1 | Werner syndrome | NA | NA | ||
aspsirna1828 | AAGCAGCACAACGACGAGCGC UUCGUCGUGUUGCUGCUCGCG |
NA | 20 | NA | Fen1 | Werner syndrome | NA | NA | ||
aspsirna1829 | AAACAGCACAAUGACGAGCGC UUUGUCGUGUUACUGCUCGCG |
NA | 75 | NA | Fen1 | Werner syndrome | NA | NA | ||
aspsirna1830 | AAGCAGCACAAUGAUGAGUGU UUCGUCGUGUUACUACUCACA |
NA | 72 | NA | Fen1 | Werner syndrome | NA | NA | ||
aspsirna1831 | AAGCAGCACAAUGAUGAGUGG UUCGUCGUGUUACUACUCACC |
NA | 72 | NA | Fen1 | Werner syndrome | NA | NA | ||
aspsirna1832 | AAGCAGCACAAUGAUGAGUGA UUCGUCGUGUUACUACUCACU |
NA | 40 | NA | Fen1 | Werner syndrome | NA | NA | ||
aspsirna1833 | AAGCAGCACAAUGAUGAGGGC UUCGUCGUGUUACUACUCCCG |
NA | 55 | NA | Fen1 | Werner syndrome | NA | NA | ||
aspsirna1834 | AAGCAGCACAAUGAGGAGUGC UUCGUCGUGUUACUCCUCACG |
NA | 72 | NA | Fen1 | Werner syndrome | NA | NA | ||
aspsirna1835 | CCCCCUACCUGUGGACAUGGU GGGGGAUGGACACCUGUACCA |
NA | 70 | NA | Aqp4 | Brain edema | NA | NA | ||
aspsirna1836 | UAUGUCCACAGGUAGGGGGUU AUACAGGUGUCCAUCCCCCAA |
NA | 25 | NA | Aqp4 | Brain edema | NA | NA | ||
aspsirna1837 | CCCCCUACCUGUGGACAUGGU GGGGGAUGGACACCUGUACCA |
NA | 32 | NA | Aqp4 | Brain edema | NA | NA | ||
aspsirna1838 | CCUCACUGCUGGCCAUGGACU GGAGUGACGACCGGUACCUGA |
NA | 29 | NA | Aqp4 | Brain edema | NA | NA | ||
aspsirna1839 | CCUCACUGCUGGCCAUGGGCU GGAGUGACGACCGGUACCCGA |
NA | 31 | NA | Aqp4 | Brain edema | NA | NA | ||
aspsirna1840 | CCUCACUGCUGGCCAUGGACU GGAGUGACGACCGGUACCUGA |
NA | 22 | NA | Aqp4 | Brain edema | NA | NA | ||
aspsirna1841 | UGGCCAUGGGCUCCUGGUAGA ACCGGUACCCGAGGACCAUCU |
10 | 42 | -32 | Aqp4 | Brain edema | NA | NA | ||
aspsirna1842 | UGGCCAUGGGCUCCUGGUGGA ACCGGUACCCGAGGACCACCU |
80 | 30 | 50 | Aqp4 | Brain edema | NA | NA | ||
aspsirna1843 | UGGCCAUGGGCUCCUGGUAGA ACCGGUACCCGAGGACCAUCU |
23 | 50 | -27 | Aqp4 | Brain edema | NA | NA | ||
aspsirna1844 | CCAGCAUGAAUCCAGCUCAAU GGUCGUACUUAGGUCGAGUUA |
15 | 65 | -50 | Aqp4 | Brain edema | NA | NA | ||
aspsirna1845 | CCAGCAUGAAUCCAGCUCGAU GGUCGUACUUAGGUCGAGCUA |
5 | 55 | -50 | Aqp4 | Brain edema | NA | NA | ||
aspsirna1846 | CCAGCAUGAAUCCAGCUCAAU GGUCGUACUUAGGUCGAGUUA |
60 | 40 | 20 | Aqp4 | Brain edema | NA | NA | ||
aspsirna1847 | AGUUAUCAUGGGAAACUGAGA UCAAUAGUACCCUUUGACUCU |
26 | 58 | -32 | Aqp4 | Brain edema | NA | NA | ||
aspsirna1848 | AGUUAUCAUGGGAAACUGGGA UCAAUAGUACCCUUUGACCCU |
8 | 45 | -37 | Aqp4 | Brain edema | NA | NA | ||
aspsirna1849 | AGUUAUCAUGGGAAACUGAGA UCAAUAGUACCCUUUGACUCU |
23 | 30 | -7 | Aqp4 | Brain edema | NA | NA | ||
aspsirna1850 | CACUGGAUAUAUUGGGUUAGA GUGACCUAUAUAACCCAAUCU |
80 | 74 | 6 | Aqp4 | Brain edema | NA | NA | ||
aspsirna1851 | CACUGGAUAUAUUGGGUUGGA GUGACCUAUAUAACCCAACCU |
78 | 68 | 10 | Aqp4 | Brain edema | NA | NA | ||
aspsirna1852 | CACUGGAUAUAUUGGGUUAGA GUGACCUAUAUAACCCAAUCU |
22 | 52 | -30 | Aqp4 | Brain edema | NA | NA | ||
aspsirna1853 | GGGAGCUACAUGGAGGUGAAG CCCUCGAUGUACCUCCACUUC |
80 | 55 | 25 | Aqp4 | Brain edema | NA | NA | ||
aspsirna1854 | GGGAGCUACAUGGAGGUGGAG CCCUCGAUGUACCUCCACCUC |
60 | 50 | 10 | Aqp4 | Brain edema | NA | NA | ||
aspsirna1855 | GGGAGCUACAUGGAGGUGAAG CCCUCGAUGUACCUCCACUUC |
50 | 52 | -2 | Aqp4 | Brain edema | NA | NA | ||
aspsirna1856 | GACUUGAUCCUGAAGCCCAGG CUGAACUAGGACUUCGGGUCC |
70 | 83 | -13 | Aqp4 | Brain edema | NA | NA | ||
aspsirna1857 | GACUUGAUCCUGAAGCCCGGG CUGAACUAGGACUUCGGGCCC |
60 | 76 | -16 | Aqp4 | Brain edema | NA | NA | ||
aspsirna1858 | GACUUGAUCCUGAAGCCCAGG CUGAACUAGGACUUCGGGUCC |
10 | 90 | -80 | Aqp4 | Brain edema | NA | NA | ||
aspsirna1859 | GGACUCGUCUGGAGAGGUAUU CCUGAGCAGACCUCUCCAUAA |
25 | 93 | -68 | Aqp4 | Brain edema | NA | NA | ||
aspsirna1860 | GGACUCGUCUGGAGAGGUGUA CCUGAGCAGACCUCUCCACAU |
15 | 89 | -74 | Aqp4 | Brain edema | NA | NA | ||
aspsirna1861 | GGACUCGUCUGGAGAGGUAUU CCUGAGCAGACCUCUCCAUAA |
50 | 88 | -38 | Aqp4 | Brain edema | NA | NA | ||
aspsirna1862 | AACCGGAGCCAAGUGGAGCCA UUGGCCUCGGUUCACCUCGGU |
88 | 85 | 3 | Aqp4 | Brain edema | NA | NA | ||
aspsirna1863 | AACCGGAGCCAAGUGGAGACA UUGGCCUCGGUUCACCUCUGU |
93 | 82 | 11 | Aqp4 | Brain edema | NA | NA | ||
aspsirna1864 | AACCGGAGCCAAGUGGAGCCA UUGGCCUCGGUUCACCUCGGU |
70 | 15 | 55 | Aqp4 | Brain edema | NA | NA | ||
aspsirna1865 | UGGCCAUGGGCUCCUGGUAGA ACCGGUACCCGAGGACCAUCU |
10 | 42 | -32 | Aqp4 | Brain edema | NA | NA | ||
aspsirna1866 | UGGCCAUGGGCUCCUGGUGGA ACCGGUACCCGAGGACCACCU |
80 | 30 | 50 | Aqp4 | Brain edema | NA | NA | ||
aspsirna1867 | UGGCCAUGGGCUCCUGGUAGA ACCGGUACCCGAGGACCAUCU |
23 | 50 | -27 | Aqp4 | Brain edema | NA | NA | ||
aspsirna1868 | CCAGCAUGAAUCCAGCUCAAU GGUCGUACUUAGGUCGAGUUA |
15 | 65 | -50 | Aqp4 | Brain edema | NA | NA | ||
aspsirna1869 | CCAGCAUGAAUCCAGCUCGAU GGUCGUACUUAGGUCGAGCUA |
5 | 55 | -50 | Aqp4 | Brain edema | NA | NA | ||
aspsirna1870 | CCAGCAUGAAUCCAGCUCAAU GGUCGUACUUAGGUCGAGUUA |
60 | 40 | 20 | Aqp4 | Brain edema | NA | NA | ||
aspsirna1871 | AGUUAUCAUGGGAAACUGAGA UCAAUAGUACCCUUUGACUCU |
26 | 58 | -32 | Aqp4 | Brain edema | NA | NA | ||
aspsirna1872 | AGUUAUCAUGGGAAACUGGGA UCAAUAGUACCCUUUGACCCU |
8 | 45 | -37 | Aqp4 | Brain edema | NA | NA | ||
aspsirna1873 | AGUUAUCAUGGGAAACUGAGA UCAAUAGUACCCUUUGACUCU |
23 | 30 | -7 | Aqp4 | Brain edema | NA | NA | ||
aspsirna1874 | CACUGGAUAUAUUGGGUUAGA GUGACCUAUAUAACCCAAUCU |
80 | 74 | 6 | Aqp4 | Brain edema | NA | NA | ||
aspsirna1875 | CACUGGAUAUAUUGGGUUGGA GUGACCUAUAUAACCCAACCU |
78 | 68 | 10 | Aqp4 | Brain edema | NA | NA | ||
aspsirna1876 | CACUGGAUAUAUUGGGUUAGA GUGACCUAUAUAACCCAAUCU |
22 | 52 | -30 | Aqp4 | Brain edema | NA | NA | ||
aspsirna1877 | GGGAGCUACAUGGAGGUGAAG CCCUCGAUGUACCUCCACUUC |
80 | 55 | 25 | Aqp4 | Brain edema | NA | NA | ||
aspsirna1878 | GGGAGCUACAUGGAGGUGGAG CCCUCGAUGUACCUCCACCUC |
60 | 50 | 10 | Aqp4 | Brain edema | NA | NA | ||
aspsirna1879 | GGGAGCUACAUGGAGGUGAAG CCCUCGAUGUACCUCCACUUC |
50 | 52 | -2 | Aqp4 | Brain edema | NA | NA | ||
aspsirna1880 | GACUUGAUCCUGAAGCCCAGG CUGAACUAGGACUUCGGGUCC |
70 | 83 | -13 | Aqp4 | Brain edema | NA | NA | ||
aspsirna1881 | GACUUGAUCCUGAAGCCCGGG CUGAACUAGGACUUCGGGCCC |
60 | 76 | -16 | Aqp4 | Brain edema | NA | NA | ||
aspsirna1882 | GACUUGAUCCUGAAGCCCAGG CUGAACUAGGACUUCGGGUCC |
10 | 90 | -80 | Aqp4 | Brain edema | NA | NA | ||
aspsirna1883 | AACCGGAGCCAAGUGGAGCCA UUGGCCUCGGUUCACCUCGGU |
88 | 85 | 3 | Aqp4 | Brain edema | NA | NA | ||
aspsirna1884 | AACCGGAGCCAAGUGGAGACA UUGGCCUCGGUUCACCUCUGU |
93 | 82 | 11 | Aqp4 | Brain edema | NA | NA | ||
aspsirna1885 | AACCGGAGCCAAGUGGAGCCA UUGGCCUCGGUUCACCUCGGU |
70 | 15 | 55 | Aqp4 | Brain edema | NA | NA |