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Note: (i) 0 indicates modification in opposite strand. (ii) Multiple modifications are separated bt asterisk (*).

• By modification in sense strand


• By modification position in sense strand


• By modification in antisense strand


• By modification position in antisense strand


• Reference
Total number of Results for 23344237 are 16
Results from 0 - 25


SMDBid	siRNA (sense/antisense) 5'>3'	Modification (sense/antisense)	Position (sense/antisense)	Modified component (sense/antisense)	Efficacy (%)	Reference
SM4839	GUCAUCACACUGAAUACCAAUUTT AAUUGGUAUUCAGUGUGAUGACTT	DeoxyThymidine DeoxyThymidine	23,24 23,24	Sugar Sugar	60 percent target mRNA inhibition	23344237
SM4840	GTCATCACACUGAAUACCAAUUTT AAUUGGUAUUCAGUGUGAUGACTT	2,4-bridged nucleic acid* DeoxyThymidine DeoxyThymidine	1,2,3,4,5 * 23,24 23,24	Sugar Sugar	NA	23344237
SM4841	GTCATCACACUGAATACCAAUUTT AAUUGGUAUUCAGUGUGAUGACTT	2,4-bridged nucleic acid* DeoxyThymidine DeoxyThymidine	1,2,5,15,18 * 23,24 23,24	Sugar Sugar	70 percent target mRNA inhibition	23344237
SM4842	GTCATCACACUGAATACCAAUUTT AAUUGGUAUUCAGUGUGAUGACTT	2,4-bridged nucleic acid* Phosphorothioate* DeoxyThymidine DeoxyThymidine	1,2,5,15,18 * 3,4,6,7,16,17,19,20,21,22 * 23,24 23,24	Sugar Sugar	50 percent target mRNA inhibition	23344237
SM4843	GTCATCACACUGAATACCAAUUTT AAUUGGUAUUCAGUGUGAUGACTT	2,4-bridged nucleic acid* Phosphorothioate* DeoxyThymidine* Cholesterol DeoxyThymidine	1,2,5,15,18 * 3,4,6,7,16,17,19,20,21,22 * 23,24 * 24 23,24	Sugar Sugar	20 percent target mRNA inhibition	23344237
SM4844	GTCATCACACUGAATACCAAUUTT AAUUGGUAUUCAGUGUGAUGACTT	2,4-bridged nucleic acid* Phosphorothioate* DeoxyThymidine* Cholesterol 2-Methoxyribose* DeoxyThymidine	1,2,5,15,18 * 3,4,6,7,16,17,19,20,21,22 * 23,24 * 24 13,15 * 23,24	Sugar Sugar	27 percent target mRNA inhibition	23344237
SM4845	GTCATCACACUGAATACCAAUUTT AAUUGGUAUUCAGTGTGAUGACTT	2,4-bridged nucleic acid* Phosphorothioate* DeoxyThymidine* Cholesterol 2,4-bridged nucleic acid* DeoxyThymidine	1,2,5,15,18 * 3,4,6,7,16,17,19,20,21,22 * 23,24 * 24 14,16* 23,24	Sugar Sugar	16 percent target mRNA inhibition	23344237
SM4846	GUCAUCACACUGAAUACCAAUUTT AAUUGGUAUUCAGUGUGAUGACTT	DeoxyThymidine* Cholesterol DeoxyThymidine	23,24 * 24 23,24	Sugar Sugar	NA	23344237
SM4847	GTCATCACACUGAATACCAAUUTT AAUUGGUAUUCAGUGUGAUGACTT	2,4-bridged nucleic acid* Phosphorothioate* DeoxyThymidine DeoxyThymidine	1,2,5,15,18 *3,4,6,7,16,17,19,20,21,22 * 23,24 13,15 * 23,24	Sugar Sugar	NA	23344237
SM4848	GUAUCUCUUCAUAGCCUUATT UAAGGCUAUGAAGAGAUACTT	DeoxyThymidine DeoxyThymidine	20,21 20,21	Sugar Sugar	NA	23344237
SM4849	GUCAUCACACUGAAUACCAAUUTT AAUUGGUAUUCAGUGUGAUGACTT	DeoxyThymidine DeoxyThymidine	23,24 23,24	Sugar Sugar	95 percent target mRNA inhibition	23344237
SM4850	GTCATCACACUGAATACCAAUUTT AAUUGGUAUUCAGUGUGAUGACTT	2,4-bridged nucleic acid* DeoxyThymidine DeoxyThymidine	1,2,5,15,18 * 23,24 23,24	Sugar Sugar	96 percent target mRNA inhibition	23344237
SM4851	GTCATCACACUGAATACCAAUUTT AAUUGGUAUUCAGUGUGAUGACTT	2,4-bridged nucleic acid* Phosphorothioate* DeoxyThymidine DeoxyThymidine	1,2,5,15,18 * 3,4,6,7,16,17,19,20,21,22 * 23,24 23,24	Sugar Sugar	78 percent target mRNA inhibition	23344237
SM4852	GTCATCACACUGAATACCAAUUTT AAUUGGUAUUCAGUGUGAUGACTT	2,4-bridged nucleic acid* Phosphorothioate* DeoxyThymidine* Cholesterol DeoxyThymidine	1,2,5,15,18 * 3,4,6,7,16,17,19,20,21,22 * 23,24 * 24 23,24	Sugar Sugar	75 percent target mRNA inhibition	23344237
SM4853	GTCATCACACUGAATACCAAUUTT AAUUGGUAUUCAGUGUGAUGACTT	2,4-bridged nucleic acid* Phosphorothioate* DeoxyThymidine* Cholesterol 2-Methoxyribose* DeoxyThymidine	1,2,5,15,18 * 3,4,6,7,16,17,19,20,21,22 * 23,24 * 24 13,15 * 23,24	Sugar Sugar	73 percent target mRNA inhibition	23344237
SM4854	GTCATCACACUGAATACCAAUUTT AAUUGGUAUUCAGTGTGAUGACTT	2,4-bridged nucleic acid* Phosphorothioate* DeoxyThymidine* Cholesterol 2,4-bridged nucleic acid* DeoxyThymidine	1,2,5,15,18 * 3,4,6,7,16,17,19,20,21,22 * 23,24 * 24 14,16* 23,24	Sugar Sugar	55 percent target mRNA inhibition	23344237