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Note: (i) 0 indicates modification in opposite strand. (ii) Multiple modifications are separated bt asterisk (*).
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  • By modification position in antisense strand

  • Reference
    • Total number of Results for Phosphorothioate* Dimethoxy-Nitrophenyl Ethyl group are 4
    Results from 0 - 25
    SMDBidsiRNA (sense/antisense) 5'>3'Modification (sense/antisense)Position (sense/antisense) Modified component (sense/antisense) Efficacy (%)Reference
    SM2944
    AAGCUGACCCUGAAGUUCAUCUGCACC
    GGUGCAGAUGAACUUCAGGGUCAGCUU
    Phosphorothioate* Dimethoxy-Nitrophenyl Ethyl group
    Phosphorothioate* Dimethoxy-Nitrophenyl Ethyl group
    2,27 * 1,27
    2,27 * 1,27
    Phosphate
    Phosphate
    27 percent target mRNA inhibition
    21739319
    SM2945
    AAGCUGACCCUGAAGUUCAUCUGCACC
    GGUGCAGAUGAACUUCAGGGUCAGCUU
    Phosphorothioate* Dimethoxy-Nitrophenyl Ethyl group
    Phosphorothioate* Dimethoxy-Nitrophenyl Ethyl group
    2,3,4,25,26,27 * 1,27
    2,3,4,25,26,27 * 1,27
    Phosphate
    Phosphate
    40 percent target mRNA inhibition
    21739319
    SM2950
    AAGCUGACCCUGAAGUUCAUCUGCACC
    GGUGCAGAUGAACUUCAGGGUCAGCUU
    Phosphorothioate* Dimethoxy-Nitrophenyl Ethyl group
    Phosphorothioate* Dimethoxy-Nitrophenyl Ethyl group
    2,27 * 1,27
    2,27 * 1,27
    Phosphate
    Phosphate
    89 percent target mRNA inhibition
    21739319
    SM2951
    AAGCUGACCCUGAAGUUCAUCUGCACC
    GGUGCAGAUGAACUUCAGGGUCAGCUU
    Phosphorothioate* Dimethoxy-Nitrophenyl Ethyl group
    Phosphorothioate* Dimethoxy-Nitrophenyl Ethyl group
    2,3,4,25,26,27 * 1,27
    2,3,4,25,26,27 * 1,27
    Phosphate
    Phosphate
    88 percent target mRNA inhibition
    21739319