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Note: (i) 0 indicates modification in opposite strand. (ii) Multiple modifications are separated bt asterisk (*).
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  • By modification in antisense strand

  • By modification position in antisense strand

  • Reference
    • Total number of Results for Assymetric siRNA (3-End Overhang) are 6
    Results from 0 - 25
    SMDBidsiRNA (sense/antisense) 5'>3'Modification (sense/antisense)Position (sense/antisense) Modified component (sense/antisense) Efficacy (%)Reference
    SM2465
    CGGAGGCUGGGAUGCCUUUTT
    AAAGGCAUCCCAGCCUCCGTT
    Assymetric siRNA (3-End Overhang)
    Assymetric siRNA (3-End Overhang)
    21
    1
    NA
    NA
    60 percent target mRNA inhibition
    23135004
    SM2466
    GAGGCUGGGAUGCCUUUTT
    AAAGGCAUCCCAGCCUCCGTT
    Assymetric siRNA (3-End Overhang)
    Assymetric siRNA (3-End Overhang)
    19
    1
    NA
    NA
    74 percent target mRNA inhibition
    23135004
    SM2467
    AGGCUGGGAUGCCUUUTT
    AAAGGCAUCCCAGCCUCCGTT
    Assymetric siRNA (3-End Overhang)
    Assymetric siRNA (3-End Overhang)
    18
    1
    NA
    NA
    18 percent target mRNA inhibition
    23135004
    SM2468
    GGCUGGGAUGCCUUUTT
    AAAGGCAUCCCAGCCUCCGTT
    Assymetric siRNA (3-End Overhang)
    Assymetric siRNA (3-End Overhang)
    17
    1
    NA
    NA
    16 percent target mRNA inhibition
    23135004
    SM2469
    GCUGGGAUGCCUUUTT
    AAAGGCAUCCCAGCCUCCGTT
    Assymetric siRNA (3-End Overhang)
    Assymetric siRNA (3-End Overhang)
    16
    1
    NA
    NA
    10 percent target mRNA inhibition
    23135004
    SM2470
    CUGGGAUGCCUUUTT
    AAAGGCAUCCCAGCCUCCGTT
    Assymetric siRNA (3-End Overhang)
    Assymetric siRNA (3-End Overhang)
    15
    1
    NA
    NA
    14 percent target mRNA inhibition
    23135004