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Note: (i) 0 indicates modification in opposite strand. (ii) Multiple modifications are separated bt asterisk (*).

• By modification in sense strand


• By modification position in sense strand


• By modification in antisense strand


• By modification position in antisense strand


• Reference
Total number of Results for 9 are 24
Results from 0 - 25


SMDBid	siRNA (sense/antisense) 5'>3'	Modification (sense/antisense)	Position (sense/antisense)	Modified component (sense/antisense)	Efficacy (%)	Reference
SM2777	CUUACGCUGAGUACUUCGATT TCGAAGUACUCAGCGUAAGTT	2,4-Difluorotoluene-2-Deoxyribonucleotide 0	9 0	Base 0	NA	20610434
SM2781	CUUACGCUGAGUACUUCGATT TCGAAGUACUCAGCGUAAGTT	2,4-Difluorotoluene 0	9 0	Base 0	NA	20610434
SM2785	CUUACGCUGAGUACUUCGATT TCGAAGUACUCAGCGUAAGTT	5-Nitroindole-2-Deoxyribonucleotide 0	9 0	Base 0	NA	20610434
SM2789	CUUACGCUGAGUACUUCGATT TCGAAGUACUCAGCGUAAGTT	5-Nitroindoleribonucleotide 0	9 0	Base 0	NA	20610434
SM2793	CUUACGCUGAGUACUUCGATT TCGAAGUACUCAGCGUAAGTT	2-Deoxynebularine 0	9 0	Base 0	NA	20610434
SM2797	CUUACGCUGAGUACUUCGATT TCGAAGUACUCAGCGUAAGTT	Nebularine 0	9 0	Base 0	NA	20610434
SM2801	CUUACGCUGAGUACUUCGATT TCGAAGUACUCAGCGUAAGTT	2-Deoxy-2-Aminopurine-2-Deoxyribonucleotide 0	9 0	Base 0	NA	20610434
SM2805	CUUACGCUGAGUACUUCGATT TCGAAGUACUCAGCGUAAGTT	2-Aminopurineribonucleotide 0	9 0	Base 0	NA	20610434
SM2809	CUUACGCUGAGUACUUCGATT TCGAAGUACUCAGCGUAAGTT	2-Deoxyinosine 0	9 0	Base 0	NA	20610434
SM2813	CUUACGCUGAGUACUUCGATT TCGAAGUACUCAGCGUAAGTT	Inosine 0	9 0	Base 0	NA	20610434
SM2817	AUUACGCUGAGUACUUCGATT UCGAAGUACUCAGCGUAAUTT	Abasic(2-hydroxymethyl-tetrahydrofuran-3-ol) 0	9 0	Base 0	NA	20610434
SM2828	CUUACGCUGAGUACUUCGAAA UCGAAGUACUCAGCGUAAGUG	2-O-Methyl 0	9 0	Sugar 0	IC-50 = 0.146 nM for target mRNA	20610434
SM2829	CUUACGCUGAGUACUUCGAAA UCGAAGUACUCAGCGUAAGUG	2-O-Methyl* Phosphorothioate 0	9 0	Sugar; Phosphate 0	IC-50 = 0.129 nM for target mRNA	20610434
SM2844	AAGUAAGGACCAGAGACAATT UUGUCUCUGGUCCUUACUUTT	2,4-difluorotoluene ribonucleotide 0	9 0	Base 0	IC-50 = 0.031 nM for target mRNA	20610434
SM3360	AGACGAGCUGAGCGAGAAGTT TTUCUGCUCGACUCGCUCUUC	2-Deoxy-2-fluorouridine 0	9 0	Sugar 0	NA	12834349
SM3514	GAAACUGGUACUUUCCCCCTT GGGGGAAAGUACCAGUUUCTT	2-Deoxy-2-Fluoro 2-Deoxy-2-Fluoro	9 10	Sugar Sugar	58 percent target mRNA inhibition	US20120088815A1, EP2415869A1
SM3670	AGCCCAGAUAGCUCUUCAGTT CUGAAGAGCUAUCUGGGCUTT	2-Deoxy-2-Fluoro 2-Deoxy-2-Fluoro	9 10	Sugar Sugar	69 percent target mRNA inhibition	US20120088815A1, EP2415869A1
SM3734	GGCCAAAGUAAUCGUGGUUTT AACCACGAUUACUUUGGCCTT	2-O-Methyl 2-O-Methyl	9 10	Sugar Sugar	85 percent target mRNA inhibition	US20120088815A1, EP2415869A1
SM3772	AGAGGACCUAGAAGGCGGCTT GCCGCCUUCUAGGUCCUCUTT	2-O-Methyl 2-O-Methyl	9 7,8,10,14,17,19	Sugar Sugar	72 percent target mRNA inhibition	US20120088815A1, EP2415869A1
SM3773	AGAGGACCUAGAAGGCGGCTT GCCGCCUUCUAGGUCCUCUTT	2-O-Methyl 2-O-Methyl	9 10	Sugar Sugar	89 percent target mRNA inhibition	US20120088815A1, EP2415869A1
SM3790	GAGGAAGAUGAGUUGUACCTT GGUACAACUCAUCUUCCUCTT	2-O-Methyl 2-O-Methyl	9 5,10	Sugar Sugar	77 percent target mRNA inhibition	US20120088815A1, EP2415869A1
SM4042	CCCUCCCCUGUCCCCGCUUTT AAGCGGGGACAGGGGAGGGTT	2-Deoxy-2-Fluoro 0	9 0	Sugar 0	73 percent target mRNA inhibition	US20120088815A1, EP2415869A1
SM4134	AACUCUACUGUGGAGUCGGTT CCGACUCCACAGUAGAGUUTT	2-Deoxy-2-Fluoro 2-Deoxy-2-Fluoro	9 8,13	Sugar Sugar	72 percent target mRNA inhibition	US20120088815A1, EP2415869A1
SM4142	GGAAGUCCACCUUCUCCGATT UCGGAGAAGGUGGACUUCCTT	2-O-Methyl 2-O-Methyl	9 11	Sugar Sugar	54 percent target mRNA inhibition	US20120088815A1, EP2415869A1