Browse By

Note: (i) 0 indicates modification in opposite strand. (ii) Multiple modifications are separated bt asterisk (*).

• By modification in sense strand


• By modification position in sense strand


• By modification in antisense strand


• By modification position in antisense strand


• Reference
Total number of Results for EP2548962A1 are 39
Results from 0 - 25

« previous12next »

SMDBid	siRNA (sense/antisense) 5'>3'	Modification (sense/antisense)	Position (sense/antisense)	Modified component (sense/antisense)	Efficacy (%)	Reference
SM4680	NNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNN	Locked nucleic acid Locked nucleic acid	1,20,21 0	Sugar Sugar	80 percent target mRNA inhibition	EP2548962A1
SM4681	NNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNN	Locked nucleic acid Locked nucleic acid	1,20,21 20,21	Sugar Sugar	70 percent target mRNA inhibition	EP2548962A1
SM4682	NNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNN	Locked nucleic acid Locked nucleic acid	1,2,13,14 9,10,19,20	Sugar Sugar	60 percent target mRNA inhibition	EP2548962A1
SM4683	NNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNN	Locked nucleic acid 0	1,2,13,14 0	Sugar 0	80 percent target mRNA inhibition	EP2548962A1
SM4684	NNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNN	Locked nucleic acid Locked nucleic acid	1,2,10,14 11,12,19,20	Sugar Sugar	10 percent target mRNA inhibition	EP2548962A1
SM4685	NNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNN	Locked nucleic acid 0	1,2,10,14 0	Sugar 0	69 percent target mRNA inhibition	EP2548962A1
SM4686	NNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNN	Locked nucleic acid Locked nucleic acid	1,2 2 * 1	Sugar Sugar	70 percent target mRNA inhibition	EP2548962A1
SM4687	NNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNN	Locked nucleic acid Locked nucleic acid	1,2 0	Sugar Sugar	72 percent target mRNA inhibition	EP2548962A1
SM4689	NNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNN	Locked nucleic acid 0	1,20,21 0	Sugar 0	0 percent target mRNA inhibition	EP2548962A1
SM4690	NNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNN	Locked nucleic acid Locked nucleic acid	1,20,21 20,21	Sugar Sugar	0 percent target mRNA inhibition	EP2548962A1
SM4691	NNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNN	Locked nucleic acid Locked nucleic acid	1,2,13,14 9,10,19,20	Sugar Sugar	0 percent target mRNA inhibition	EP2548962A1
SM4692	NNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNN	Locked nucleic acid 0	1,2,13,14 0	Sugar 0	0 percent target mRNA inhibition	EP2548962A1
SM4693	NNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNN	Locked nucleic acid Locked nucleic acid	1,2,10,14 11,12,19,20	Sugar Sugar	0 percent target mRNA inhibition	EP2548962A1
SM4694	NNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNN	Locked nucleic acid 0	1,2,10,14 0	Sugar 0	0 percent target mRNA inhibition	EP2548962A1
SM4695	NNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNN	Locked nucleic acid Locked nucleic acid	1,2 2 * 1	Sugar Sugar	0 percent target mRNA inhibition	EP2548962A1
SM4696	NNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNN	Locked nucleic acid 0	1,2 0	Sugar 0	0 percent target mRNA inhibition	EP2548962A1
SM4697	NNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNN	2-O-Methyl 0	1,2,12,13 0	Sugar 0	70 percent target mRNA inhibition	EP2548962A1
SM4698	NNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNN	2-O-Methyl 0	1,2,13,14 0	Sugar 0	75 percent target mRNA inhibition	EP2548962A1
SM4699	NNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNN	2-O-Methyl 0	1,2,14,15 0	Sugar 0	70 percent target mRNA inhibition	EP2548962A1
SM4700	NNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNN	2-O-Methyl 0	1,2,10,12 0	Sugar 0	70 percent target mRNA inhibition	EP2548962A1
SM4701	NNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNN	2-O-Methyl 0	1,2,10,14 0	Sugar 0	70 percent target mRNA inhibition	EP2548962A1
SM4702	NNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNN	2-O-Methyl 2-O-Methyl* Phosphate	1,2 2 * 1	Sugar Sugar	68 percent target mRNA inhibition	EP2548962A1
SM4703	NNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNN	2-O-Methyl 0	1,2,12,13 0	Sugar 0	0 percent target mRNA inhibition	EP2548962A1
SM4704	NNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNN	2-O-Methyl 0	1,2,13,14 0	Sugar 0	0 percent target mRNA inhibition	EP2548962A1
SM4705	NNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNN	2-O-Methyl 0	1,2,14,15 0	Sugar 0	0 percent target mRNA inhibition	EP2548962A1



« previous12next »