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Note: (i) 0 indicates modification in opposite strand. (ii) Multiple modifications are separated bt asterisk (*).

• By modification in sense strand


• By modification position in sense strand


• By modification in antisense strand


• By modification position in antisense strand


• Reference
Total number of Results for US 20080249039 A1 are 19
Results from 0 - 25


SMDBid	siRNA (sense/antisense) 5'>3'	Modification (sense/antisense)	Position (sense/antisense)	Modified component (sense/antisense)	Efficacy (%)	Reference
SM4660	CUUACGCUGAGUACUUCGATT UCGAAGUACUCAGCGUAAGTT	0 Locked nucleic acid* Thymidine	0 10 * 10	0 Sugar ; Base	95 percent target mRNA inhibition	US 20080249039 A1
SM4661	CUUACGCUGAGUACUUCGATT UCGAAGUACUCAGCGUAAGTT	0 Locked nucleic acid	0 2	0 Sugar	0 percent target mRNA inhibition	US 20080249039 A1
SM4662	CUUACGCUGAGUACUUCGATT UCGAAGUACUCAGCGUAAGTT	0 Locked nucleic acid	0 3	0 Sugar	82 percent target mRNA inhibition	US 20080249039 A1
SM4663	CUUACGCUGAGUACUUCGATT UCGAAGUACUCAGCGUAAGTT	0 Locked nucleic acid	0 4	0 Sugar	85 percent target mRNA inhibition	US 20080249039 A1
SM4664	CUUACGCUGAGUACUUCGATT UCGAAGUACUCAGCGUAAGTT	0 Locked nucleic acid	0 5	0 Sugar	83 percent target mRNA inhibition	US 20080249039 A1
SM4665	CUUACGCUGAGUACUUCGATT UCGAAGUACUCAGCGUAAGTT	0 Locked nucleic acid	0 6	0 Sugar	82 percent target mRNA inhibition	US 20080249039 A1
SM4666	CUUACGCUGAGUACUUCGATT UCGAAGUACUCAGCGUAAGTT	0 Locked nucleic acid	0 7	0 Sugar	81 percent target mRNA inhibition	US 20080249039 A1
SM4667	CUUACGCUGAGUACUUCGATT UCGAAGUACUCAGCGUAAGTT	0 Locked nucleic acid	0 8	0 Sugar	86 percent target mRNA inhibition	US 20080249039 A1
SM4668	CUUACGCUGAGUACUUCGATT UCGAAGUACUCAGCGUAAGTT	0 Locked nucleic acid	0 9	0 Sugar	85 percent target mRNA inhibition	US 20080249039 A1
SM4669	CUUACGCUGAGUACUUCGATT UCGAAGUACUCAGCGUAAGTT	0 Locked nucleic acid* Thymidine	0 10 * 10	0 Sugar ; Base	91 percent target mRNA inhibition	US 20080249039 A1
SM4670	CUUACGCUGAGUACUUCGATT UCGAAGUACUCAGCGUAAGTT	0 Locked nucleic acid	0 11	0 Sugar	50 percent target mRNA inhibition	US 20080249039 A1
SM4671	CUUACGCUGAGUACUUCGATT UCGAAGUACUCAGCGUAAGTT	0 Locked nucleic acid	0 12	0 Sugar	89 percent target mRNA inhibition	US 20080249039 A1
SM4672	CUUACGCUGAGUACUUCGATT UCGAAGUACUCAGCGUAAGTT	0 Locked nucleic acid	0 13	0 Sugar	65 percent target mRNA inhibition	US 20080249039 A1
SM4673	CUUACGCUGAGUACUUCGATT UCGAAGUACUCAGCGUAAGTT	0 Locked nucleic acid	0 14	0 Sugar	43 percent target mRNA inhibition	US 20080249039 A1
SM4674	CUUACGCUGAGUACUUCGATT UCGAAGUACUCAGCGUAAGTT	0 Locked nucleic acid	0 15	0 Sugar	85 percent target mRNA inhibition	US 20080249039 A1
SM4675	CUUACGCUGAGUACUUCGATT UCGAAGUACUCAGCGUAAGTT	0 Locked nucleic acid	0 16	0 Sugar	81 percent target mRNA inhibition	US 20080249039 A1
SM4676	CUUACGCUGAGUACUUCGATT UCGAAGUACUCAGCGUAAGTT	0 Locked nucleic acid	0 17	0 Sugar	93 percent target mRNA inhibition	US 20080249039 A1
SM4677	CUUACGCUGAGUACUUCGATT UCGAAGUACUCAGCGUAAGTT	0 Locked nucleic acid	0 18	0 Sugar	92 percent target mRNA inhibition	US 20080249039 A1
SM4678	CUUACGCUGAGUACUUCGATT UCGAAGUACUCAGCGUAAGTT	0 Locked nucleic acid	0 19	0 Sugar	88 percent target mRNA inhibition	US 20080249039 A1