VIRsiRNAdb

Browse BY

• Family of Virus


• Virus Name


• Gene Name


• Pubmed Id


• VsiRNAid

Total number of Results for NS1 are 13
Results from 0 - 25

siRNA sequence "ggcagcaauucauugaguaug" alignment with "Human Respiratory Syncytial Virus [HRSV]" virus reference Genome sequences
siRNA sequence matching with "ggcagcaauucauugaguaug" Human Respiratory Syncytial Virus [HRSV]" Virus reference Genome sequences
Browse all the records for "Human Respiratory Syncytial Virus [HRSV]" virus
Browse "virsi2022 " record
Length: 21
GC Content:43 %
GenBank Acc: AF035006

Offtargets for "ggcagcaauucauugaguaug" siRNA in Human Genome sequences
See AF035006 at Genbank
Pubmed:17270047
Article:Respiratory syncytial virus infection in Fischer 344 rats is attenuated by short interfering RNA against the RSV-NS1 gene.
Authors:Kong X, Zhang W, Lockey RF, Auais A, Piedimonte G, Mohapatra SS.
Journal:Genet Vaccines Ther. 2007 Feb 1;5:4.
Entrez:17270047

siRNA sequence "ggcagcaauucauugaguaug" alignment with "Human Respiratory Syncytial Virus [HRSV]" virus reference Genome sequences
siRNA sequence matching with "ggcagcaauucauugaguaug" Human Respiratory Syncytial Virus [HRSV]" Virus reference Genome sequences
Browse all the records for "Human Respiratory Syncytial Virus [HRSV]" virus
Browse "virsi2023 " record
Length: 21
GC Content:43 %
GenBank Acc: AF035006

Offtargets for "ggcagcaauucauugaguaug" siRNA in Human Genome sequences
See AF035006 at Genbank
Pubmed:17270047
Article:Respiratory syncytial virus infection in Fischer 344 rats is attenuated by short interfering RNA against the RSV-NS1 gene.
Authors:Kong X, Zhang W, Lockey RF, Auais A, Piedimonte G, Mohapatra SS.
Journal:Genet Vaccines Ther. 2007 Feb 1;5:4.
Entrez:17270047

siRNA sequence "gggcaguucugggugaagu" alignment with "West Nile Virus [WNV]" virus reference Genome sequences
siRNA sequence matching with "gggcaguucugggugaagu" West Nile Virus [WNV]" Virus reference Genome sequences
Browse all the records for "West Nile Virus [WNV]" virus
Browse "virsi1098 " record
Length: 19
GC Content:58 %
Starting position: 3110
Strain of Virus: Linage
GenBank Acc: DQ211652
Transfection Reagent: Lipid-Based Reagent/Electroporation
Incubation Time (Hours):48

Offtargets for "gggcaguucugggugaagu" siRNA in Human Genome sequences
See DQ211652 at Genbank
Pubmed:15985182
Article:Actively replicating West Nile virus is resistant to cytoplasmic delivery of siRNA.
Authors:Geiss BJ, Pierson TC, Diamond MS.
Journal:Virol J. 2005 Jun 28;2:53.
Entrez:15985182

siRNA sequence "cuacggucacccugaguga" alignment with "West Nile Virus [WNV]" virus reference Genome sequences
siRNA sequence matching with "cuacggucacccugaguga" West Nile Virus [WNV]" Virus reference Genome sequences
Browse all the records for "West Nile Virus [WNV]" virus
Browse "virsi1099 " record
Length: 19
GC Content:58 %
Starting position: 3317
Strain of Virus: Linage
GenBank Acc: DQ211652
Transfection Reagent: Lipid-Based Reagent/Electroporation
Incubation Time (Hours):48

Offtargets for "cuacggucacccugaguga" siRNA in Human Genome sequences
See DQ211652 at Genbank
Pubmed:15985182
Article:Actively replicating West Nile virus is resistant to cytoplasmic delivery of siRNA.
Authors:Geiss BJ, Pierson TC, Diamond MS.
Journal:Virol J. 2005 Jun 28;2:53.
Entrez:15985182

siRNA sequence "gugauucaacaaugaccaa" alignment with "Human Respiratory Syncytial Virus [HRSV]" virus reference Genome sequences
siRNA sequence matching with "gugauucaacaaugaccaa" Human Respiratory Syncytial Virus [HRSV]" Virus reference Genome sequences
Browse all the records for "Human Respiratory Syncytial Virus [HRSV]" virus
Browse "virsi2171 " record
Length: 19
GC Content:37 %
GenBank Acc: U35029
Transfection Reagent: TransIT-TKO
Incubation Time (Hours):60

Offtargets for "gugauucaacaaugaccaa" siRNA in Human Genome sequences
See U35029 at Genbank
Pubmed:17151097
Article:Nonstructural proteins of respiratory syncytial virus suppress premature apoptosis by an NF-kappaB-dependent, interferon-independent mechanism and facilitate virus growth.
Authors:Bitko V, Shulyayeva O, Mazumder B, Musiyenko A, Ramaswamy M, Look DC, Barik S.
Journal:J Virol. 2007 Feb;81(4):1786-95. Epub 2006 Dec 6.
Entrez:17151097

siRNA sequence "gcaauucauugaguaugcu" alignment with "Human Respiratory Syncytial Virus [HRSV]" virus reference Genome sequences
siRNA sequence matching with "gcaauucauugaguaugcu" Human Respiratory Syncytial Virus [HRSV]" Virus reference Genome sequences
Browse all the records for "Human Respiratory Syncytial Virus [HRSV]" virus
Browse "virsi2020 " record
Length: 19
GC Content:37 %
GenBank Acc: M74568

Offtargets for "gcaauucauugaguaugcu" siRNA in Human Genome sequences
See M74568 at Genbank
Pubmed:15619625
Article:Inhibition of respiratory syncytial virus infection with intranasal siRNA nanoparticles targeting the viral NS1 gene.
Authors:Zhang W, Yang H, Kong X, Mohapatra S, San Juan-Vergara H, Hellermann G, Behera S, Singam R, Lockey RF, Mohapatra SS.
Journal:Nat Med. 2005 Jan;11(1):56-62. Epub 2004 Dec 26. Erratum in: Nat Med. 2005 Feb;11(2):233.
Entrez:15619625

siRNA sequence "ugcccguuuucaaaccggg" alignment with "Yellow Fever Virus" virus reference Genome sequences
siRNA sequence matching with "ugcccguuuucaaaccggg" Yellow Fever Virus" Virus reference Genome sequences
Browse all the records for "Yellow Fever Virus" virus
Browse "virsi2308 " record
Length: 19
GC Content:58 %
Strain of Virus: 17DD
GenBank Acc: NC_002031
Transfection Reagent: Lipofectamine 2000

Offtargets for "ugcccguuuucaaaccggg" siRNA in Human Genome sequences
See NC_002031 at Genbank
Pubmed:19169857
Article:RNA interference inhibits yellow fever virus replication in vitro and in vivo.
Authors:Pacca CC, Severino AA, Mondini A, Rahal P, D'avila SG, Cordeiro JA, Nogueira MC, Bronzoni RV, Nogueira ML.
Journal:Virus Genes. 2009 Apr;38(2):224-31. Epub 2009 Jan 25.
Entrez:19169857

siRNA sequence "gacuucggcuuuggcauca" alignment with "Japanese Encephalitis Virus [JE]" virus reference Genome sequences
siRNA sequence matching with "gacuucggcuuuggcauca" Japanese Encephalitis Virus [JE]" Virus reference Genome sequences
Browse all the records for "Japanese Encephalitis Virus [JE]" virus
Browse "virsi1485 " record
Length: 19
GC Content:53 %
Starting position: 451
Strain of Virus: SA14-14-2
GenBank Acc: AF315119
Transfection Reagent: Lipofectamine
Incubation Time (Hours):48

Offtargets for "gacuucggcuuuggcauca" siRNA in Human Genome sequences
See AF315119 at Genbank
Pubmed:16791421
Article:Inhibition of Japanese encephalitis virus NS1 protein expression in cell by small interfering RNAs.
Authors:Liu X, Cao S, Zhou R, Xu G, Xiao S, Yang Y, Sun M, Li Y, Chen H.
Journal:Virus Genes. 2006 Aug;33(1):69-75.
Entrez:16791421

siRNA sequence "cagcaugcaaaucgaagac" alignment with "Japanese Encephalitis Virus [JE]" virus reference Genome sequences
siRNA sequence matching with "cagcaugcaaaucgaagac" Japanese Encephalitis Virus [JE]" Virus reference Genome sequences
Browse all the records for "Japanese Encephalitis Virus [JE]" virus
Browse "virsi1484 " record
Length: 19
GC Content:47 %
Starting position: 451
Strain of Virus: SA14-14-2
GenBank Acc: AF315119
Transfection Reagent: Lipofectamine
Incubation Time (Hours):48

Offtargets for "cagcaugcaaaucgaagac" siRNA in Human Genome sequences
See AF315119 at Genbank
Pubmed:16791421
Article:Inhibition of Japanese encephalitis virus NS1 protein expression in cell by small interfering RNAs.
Authors:Liu X, Cao S, Zhou R, Xu G, Xiao S, Yang Y, Sun M, Li Y, Chen H.
Journal:Virus Genes. 2006 Aug;33(1):69-75.
Entrez:16791421

siRNA sequence "acgccuauccaugacgcaa" alignment with "Japanese Encephalitis Virus [JE]" virus reference Genome sequences
siRNA sequence matching with "acgccuauccaugacgcaa" Japanese Encephalitis Virus [JE]" Virus reference Genome sequences
Browse all the records for "Japanese Encephalitis Virus [JE]" virus
Browse "virsi1483 " record
Length: 19
GC Content:53 %
Starting position: 304
Strain of Virus: SA14-14-2
GenBank Acc: AF315119
Transfection Reagent: Lipofectamine
Incubation Time (Hours):48

Offtargets for "acgccuauccaugacgcaa" siRNA in Human Genome sequences
See AF315119 at Genbank
Pubmed:16791421
Article:Inhibition of Japanese encephalitis virus NS1 protein expression in cell by small interfering RNAs.
Authors:Liu X, Cao S, Zhou R, Xu G, Xiao S, Yang Y, Sun M, Li Y, Chen H.
Journal:Virus Genes. 2006 Aug;33(1):69-75.
Entrez:16791421

siRNA sequence "agcgcacaaggaaggcgug" alignment with "Japanese Encephalitis Virus [JE]" virus reference Genome sequences
siRNA sequence matching with "agcgcacaaggaaggcgug" Japanese Encephalitis Virus [JE]" Virus reference Genome sequences
Browse all the records for "Japanese Encephalitis Virus [JE]" virus
Browse "virsi1407 " record
Length: 19
GC Content:63 %
Starting position: 142
Strain of Virus: SA14-14-2
GenBank Acc: AF315119
Transfection Reagent: Lipofectamine
Incubation Time (Hours):48

Offtargets for "agcgcacaaggaaggcgug" siRNA in Human Genome sequences
See AF315119 at Genbank
Pubmed:16791421
Article:Inhibition of Japanese encephalitis virus NS1 protein expression in cell by small interfering RNAs.
Authors:Liu X, Cao S, Zhou R, Xu G, Xiao S, Yang Y, Sun M, Li Y, Chen H.
Journal:Virus Genes. 2006 Aug;33(1):69-75.
Entrez:16791421

siRNA sequence "aauguccuggaucacacag" alignment with "West Nile Virus [WNV]" virus reference Genome sequences
siRNA sequence matching with "aauguccuggaucacacag" West Nile Virus [WNV]" Virus reference Genome sequences
Browse all the records for "West Nile Virus [WNV]" virus
Browse "virsi1247 " record
Length: 19
GC Content:47 %
Starting position: 2323
Strain of Virus: B956
GenBank Acc: AY532665
Transfection Reagent: Lipofectamine 2000
Incubation Time (Hours):72

Offtargets for "aauguccuggaucacacag" siRNA in Human Genome sequences
See AY532665 at Genbank
Pubmed:21423625
Article:Silencing early viral replication in macrophages and dendritic cells effectively suppresses flavivirus encephalitis.
Authors:Ye C, Abraham S, Wu H, Shankar P, Manjunath N.
Journal:PLoS One. 2011 Mar 15;6(3):e17889.
Entrez:21423625

siRNA sequence "gaacggcugucaagaacaa" alignment with "West Nile Virus [WNV]" virus reference Genome sequences
siRNA sequence matching with "gaacggcugucaagaacaa" West Nile Virus [WNV]" Virus reference Genome sequences
Browse all the records for "West Nile Virus [WNV]" virus
Browse "virsi2202 " record
Length: 19
GC Content:47 %
Strain of Virus: Isolate 2741
GenBank Acc: AF206518
Incubation Time (Hours):24

Offtargets for "gaacggcugucaagaacaa" siRNA in Human Genome sequences
See AF206518 at Genbank
Pubmed:19135091
Article:Effective siRNA targeting of the 3' untranslated region of the West Nile virus genome.
Authors:Anthony KG, Bai F, Krishnan MN, Fikrig E, Koski RA.
Journal:Antiviral Res. 2009 Jun;82(3):166-8. Epub 2009 Jan 7.
Entrez:19135091


VIRsiRNAid	siRNA Sequence	Virus_Name	Target Region	Cell Line	Test Object	Efficacy	PMID	Offtarget	Align With	ALIGN0 Result
virsi2022	ggcagcaauucauugaguaug	Human Respiratory Syncytial Virus [HRSV]	NS1	Rat Lung	Protein	Medium	17270047	Blast SL	refseqs
virsi2023	ggcagcaauucauugaguaug	Human Respiratory Syncytial Virus [HRSV]	NS1	Rat Lung	Protein	Medium	17270047	Blast SL	refseqs
virsi1098	gggcaguucugggugaagu	West Nile Virus [WNV]	NS1	Huh-7 .5	Protein	Low	15985182	Blast SL	refseqs
virsi1099	cuacggucacccugaguga	West Nile Virus [WNV]	NS1	Huh-7 .5	Protein	Low	15985182	Blast SL	refseqs
virsi2171	gugauucaacaaugaccaa	Human Respiratory Syncytial Virus [HRSV]	NS1	A549	mRNA	High	17151097	Blast SL	refseqs
virsi2020	gcaauucauugaguaugcu	Human Respiratory Syncytial Virus [HRSV]	NS1	A549	Protein	High	15619625	Blast SL	refseqs
virsi2308	ugcccguuuucaaaccggg	Yellow Fever Virus	NS1	Vero E6	Plaque Count	97	19169857	Blast SL	refseqs
virsi1485	gacuucggcuuuggcauca	Japanese Encephalitis Virus [JE]	NS1	Monkey Kidney Cells	Protein	90	16791421	Blast SL	refseqs
virsi1484	cagcaugcaaaucgaagac	Japanese Encephalitis Virus [JE]	NS1	Monkey Kidney Cells	Protein	85	16791421	Blast SL	refseqs
virsi1483	acgccuauccaugacgcaa	Japanese Encephalitis Virus [JE]	NS1	Monkey Kidney Cells	Protein	84	16791421	Blast SL	refseqs
virsi1407	agcgcacaaggaaggcgug	Japanese Encephalitis Virus [JE]	NS1	Monkey Kidney Cells	Protein	60	16791421	Blast SL	refseqs
virsi1247	aauguccuggaucacacag	West Nile Virus [WNV]	NS1	BHK-21	Cell Count	50	21423625	Blast SL	refseqs
virsi2202	gaacggcugucaagaacaa	West Nile Virus [WNV]	NS1	Vero	mRNA	30	19135091	Blast SL	refseqs



: siRNA specific for both strands
: siRNA specific for only one strands
: siRNA Not specific
SL: siRNA seedlocator algorithm