SMDBid | siRNA (sense/antisense) 5'>3' | Modification (sense/antisense) | Position (sense/antisense) |
Modified component (sense/antisense) |
Efficacy (%) | Reference |
SM2207 |
GGCCUUUCACUACUCCUACGA GUAGGAGUAGUGAAAGGCCAG |
5-Amino 0 |
1 0 |
Sugar 0 |
79 percent target mRNA inhibition | 17894530 |
SM2209 |
CUGGCCUUUCACUACUCCUACGAGCAC GUGCUCGUAGGAGUAGUGAAAGGCCAG |
5-Amino 5-Amino |
1 1 |
Sugar Sugar |
83 percent target mRNA inhibition | 17894530 |
SM2210 |
CUGGCCUUUCACUACUCCUACGAGCAC GUGCUCGUAGGAGUAGUGAAAGGCCAG |
0 3-Amino |
0 27 |
0 Sugar |
76 percent target mRNA inhibition | 17894530 |
SM2211 |
CUGGCCUUUCACUACUCCUACGAGCAC GUGCUCGUAGGAGUAGUGAAAGGCCAG |
5-Amino 0 |
1 0 |
Sugar 0 |
97 percent target mRNA inhibition | 17894530 |
SM2212 |
CUGGCCUUUCACUACUCCUACGAGCAC GUGCUCGUAGGAGUAGUGAAAGGCCAG |
3-Amino 3-Amino |
27 27 |
Sugar Sugar |
58 percent target mRNA inhibition | 17894530 |
SM2213 |
CUGGCCUUUCACUACUCCUACGAGCAC GUGCUCGUAGGAGUAGUGAAAGGCCAG |
0 3-Amino |
0 27 |
0 Sugar |
84 percent target mRNA inhibition | 17894530 |
SM2214 |
CUGGCCUUUCACUACUCCUACGAGCAC GUGCUCGUAGGAGUAGUGAAAGGCCAG |
3-Amino 0 |
27 0 |
Sugar 0 |
79 percent target mRNA inhibition | 17894530 |
SM2215 |
CUGGCCUUUCACUACUCCUACGAGCAC GUGCUCGUAGGAGUAGUGAAAGGCCAG |
5-Amino 3-Amino |
1 27 |
Sugar Sugar |
89 percent target mRNA inhibition | 17894530 |
SM2216 |
CUGGCCUUUCACUACUCCUACGAGCAC GUGCUCGUAGGAGUAGUGAAAGGCCAG |
3-Amino 5-Amino |
27 1 |
Sugar Sugar |
67 percent target mRNA inhibition | 17894530 |
SM2218 |
CUGGCCUUUCACUACUCCUACGAGCAC GUGCUCGUAGGAGUAGUGAAAGGCCAG |
5-Amino 5-Amino |
1 27 |
Sugar Sugar |
51 percent target mRNA inhibition | 17894530 |
SM2219 |
CUGGCCUUUCACUACUCCUACGAGCAC GUGCUCGUAGGAGUAGUGAAAGGCCAG |
0 3-Amino |
0 27 |
0 Sugar |
41 percent target mRNA inhibition | 17894530 |
SM2220 |
CUGGCCUUUCACUACUCCUACGAGCAC GUGCUCGUAGGAGUAGUGAAAGGCCAG |
5-Amino 0 |
1 0 |
Sugar 0 |
76 percent target mRNA inhibition | 17894530 |
SM2221 |
CUGGCCUUUCACUACUCCUACGAGCAC GUGCUCGUAGGAGUAGUGAAAGGCCAG |
3-Amino 3-Amino |
27 27 |
Sugar Sugar |
36 percent target mRNA inhibition | 17894530 |
SM2222 |
CUGGCCUUUCACUACUCCUACGAGCAC GUGCUCGUAGGAGUAGUGAAAGGCCAG |
0 3-Amino |
0 27 |
0 Sugar |
68 percent target mRNA inhibition | 17894530 |
SM2223 |
CUGGCCUUUCACUACUCCUACGAGCAC GUGCUCGUAGGAGUAGUGAAAGGCCAG |
3-Amino 0 |
27 0 |
Sugar 0 |
72 percent target mRNA inhibition | 17894530 |
SM2224 |
CUGGCCUUUCACUACUCCUACGAGCAC GUGCUCGUAGGAGUAGUGAAAGGCCAG |
5-Amino 3-Amino |
1 27 |
Sugar Sugar |
70 percent target mRNA inhibition | 17894530 |
SM2225 |
CUGGCCUUUCACUACUCCUACGAGCAC GUGCUCGUAGGAGUAGUGAAAGGCCAG |
3-Amino 5-Amino |
27 1 |
Sugar Sugar |
77 percent target mRNA inhibition | 17894530 |
SM2226 |
CUGGCCUUUCACUACUCCUACGAGCAC GUGCUCGUAGGAGUAGUGAAAGGCCAG |
5-Thio 5-Thio |
1 1 |
Sugar Sugar |
81 percent target mRNA inhibition | 17894530 |
SM2227 |
CUGGCCUUUCACUACUCCUACGAGCAC GUGCUCGUAGGAGUAGUGAAAGGCCAG |
0 5-Thio |
0 1 |
0 Sugar |
86.5 percent target mRNA inhibition | 17894530 |
SM2228 |
CUGGCCUUUCACUACUCCUACGAGCAC GUGCUCGUAGGAGUAGUGAAAGGCCAG |
5-Thio 0 |
1 0 |
Sugar 0 |
94 percent target mRNA inhibition | 17894530 |
SM2229 |
CUGGCCUUUCACUACUCCUACGAGCAC GUGCUCGUAGGAGUAGUGAAAGGCCAG |
5-Cholesterol 0 |
1 0 |
Sugar 0 |
70 percent target mRNA inhibition | 17894530 |
SM2230 |
CUGGCCUUUCACUACUCCUACGAGCAC GUGCUCGUAGGAGUAGUGAAAGGCCAG |
5-Cholesterol 5-Amino |
1 1 |
Sugar Sugar |
56 percent target mRNA inhibition | 17894530 |
SM2231 |
CUGGCCUUUCACUACUCCUACGAGCAC GUGCUCGUAGGAGUAGUGAAAGGCCAG |
5-Cholesterol 3-Amino |
1 1 |
Sugar Sugar |
49 percent target mRNA inhibition | 17894530 |
SM2232 |
CUGGCCUUUCACUACUCCUACGAGCAC GUGCUCGUAGGAGUAGUGAAAGGCCAG |
5-Thio 5-Thio |
1 1 |
Sugar Sugar |
68 percent target mRNA inhibition | 17894530 |
SM2233 |
CUGGCCUUUCACUACUCCUACGAGCAC GUGCUCGUAGGAGUAGUGAAAGGCCAG |
0 5-Thio |
0 1 |
0 Sugar |
66 percent target mRNA inhibition | 17894530 |