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Note: (i) 0 indicates modification in opposite strand. (ii) Multiple modifications are separated bt asterisk (*).
  • By modification in sense strand

  • By modification position in sense strand

  • By modification in antisense strand

  • By modification position in antisense strand

  • Reference
    • Total number of Results for 25233814 are 64
    Results from 50 - 75
    SMDBidsiRNA (sense/antisense) 5'>3'Modification (sense/antisense)Position (sense/antisense) Modified component (sense/antisense) Efficacy (%)Reference
    SM4283
    AACCUUACCCACCUCAUGUAUCU
    AGAUACAUGAGGUGGGUAAGGUU
    Serinol nucleic acid
    0
    1,2,3,4,5,6,7,17,18,19,20,21,22,23
    0
    Sugar
    0
    0 percent target mRNA inhibition
    25233814
    SM4284
    AACCUUACCCACCUCAUGUAUCU
    AGAUACAUGAGGUGGGUAAGGUU
    Serinol nucleic acid
    Serinol nucleic acid
    1,23
    23
    Sugar
    Sugar
    20 percent target mRNA inhibition
    25233814
    SM4285
    AACCUUACCCACCUCAUGUAUCU
    AGAUACAUGAGGUGGGUAAGGUU
    Serinol nucleic acid
    Serinol nucleic acid
    1,2,22,23
    22,23
    Sugar
    Sugar
    0 percent target mRNA inhibition
    25233814
    SM4286
    AACCUUACCCACCUCAUGUAUCU
    AGAUACAUGAGGUGGGUAAGGUU
    Serinol nucleic acid
    Serinol nucleic acid
    1,2,3,21,22,23
    21,22,23
    Sugar
    Sugar
    0 percent target mRNA inhibition
    25233814
    SM4287
    AACCUUACCCACCUCAUGUAUCU
    AGAUACAUGAGGUGGGUAAGGUU
    Serinol nucleic acid
    Serinol nucleic acid
    1,2,3,4,5,19,20,21,22,23
    19,20,21,22,23
    Sugar
    Sugar
    0 percent target mRNA inhibition
    25233814
    SM4288
    AACCUUACCCACCUCAUGUAUCU
    AGAUACAUGAGGUGGGUAAGGUU
    Serinol nucleic acid
    Serinol nucleic acid
    1,2,3,4,5,6,7,17,18,19,20,21,22,23
    17,18,19,20,21,22,23
    Sugar
    Sugar
    8 percent target mRNA inhibition
    25233814
    SM4289
    AACCUUACCCACCUCAUGUAUCU
    AUACAUGAGGUGGGUAAGGUU
    Serinol nucleic acid
    0
    1,2,22,23
    0
    Sugar
    0
    78 percent target mRNA inhibition
    25233814
    SM4290
    AACCUUACCCACCUCAUGUAUCU
    AUACAUGAGGUGGGUAAGGUU
    Serinol nucleic acid
    Phosphate
    1,2,22,23
    1
    Sugar
    Sugar
    80 percent target mRNA inhibition
    25233814
    SM4291
    AACCUUACCCACCUCAUGUAUCU
    AUACAUGAGGUGGGUAAGGUU
    Serinol nucleic acid
    Serinol nucleic acid
    1,2,22,23
    20,21
    Sugar
    Sugar
    81 percent target mRNA inhibition
    25233814
    SM4292
    AACCUUACCCACCUCAUGUAUCU
    AUACAUGAGGUGGGUAAGGUU
    Serinol nucleic acid
    Phosphate* Serinol nucleic acid
    1,2,22,23
    1 * 20,21
    Sugar
    Sugar
    78 percent target mRNA inhibition
    25233814
    SM4293
    AACCUUACCCACCUCAUGUAUCU
    AUACAUGAGGUGGGUAAGGUU
    Serinol nucleic acid
    0
    1,2,22,23
    0
    Sugar
    0
    5 percent target mRNA inhibition
    25233814
    SM4294
    AACCUUACCCACCUCAUGUAUCU
    AUACAUGAGGUGGGUAAGGUU
    Serinol nucleic acid
    Phosphate
    1,2,22,23
    1
    Sugar
    Sugar
    5 percent target mRNA inhibition
    25233814
    SM4295
    AACCUUACCCACCUCAUGUAUCU
    AUACAUGAGGUGGGUAAGGUU
    Serinol nucleic acid
    Serinol nucleic acid
    1,2,22,23
    20,21
    Sugar
    Sugar
    0 percent target mRNA inhibition
    25233814
    SM4296
    AACCUUACCCACCUCAUGUAUCU
    AUACAUGAGGUGGGUAAGGUU
    Serinol nucleic acid
    Phosphate* Serinol nucleic acid
    1,2,22,23
    1 * 20,21
    Sugar
    Sugar
    0 percent target mRNA inhibition
    25233814