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Note: (i) 0 indicates modification in opposite strand. (ii) Multiple modifications are separated bt asterisk (*).
  • By modification in sense strand

  • By modification position in sense strand

  • By modification in antisense strand

  • By modification position in antisense strand

  • Reference
    • Total number of Results for 2-Thiouridine are 9
    Results from 0 - 25
    SMDBidsiRNA (sense/antisense) 5'>3'Modification (sense/antisense)Position (sense/antisense) Modified component (sense/antisense) Efficacy (%)Reference
    SM2304
    ACAUGAAGCAGCACGACUUTT
    AAGUCGUGCUGCUUCAUGUTT
    0
    2-Thiouridine
    0
    19
    0
    Base
    91 percent target mRNA inhibition
    17585051
    SM2307
    ACAUGAAGCAGCACGACUUTT
    AAGUCGUGCUGCUUCAUGUTT
    0
    2-Thiouridine
    0
    10
    0
    Base
    86 percent target mRNA inhibition
    17585051
    SM2311
    ACAUGAAGCAGCACGACUUTT
    AAGUCGUGCUGCUUCAUGUTT
    Dihydrouridine
    2-Thiouridine
    19
    19
    Base
    Base
    92 percent target mRNA inhibition
    17585051
    SM2313
    ACAUGAAGCAGCACGACUUTT
    AAGUCGUGCUGCUUCAUGUTT
    Dihydrouridine
    2-Thiouridine
    19
    10
    Base
    Base
    87 percent target mRNA inhibition
    17585051
    SM2317
    ACAUGAAGCAGCACGACUUTT
    AAGUCGUGCUGCUUCAUGUTT
    0
    2-Thiouridine
    0
    4,7,10,13,14,17,19
    0
    Base
    89 percent target mRNA inhibition
    17585051
    SM2318
    AUGAAGCAGCACGACUUTT
    AAGUCGUGCUGCUUCAUGUTT
    0
    2-Thiouridine
    0
    4,7,10,13,17,19
    0
    Base
    88 percent target mRNA inhibition
    17585051
    SM2319
    GAAGCAGCACGACUUTT
    AAGUCGUGCUGCUUCAUGUTT
    0
    2-Thiouridine
    0
    4,7,10,13,14
    0
    Base
    20 percent target mRNA inhibition
    17585051
    SM2324
    AUACAGGCAGCAGUAACUUUTT
    AAAGUUACUGCUGCCUGUAUTT
    0
    2-Thiouridine
    0
    20
    0
    Base
    72 percent target mRNA inhibition
    17585051
    SM2326
    AUACAGGCAGCAGUAACUUUTT
    AAAGUUACUGCUGCCUGUAUTT
    0
    2-Thiouridine
    0
    18, 20
    0
    Base
    76 percent target mRNA inhibition
    17585051