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Note: (i) 0 indicates modification in opposite strand. (ii) Multiple modifications are separated bt asterisk (*).
  • By modification in sense strand

  • By modification position in sense strand

  • By modification in antisense strand

  • By modification position in antisense strand

  • Reference
    • Total number of Results for 25233814 are 64
    Results from 0 - 25
    SMDBidsiRNA (sense/antisense) 5'>3'Modification (sense/antisense)Position (sense/antisense) Modified component (sense/antisense) Efficacy (%)Reference
    SM4232
    AACCUUACCCACCUCAUGUAUCU
    AGAUACAUGAGGUGGGUAAGGUU
    Serinol nucleic acid
    0
    1,2
    0
    Sugar
    0
    93 percent target mRNA inhibition
    25233814
    SM4233
    AACCUUACCCACCUCAUGUAUCU
    AGAUACAUGAGGUGGGUAAGGUU
    Serinol nucleic acid
    0
    22,23
    0
    Sugar
    0
    90 percent target mRNA inhibition
    25233814
    SM4234
    AACCUUACCCACCUCAUGUAUCU
    AGAUACAUGAGGUGGGUAAGGUU
    0
    Serinol nucleic acid
    0
    22,23
    0
    Sugar
    60 percent target mRNA inhibition
    25233814
    SM4235
    AACCUUACCCACCUCAUGUAUCU
    AGAUACAUGAGGUGGGUAAGGUU
    0
    Serinol nucleic acid
    0
    1,2
    0
    Sugar
    62 percent target mRNA inhibition
    25233814
    SM4236
    AACCUUACCCACCUCAUGUAUCU
    AGAUACAUGAGGUGGGUAAGGUU
    Serinol nucleic acid
    Serinol nucleic acid
    1,2
    22,23
    Sugar
    Sugar
    89 percent target mRNA inhibition
    25233814
    SM4237
    AACCUUACCCACCUCAUGUAUCU
    AGAUACAUGAGGUGGGUAAGGUU
    Serinol nucleic acid
    Serinol nucleic acid
    1,2
    1,2
    Sugar
    Sugar
    78 percent target mRNA inhibition
    25233814
    SM4238
    AACCUUACCCACCUCAUGUAUCU
    AGAUACAUGAGGUGGGUAAGGUU
    Serinol nucleic acid
    Serinol nucleic acid
    22,23
    22,23
    Sugar
    Sugar
    82 percent target mRNA inhibition
    25233814
    SM4239
    AACCUUACCCACCUCAUGUAUCU
    AGAUACAUGAGGUGGGUAAGGUU
    Serinol nucleic acid
    Serinol nucleic acid
    22,23
    1,2
    Sugar
    Sugar
    74 percent target mRNA inhibition
    25233814
    SM4240
    AACCUUACCCACCUCAUGUAUCU
    AGAUACAUGAGGUGGGUAAGGUU
    Serinol nucleic acid
    0
    1,2,22,23
    0
    Sugar
    0
    98 percent target mRNA inhibition
    25233814
    SM4241
    AACCUUACCCACCUCAUGUAUCU
    AGAUACAUGAGGUGGGUAAGGUU
    Serinol nucleic acid
    Serinol nucleic acid
    1,2,22,23
    22,23
    Sugar
    Sugar
    97 percent target mRNA inhibition
    25233814
    SM4242
    AACCUUACCCACCUCAUGUAUCU
    AGAUACAUGAGGUGGGUAAGGUU
    Serinol nucleic acid
    Serinol nucleic acid
    1,2,22,23
    1,2
    Sugar
    Sugar
    70 percent target mRNA inhibition
    25233814
    SM4243
    AACCUUACCCACCUCAUGUAUCU
    AGAUACAUGAGGUGGGUAAGGUU
    0
    Serinol nucleic acid
    0
    1,2,22,23
    0
    Sugar
    40 percent target mRNA inhibition
    25233814
    SM4244
    AACCUUACCCACCUCAUGUAUCU
    AGAUACAUGAGGUGGGUAAGGUU
    Serinol nucleic acid
    Serinol nucleic acid
    1,2
    1,2,22,23
    Sugar
    Sugar
    76 percent target mRNA inhibition
    25233814
    SM4245
    AACCUUACCCACCUCAUGUAUCU
    AGAUACAUGAGGUGGGUAAGGUU
    Serinol nucleic acid
    Serinol nucleic acid
    22,23
    1,2,22,23
    Sugar
    Sugar
    55 percent target mRNA inhibition
    25233814
    SM4246
    AACCUUACCCACCUCAUGUAUCU
    AGAUACAUGAGGUGGGUAAGGUU
    Serinol nucleic acid
    Serinol nucleic acid
    1,2,22,23
    1,2,22,23
    Sugar
    Sugar
    50 percent target mRNA inhibition
    25233814
    SM4247
    AACCUUACCCACCUCAUGUAUCU
    AGAUACAUGAGGUGGGUAAGGUU
    Serinol nucleic acid
    0
    1,2,3,4,5,6,7,8,9,10,11,12,13,14,15,16,17,18,19,20,21,22,23
    0
    Sugar
    0
    0 percent target mRNA inhibition
    25233814
    SM4248
    AACCUUACCCACCUCAUGUAUCU
    AGAUACAUGAGGUGGGUAAGGUU
    2-O-Methyl ribose
    0
    1,2,22,23
    0
    Sugar
    0
    96 percent target mRNA inhibition
    25233814
    SM4249
    AACCUUACCCACCUCAUGUAUCU
    AGAUACAUGAGGUGGGUAAGGUU
    0
    2-O-Methyl ribose
    0
    1,2,22,23
    0
    Sugar
    62 percent target mRNA inhibition
    25233814
    SM4251
    AACCUUACCCACCUCAUGUAUCU
    AGAUACAUGAGGUGGGUAAGGUU
    Serinol nucleic acid
    0
    1,2
    0
    Sugar
    0
    96 percent target mRNA inhibition
    25233814
    SM4252
    AACCUUACCCACCUCAUGUAUCU
    AGAUACAUGAGGUGGGUAAGGUU
    Serinol nucleic acid
    0
    22,23
    0
    Sugar
    0
    91 percent target mRNA inhibition
    25233814
    SM4253
    AACCUUACCCACCUCAUGUAUCU
    AGAUACAUGAGGUGGGUAAGGUU
    0
    Serinol nucleic acid
    0
    22,23
    0
    Sugar
    91 percent target mRNA inhibition
    25233814
    SM4254
    AACCUUACCCACCUCAUGUAUCU
    AGAUACAUGAGGUGGGUAAGGUU
    0
    Serinol nucleic acid
    0
    1,2
    0
    Sugar
    91 percent target mRNA inhibition
    25233814
    SM4255
    AACCUUACCCACCUCAUGUAUCU
    AGAUACAUGAGGUGGGUAAGGUU
    Serinol nucleic acid
    Serinol nucleic acid
    1,2
    22,23
    Sugar
    Sugar
    87 percent target mRNA inhibition
    25233814
    SM4256
    AACCUUACCCACCUCAUGUAUCU
    AGAUACAUGAGGUGGGUAAGGUU
    Serinol nucleic acid
    Serinol nucleic acid
    1,2
    1,2
    Sugar
    Sugar
    90 percent target mRNA inhibition
    25233814
    SM4257
    AACCUUACCCACCUCAUGUAUCU
    AGAUACAUGAGGUGGGUAAGGUU
    Serinol nucleic acid
    Serinol nucleic acid
    22,23
    22,23
    Sugar
    Sugar
    97 percent target mRNA inhibition
    25233814