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Note: (i) 0 indicates modification in opposite strand. (ii) Multiple modifications are separated bt asterisk (*).

• By modification in sense strand


• By modification position in sense strand


• By modification in antisense strand


• By modification position in antisense strand


• Reference
Total number of Results for 2-O-Methyl-4-Thioribose* 2-Deoxy are 7
Results from 0 - 25


SMDBid	siRNA (sense/antisense) 5'>3'	Modification (sense/antisense)	Position (sense/antisense)	Modified component (sense/antisense)	Efficacy (%)	Reference
SM2164	GCGCUGCUGGUGCCAACCCTT GGGUUGGCACCAGCAGCGCTT	2-O-Methyl-4-Thioribose* 2-Deoxy 2-O-Methyl-4-Thioribose* 2-Deoxy	1,2,3,4,16,17,18,19 * 20,21 16,17,18,19 * 20,21	Sugar Sugar	48 percent target mRNA inhibition	22411910
SM2165	GCGCUGCUGGUGCCAACCCTT GGGUUGGCACCAGCAGCGCTT	2-O-Methyl-4-Thioribose* 2-Deoxy 2-O-Methyl-4-Thioribose* 2-Deoxy	1,2,3,4,16,17,18,19 * 20,21 1,2,18,19 * 20,21	Sugar Sugar	48 percent target mRNA inhibition	22411910
SM2166	GCGCUGCUGGUGCCAACCCTT GGGUUGGCACCAGCAGCGCTT	2-O-Methyl-4-Thioribose* 2-Deoxy 2-Deoxy	1,2,3,4,16,17,18,19 * 20,21 20,21	Sugar Sugar	60 percent target mRNA inhibition	22411910
SM2167	GCGCUGCUGGUGCCAACCCTT GGGUUGGCACCAGCAGCGCTT	2-O-Methyl-4-Thioribose* 2-Deoxy 2-Deoxy	1,2,3,4,18,19 * 20,21 20,21	Sugar Sugar	66 percent target mRNA inhibition	22411910
SM2168	GCGCUGCUGGUGCCAACCCTT GGGUUGGCACCAGCAGCGCTT	2-O-Methyl-4-Thioribose* 2-Deoxy 2-Deoxy	1,2,3,4 * 20,21 20,21	Sugar Sugar	64 percent target mRNA inhibition	22411910
SM2169	GCGCUGCUGGUGCCAACCCTT GGGUUGGCACCAGCAGCGCTT	2-O-Methyl-4-Thioribose* 2-Deoxy 2-Deoxy	1,2,3,17,18,19 * 20,21 20,21	Sugar Sugar	80 percent target mRNA inhibition	22411910
SM2170	GCGCUGCUGGUGCCAACCCTT GGGUUGGCACCAGCAGCGCTT	2-O-Methyl-4-Thioribose* 2-Deoxy 2-Deoxy	1,2,3,17,18,19 * 20,21 20,21	Sugar Sugar	IC-50 = 26.3 nM for target mRNA	22411910