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Note: (i) 0 indicates modification in opposite strand. (ii) Multiple modifications are separated bt asterisk (*).
  • By modification in sense strand

  • By modification position in sense strand

  • By modification in antisense strand

  • By modification position in antisense strand

  • Reference
    • Total number of Results for 21 are 161
    Results from 125 - 150
    SMDBidsiRNA (sense/antisense) 5'>3'Modification (sense/antisense)Position (sense/antisense) Modified component (sense/antisense) Efficacy (%)Reference
    SM2752
    UCGAAGUAUUCCGCGUACGTT
    CGUACGCGGAAUACUUCGATT
    Trifluoromethylbenzene
    0
    21
    0
    Sugar
    0
    80 percent target mRNA inhibition
    20485810
    SM2753
    UCGAAGUAUUCCGCGUACGTT
    CGUACGCGGAAUACUUCGATT
    Fluorobenzene
    0
    21
    0
    Sugar
    0
    80 percent target mRNA inhibition
    20485810
    SM2754
    UCGAAGUAUUCCGCGUACGTT
    CGUACGCGGAAUACUUCGATT
    Methyl
    0
    21
    0
    Sugar
    0
    79 percent target mRNA inhibition
    20485810
    SM2756
    UCGAAGUAUUCCGCGUACGTT
    CGUACGCGGAAUACUUCGATT
    Pyrene modification
    0
    21
    0
    Sugar
    0
    74 percent target mRNA inhibition
    20485810
    SM2757
    UCGAAGUAUUCCGCGUACGTT
    CGUACGCGGAAUACUUCGATT
    Anthracene
    0
    21
    0
    Sugar
    0
    72 percent target mRNA inhibition
    20485810
    SM2758
    UCGAAGUAUUCCGCGUACGTT
    CGUACGCGGAAUACUUCGATT
    Naphthalene modification
    0
    21
    0
    Sugar
    0
    70 percent target mRNA inhibition
    20485810
    SM2759
    UCGAAGUAUUCCGCGUACGTT
    CGUACGCGGAAUACUUCGATT
    Trifluoromethylbenzene
    0
    21
    0
    Sugar
    0
    72 percent target mRNA inhibition
    20485810
    SM2760
    UCGAAGUAUUCCGCGUACGTT
    CGUACGCGGAAUACUUCGATT
    Fluorobenzene
    0
    21
    0
    Sugar
    0
    72 percent target mRNA inhibition
    20485810
    SM2761
    UCGAAGUAUUCCGCGUACGTT
    CGUACGCGGAAUACUUCGATT
    Methyl
    0
    21
    0
    Sugar
    0
    75 percent target mRNA inhibition
    20485810
    SM2763
    UCGAAGUAUUCCGCGUACGTT
    CGUACGCGGAAUACUUCGATT
    Pyrene modification
    0
    21
    0
    Sugar
    0
    66 percent target mRNA inhibition
    20485810
    SM2764
    UCGAAGUAUUCCGCGUACGTT
    CGUACGCGGAAUACUUCGATT
    Anthracene
    0
    21
    0
    Sugar
    0
    65 percent target mRNA inhibition
    20485810
    SM2765
    UCGAAGUAUUCCGCGUACGTT
    CGUACGCGGAAUACUUCGATT
    Naphthalene modification
    0
    21
    0
    Sugar
    0
    61 percent target mRNA inhibition
    20485810
    SM2766
    UCGAAGUAUUCCGCGUACGTT
    CGUACGCGGAAUACUUCGATT
    Trifluoromethylbenzene
    0
    21
    0
    Sugar
    0
    67 percent target mRNA inhibition
    20485810
    SM2767
    UCGAAGUAUUCCGCGUACGTT
    CGUACGCGGAAUACUUCGATT
    Fluorobenzene
    0
    21
    0
    Sugar
    0
    66 percent target mRNA inhibition
    20485810
    SM2768
    UCGAAGUAUUCCGCGUACGTT
    CGUACGCGGAAUACUUCGATT
    Methyl
    0
    21
    0
    Sugar
    0
    62 percent target mRNA inhibition
    20485810
    SM2770
    UCGAAGUAUUCCGCGUACGTT
    CGUACGCGGAAUACUUCGATT
    Pyrene modification
    0
    21
    0
    Sugar
    0
    72 percent target mRNA inhibition
    20485810
    SM2771
    UCGAAGUAUUCCGCGUACGTT
    CGUACGCGGAAUACUUCGATT
    Anthracene
    0
    21
    0
    Sugar
    0
    72 percent target mRNA inhibition
    20485810
    SM2772
    UCGAAGUAUUCCGCGUACGTT
    CGUACGCGGAAUACUUCGATT
    Naphthalene modification
    0
    21
    0
    Sugar
    0
    74 percent target mRNA inhibition
    20485810
    SM2773
    UCGAAGUAUUCCGCGUACGTT
    CGUACGCGGAAUACUUCGATT
    Trifluoromethylbenzene
    0
    21
    0
    Sugar
    0
    72 percent target mRNA inhibition
    20485810
    SM2774
    UCGAAGUAUUCCGCGUACGTT
    CGUACGCGGAAUACUUCGATT
    Fluorobenzene
    0
    21
    0
    Sugar
    0
    72 percent target mRNA inhibition
    20485810
    SM2775
    UCGAAGUAUUCCGCGUACGTT
    CGUACGCGGAAUACUUCGATT
    Methyl
    0
    21
    0
    Sugar
    0
    71 percent target mRNA inhibition
    20485810
    SM2912
    GACGUAAACGGCCACAAGUUUU
    ACUUGUGGCCGUUUACGUCGUU
    UnLocked nucleic acid
    Unlocked nucleic acid
    21
    21
    Sugar
    Sugar
    High target mRNA inhibition efficacy
    21687525
    SM2913
    GACGUAAACGGCCACAAGUUUU
    ACUUGUGGCCGUUUACGUCGCU
    UnLocked nucleic acid
    Unlocked nucleic acid * Locked nucleic acid
    21
    6 * 20,21
    Sugar
    Sugar
    High target mRNA inhibition efficacy
    21687525
    SM2920
    GACGUAAACGGCCACAAGUUUU
    ACUUGUGGCCGUUUACGUCGUU
    UnLocked nucleic acid
    Unlocked nucleic acid
    21
    21
    Sugar
    Sugar
    High target mRNA inhibition efficacy
    21687525
    SM2921
    GACGUAAACGGCCACAAGUUUU
    ACUUGUGGCCGUUUACGUCGCU
    UnLocked nucleic acid
    Unlocked nucleic acid * Locked nucleic acid
    21
    6 * 20,21
    Sugar
    Sugar
    High target mRNA inhibition efficacy
    21687525