ASPsiRNA ID | Pairing of target region (top) and ASP-siRNA (bottom) | Efficacy (mut)(%) | Efficacy (wt) (%) | Diff | Gene | Disease | Mutation | RefSNP | Analysis | Pubmed ID |
---|---|---|---|---|---|---|---|---|---|---|
ASPsiRNA ID | Mutant allele/ASP-siRNA | Efficacy for mutant(%) |
Efficacy for wild (%) |
Relative Difference (%) | Gene | Disease | Mutation | RefSNP | Analysis | Pubmed ID |
aspsirna0971 | CAGCAGCAGCAGCAGCAGCAG GUCGUCGUCGUCGUCGUCGUC |
75 | 60 | 15 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs19392295 | ||
aspsirna0972 | CAGCAGCAGCAGCAGCAGCAG GUCGUCGUCGUCGUCGUCGUC |
50 | 39 | 11 | ATXN1 | Spino Cerebellar Ataxia type-1 (SCA-1) | c.589_591CAG(36_38) | rs19392292 | ||
aspsirna0973 | CAGCAGCAGCAGCAGCAGCAG GUCGUCGUCGUCGUCGUCGUC |
70 | 30 | 40 | ATXN3 | Parkinsons disease (PD) | c.209_211CAG(8_36),(p.Gln298_Gln305=) | rs19392292 | ||
aspsirna0974 | GUCGUCGUCGUCGUCGUCGUC CAGCAGCAGCAGCAGCAGCAG |
68 | 15 | 53 | RPL14 | Neurological disorder | NA | NA | ||
aspsirna0975 | GUCGUCGUCGUCGUCGUCGUC CAGCAGCAGCAGCAGCAGCAG |
65 | 20 | 45 | LRP8 | Neurological disorder | NA | NA | ||
aspsirna0976 | GUCGUCGUCGUCGUCGUCGUC CAGCAGCAGCAGCAGCAGCAG |
70 | 52 | 18 | EIF2AK1 | Neurological disorder | NA | NA | ||
aspsirna0977 | CAGCAGCAGCAGCAGCAGCAGCAGCAG GUCGUCGUCGUCGUCGUCGUCGUCGUC |
75 | 60 | 15 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs19392295 | ||
aspsirna0978 | CAGCAGCAGCAGCAGCAGCAGCAGCAG GUCGUCGUCGUCGUCGUCGUCGUCGUC |
56 | 39 | 17 | ATXN1 | Neurological disorder | c.589_591CAG(36_38) | rs19392292 | ||
aspsirna0979 | CAGCAGCAGCAGCAGCAGCAGCAGCAG GUCGUCGUCGUCGUCGUCGUCGUCGUC |
78 | 30 | 48 | ATXN3 | Parkinsons disease (PD) | c.209_211CAG(8_36),(p.Gln298_Gln305=) | rs19392292 | ||
aspsirna0980 | GUCGUCGUCGUCGUCGUCGUCGUCGUC CAGCAGCAGCAGCAGCAGCAGCAGCAG |
63 | 15 | 48 | RPL14 | Neurological disorder | NA | NA | ||
aspsirna0981 | GUCGUCGUCGUCGUCGUCGUCGUCGUC CAGCAGCAGCAGCAGCAGCAGCAGCAG |
60 | 20 | 40 | LRP8 | Neurological disorder | NA | NA | ||
aspsirna0982 | GUCGUCGUCGUCGUCGUCGUCGUCGUC CAGCAGCAGCAGCAGCAGCAGCAGCAG |
70 | 50 | 20 | EIF2AK1 | Neurological disorder | NA | NA | ||
aspsirna0983 | CAGCAGCAGCAGUAGCAGCAG GUCGUCGUCGUCAUCGUCGUC |
75 | 20 | 55 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs19392295 | ||
aspsirna0984 | CAGCAGCAGCAGCAGUAGCAG GUCGUCGUCGUCGUCAUCGUC |
60 | 23 | 37 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs19392295 | ||
aspsirna0985 | CAGCAGCAGCAGUAGUAGCAG GUCGUCGUCGUCAUCAUCGUC |
78 | 20 | 58 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs19392295 | ||
aspsirna0986 | UAGCAGCAGCAGCAGCAGUAG AUCGUCGUCGUCGUCGUCAUC |
60 | 45 | 15 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs19392295 | ||
aspsirna0987 | CAGCAGCAGCAGUAGCAGCAG GUCGUCGUCGUCAUCGUCGUC |
75 | 20 | 55 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs19392295 | ||
aspsirna0988 | CAGCAGCAGCAGCAGUAGCAG GUCGUCGUCGUCGUCAUCGUC |
60 | 23 | 37 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs19392295 | ||
aspsirna0989 | CAGCAGCAGCAGUAGUAGCAG GUCGUCGUCGUCAUCAUCGUC |
78 | 20 | 58 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs19392295 | ||
aspsirna0990 | UAGCAGCAGCAGCAGCAGUAG AUCGUCGUCGUCGUCGUCAUC |
60 | 45 | 15 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs19392295 | ||
aspsirna0991 | CAGCAGCAGCAGCAGU GUCGUCGUCGUCGUCAUCGUC |
60 | 25 | 35 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs19392295 | ||
aspsirna0992 | CAGCAGCAGCAGUAGU GUCGUCGUCGUCAUCAUCGUC |
78 | 25 | 53 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs19392295 | ||
aspsirna0993 | CAGCAGCAGCAGCAGUA GUCGUCGUCGUCGUCAUCGUC |
60 | 25 | 35 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs19392295 | ||
aspsirna0994 | CAGCAGCAGCAGUAGUA GUCGUCGUCGUCAUCAUCGUC |
78 | 25 | 53 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs19392295 | ||
aspsirna0995 | CAGCAGCAGCAGCAGU GUCGUCGUCGUCGUCAUCGUC |
60 | 25 | 35 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs19392295 | ||
aspsirna0996 | CAGCAGCAGCAGUAGU GUCGUCGUCGUCAUCAUCGUC |
70 | 25 | 45 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs19392295 | ||
aspsirna0997 | CAGCAGCAGCAGCAGUA GUCGUCGUCGUCGUCAUCGUC |
60 | 30 | 30 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs19392295 | ||
aspsirna0998 | CAGCAGCAGCAGUAGUA GUCGUCGUCGUCAUCAUCGUC |
78 | 20 | 58 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs19392295 |