Browse By

Note: (i) 0 indicates modification in opposite strand. (ii) Multiple modifications are separated bt asterisk (*).
  • By modification in sense strand

  • By modification position in sense strand

  • By modification in antisense strand

  • By modification position in antisense strand

  • Reference
    • Total number of Results for 17539595 are 11
    Results from 0 - 25
    SMDBidsiRNA (sense/antisense) 5'>3'Modification (sense/antisense)Position (sense/antisense) Modified component (sense/antisense) Efficacy (%)Reference
    SM2332
    CUGGUAAAGCAUUCAGUAUTT
    AUACUGAAUGCUUUACCAGTT
    2-Deoxythymidine
    2-Deoxythymidine
    20,21
    20,21
    Sugar
    Sugar
    82 percent target mRNA inhibition
    17539595
    SM2333
    CUGGUAAAGCAUUCAGUATT
    AUACUGAAUGCUUUACCAGTT
    Aminoisonucleotide-thymidine* 2-Deoxythymidine
    2-Deoxythymidine
    19* 20,21
    20,21
    Base
    Sugar
    85 percent target mRNA inhibition
    17539595
    SM2334
    CTGGUAAAGCAUUCAGUATTT
    AUACUGAAUGCUUUACCAGTT
    Aminoisonucleotide-thymidine* 2-Deoxythymidine
    2-Deoxythymidine
    2* 20,21
    20,21
    Base
    Sugar
    83 percent target mRNA inhibition
    17539595
    SM2335
    CUGGUAAAGCAUUCAGUAUTT
    AUACUGAAUGCUUUACCAGTT
    Aminoisonucleotide-Adenine* 2-Deoxythymidine
    2-Deoxythymidine
    8* 20,21
    20,21
    Base
    Sugar
    78 percent target mRNA inhibition
    17539595
    SM2336
    CTGGUAAAGCAUUCAGUAUTT
    AUACUGAAUGCUUUACCAGTT
    Aminoisonucleotide-thymidine* 2-Deoxythymidine
    2-Deoxythymidine
    2,20* 21
    20,21
    Base
    Sugar
    62 percent target mRNA inhibition
    17539595
    SM2337
    CTGGUAAAGCAUUCAGUATT
    AUACUGAAUGCUUUACCAGTT
    Aminoisonucleotide-thymidine* Aminoisonucleotide-Adenine* 2-Deoxythymidine
    2-Deoxythymidine
    2,20* 6,15* 21
    20,21
    Base
    Sugar
    39 percent target mRNA inhibition
    17539595
    SM2338
    CUGGUAAAGCAUUCAGUAUTT
    AUACUGAAUGCUUUACCAGTT
    2-Deoxythymidine
    Aminoisonucleotide-Adenine* 2-Deoxythymidine
    20,21
    1* 20,21
    Sugar
    Base; Sugar
    39 percent target mRNA inhibition
    17539595
    SM2339
    CUGGUAAAGCAUUCAGUAUTT
    AUACUGAAUGCUUUACCAGTT
    2-Deoxythymidine
    Aminoisonucleotide-Adenine* 2-Deoxythymidine
    20,21
    18* 20,21
    Sugar
    Base; Sugar
    50 percent target mRNA inhibition
    17539595
    SM2340
    CUGGUAAAGCAUUCAGUAUTT
    AUACUGAAUGCUUUACCAGTT
    2-Deoxythymidine
    Aminoisonucleotide-Adenine* 2-Deoxythymidine
    20,21
    8* 20,21
    Sugar
    Base; Sugar
    2 percent target mRNA inhibition
    17539595
    SM2341
    CUGGUAAAGCAUUCAGUAUTT
    AUACUGAAUGCUUUACCAGTT
    2-Deoxythymidine
    Aminoisonucleotide-thymidine* Aminoisonucleotide-adenine* 2-Deoxythymidine
    20,21
    1* 20* 21
    Sugar
    Base; Sugar
    13 percent target mRNA inhibition
    17539595
    SM2342
    CUGGUAAAGCAUUCAGUAUTT
    AUACUGAAUGCUUUACCAGTT
    2-Deoxythymidine
    Aminoisonucleotide-thymidine* Aminoisonucleotide-adenine* 2-Deoxythymidine
    20,21
    1,20* 8,15 * 21
    Sugar
    Base; Sugar
    0 percent target mRNA inhibition
    17539595