SMDBid | siRNA (sense/antisense) 5'>3' | Modification (sense/antisense) | Position (sense/antisense) |
Modified component (sense/antisense) |
Efficacy (%) | Reference |
SM3277 |
GUAUUGACAGCUAUUCGAATT UUCGAAUAGCUGUCAAUACTT |
Altritol nucleic acid 0 |
3,7 0 |
Sugar 0 |
NA | 17264131 |
SM3278 |
GUAUUGACAGCUAUUCGAATT UUCGAAUAGCUGUCAAUACTT |
Altritol nucleic acid 0 |
18 0 |
Sugar 0 |
NA | 17264131 |
SM3279 |
GUAUUGACAGCUAUUCGAATT UUCGAAUAGCUGUCAAUACTT |
Altritol nucleic acid 0 |
15 0 |
Sugar 0 |
44 percent target mRNA inhibition | 17264131 |
SM3280 |
GUAUUGACAGCUAUUCGAATT UUCGAAUAGCUGUCAAUACTT |
Altritol nucleic acid 0 |
12 0 |
Sugar 0 |
38 percent target mRNA inhibition | 17264131 |
SM3281 |
GUAUUGACAGCUAUUCGAATT UUCGAAUAGCUGUCAAUACTT |
Altritol nucleic acid 0 |
5 0 |
Sugar 0 |
42 percent target mRNA inhibition | 17264131 |
SM3282 |
GUAUUGACAGCUAUUCGAATT UUCGAAUAGCUGUCAAUACTT |
Altritol nucleic acid 0 |
2 0 |
Sugar 0 |
42 percent target mRNA inhibition | 17264131 |
SM3283 |
GUAUUGACAGCUAUUCGAATT UUCGAAUAGCUGUCAAUACTT |
Altritol nucleic acid 0 |
5,12,14,15 0 |
Sugar 0 |
47 percent target mRNA inhibition | 17264131 |
SM3284 |
GUAUUGACAGCUAUUCGAATT UUCGAAUAGCUGUCAAUACTT |
Altritol nucleic acid 0 |
3,5,9,12,15,18 0 |
Sugar 0 |
29 percent target mRNA inhibition | 17264131 |
SM3285 |
GUAUUGACAGCUAUUCGAATT UUCGAAUAGCUGUCAAUACTT |
Altritol nucleic acid 0 |
2,3,4,5,7,9,12,13,14,15,18,19 0 |
Sugar 0 |
29 percent target mRNA inhibition | 17264131 |
SM3286 |
GUAUUGACAGCUAUUCGAATT UUCGAAUAGCUGUCAAUACTT |
Altritol nucleic acid 0 |
5,9,11,14,17 0 |
Sugar 0 |
33 percent target mRNA inhibition | 17264131 |
SM3287 |
GUAUUGACAGCUAUUCGAATT UUCGAAUAGCUGUCAAUACTT |
Altritol nucleic acid 0 |
1,2,18,19 0 |
Sugar 0 |
53 percent target mRNA inhibition | 17264131 |
SM3288 |
GUAUUGACAGCUAUUCGAATT UUCGAAUAGCUGUCAAUACTT |
Altritol nucleic acid 0 |
9,10,11 0 |
Sugar 0 |
50 percent target mRNA inhibition | 17264131 |
SM3289 |
GUAUUGACAGCUAUUCGAATT UUCGAAUAGCUGUCAAUACTT |
Altritol nucleic acid 0 |
18 0 |
Sugar 0 |
46 percent target mRNA inhibition | 17264131 |
SM3290 |
GUAUUGACAGCUAUUCGAATT UUCGAAUAGCUGUCAAUACTT |
Altritol nucleic acid 0 |
4,5,6,7,8,9,10,11,12,13,14,15,16 0 |
Sugar 0 |
22 percent target mRNA inhibition | 17264131 |
SM3291 |
GUAUUGACAGCUAUUCGAATT UUCGAAUAGCUGUCAAUACTT |
Altritol nucleic acid 0 |
1 0 |
Sugar 0 |
33 percent target mRNA inhibition | 17264131 |
SM3292 |
GUAUUGACAGCUAUUCGAATT UUCGAAUAGCUGUCAAUACTT |
Altritol nucleic acid 0 |
1,2 0 |
Sugar 0 |
36 percent target mRNA inhibition | 17264131 |
SM3293 |
GUAUUGACAGCUAUUCGAATT UUCGAAUAGCUGUCAAUACTT |
0 Altritol nucleic acid |
0 18 |
0 Sugar |
76 percent target mRNA inhibition | 17264131 |
SM3294 |
GUAUUGACAGCUAUUCGAATT UUCGAAUAGCUGUCAAUACTT |
0 Altritol nucleic acid |
0 16 |
0 Sugar |
38 percent target mRNA inhibition | 17264131 |
SM3295 |
GUAUUGACAGCUAUUCGAATT UUCGAAUAGCUGUCAAUACTT |
0 Altritol nucleic acid |
0 17 |
0 Sugar |
46 percent target mRNA inhibition | 17264131 |
SM3296 |
GUAUUGACAGCUAUUCGAATT UUCGAAUAGCUGUCAAUACTT |
0 Altritol nucleic acid |
0 13 |
0 Sugar |
36 percent target mRNA inhibition | 17264131 |
SM3297 |
GUAUUGACAGCUAUUCGAATT UUCGAAUAGCUGUCAAUACTT |
0 Altritol nucleic acid |
0 11 |
0 Sugar |
36 percent target mRNA inhibition | 17264131 |
SM3298 |
GUAUUGACAGCUAUUCGAATT UUCGAAUAGCUGUCAAUACTT |
0 Altritol nucleic acid |
0 7 |
0 Sugar |
56 percent target mRNA inhibition | 17264131 |
SM3299 |
GUAUUGACAGCUAUUCGAATT UUCGAAUAGCUGUCAAUACTT |
0 Altritol nucleic acid |
0 2 |
0 Sugar |
41 percent target mRNA inhibition | 17264131 |
SM3300 |
GUAUUGACAGCUAUUCGAATT UUCGAAUAGCUGUCAAUACTT |
0 Altritol nucleic acid |
0 1,2 |
0 Sugar |
0 percent target mRNA inhibition | 17264131 |
SM3301 |
GUAUUGACAGCUAUUCGAATT UUCGAAUAGCUGUCAAUACTT |
0 Altritol nucleic acid |
0 9,10,11 |
0 Sugar |
12 percent target mRNA inhibition | 17264131 |