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Note: (i) 0 indicates modification in opposite strand. (ii) Multiple modifications are separated bt asterisk (*).

• By modification in sense strand


• By modification position in sense strand


• By modification in antisense strand


• By modification position in antisense strand


• Reference
Total number of Results for 23682837 are 19
Results from 0 - 25


SMDBid	siRNA (sense/antisense) 5'>3'	Modification (sense/antisense)	Position (sense/antisense)	Modified component (sense/antisense)	Efficacy (%)	Reference
SM2391	GCAACUCAUGGUUCAUGCUTT AGCAUGAACCAUGAGUUGCTT	2-Deoxythymidine 2-Deoxythymidine	0 20,21	Sugar Sugar	40 percent target mRNA inhibition	23682837
SM2392	GCAACUCAUGGUUCAUGCUTT AGCAUGAACCAUGAGUUGCTT	D-Isonucleoside adenosine* 2-Deoxythymidine 2-Deoxythymidine	8* 20,21 20,21	Base Sugar	89 percent target mRNA inhibition	23682837
SM2393	GCAACUCAUGGUUCAUGCUTT AGCAUGAACCAUGAGUUGCTT	L-Isonucleoside adenosine* 2-Deoxythymidine 2-Deoxythymidine	8* 20,21 20,21	Base Sugar	22 percent target mRNA inhibition	23682837
SM2394	GCAACUCAUGGUUCAUGCUTT AGCAUGAACCAUGAGUUGCTT	D-Isonucleoside uracil* 2-Deoxythymidine 2-Deoxythymidine	9* 20,21 20,21	Base Sugar	31 percent target mRNA inhibition	23682837
SM2395	GCAACUCAUGGUUCAUGCUTT AGCAUGAACCAUGAGUUGCTT	L-Isonucleoside uracil* 2-Deoxythymidine 2-Deoxythymidine	9* 20,21 20,21	Base Sugar	10 percent target mRNA inhibition	23682837
SM2396	GCAACUCAUGGUUCAUGCUTT AGCAUGAACCAUGAGUUGCTT	D-Isonucleoside adenosine* 2-Deoxythymidine 2-Deoxythymidine	15* 20,21 20,21	Base Sugar	0 percent target mRNA inhibition	23682837
SM2397	GCAACUCAUGGUUCAUGCUTT AGCAUGAACCAUGAGUUGCTT	L-Isonucleoside adenosine* 2-Deoxythymidine 2-Deoxythymidine	15* 20,21 20,21	Base Sugar	0 percent target mRNA inhibition	23682837
SM2398	GCAACUCAUGGUUCAUGCUTT AGCAUGAACCAUGAGUUGCTT	D-Isonucleoside-uracil* 2-Deoxythymidine 2-Deoxythymidine	19* 20,21 20,21	Base Sugar	0 percent target mRNA inhibition	23682837
SM2399	GCAACUCAUGGUUCAUGCUTT AGCAUGAACCAUGAGUUGCTT	L-Isonucleoside uracil* 2-Deoxythymidine 2-Deoxythymidine	19* 20,21 20,21	Base Sugar	0 percent target mRNA inhibition	23682837
SM2400	GCAACUCAUGGUUCAUGCUTT AGCAUGAACCAUGAGUUGCTT	2-Deoxythymidine D-Isonucleoside adenosine* 2-Deoxythymidine	20,21 1* 20,21	Sugar Nucleoside	63 percent target mRNA inhibition	23682837
SM2401	GCAACUCAUGGUUCAUGCUTT AGCAUGAACCAUGAGUUGCTT	2-Deoxythymidine L-Isonucleoside adenosine* 2-Deoxythymidine	20,21 1* 20,21	Sugar Nucleoside	63 percent target mRNA inhibition	23682837
SM2402	GCAACUCAUGGUUCAUGCUTT AGCAUGAACCAUGAGUUGCTT	2-Deoxythymidine D-Isonucleoside adenosine* 2-Deoxythymidine	20,21 4* 20,21	Sugar Nucleoside	31 percent target mRNA inhibition	23682837
SM2403	GCAACUCAUGGUUCAUGCUTT AGCAUGAACCAUGAGUUGCTT	2-Deoxythymidine L-Isonucleoside adenosine* 2-Deoxythymidine	20,21 4* 20,21	Sugar Nucleoside	40 percent target mRNA inhibition	23682837
SM2404	GCAACUCAUGGUUCAUGCUTT AGCAUGAACCAUGAGUUGCTT	2-Deoxythymidine D-Isonucleoside uracil* 2-Deoxythymidine	20,21 5* 20,21	Sugar Nucleoside	27 percent target mRNA inhibition	23682837
SM2405	GCAACUCAUGGUUCAUGCUTT AGCAUGAACCAUGAGUUGCTT	2-Deoxythymidine L-Isonucleoside uracil* 2-Deoxythymidine	20,21 5* 20,21	Sugar Nucleoside	0 percent target mRNA inhibition	23682837
SM2406	GCAACUCAUGGUUCAUGCUTT AGCAUGAACCAUGAGUUGCTT	2-Deoxythymidine D-Isonucleoside adenosine* 2-Deoxythymidine	20,21 11* 20,21	Sugar Nucleoside	4 percent target mRNA inhibition	23682837
SM2407	GCAACUCAUGGUUCAUGCUTT AGCAUGAACCAUGAGUUGCTT	2-Deoxythymidine L-Isonucleoside adenosine* 2-Deoxythymidine	20,21 11* 20,21	Sugar Nucleoside	29 percent target mRNA inhibition	23682837
SM2408	GCAACUCAUGGUUCAUGCUTT AGCAUGAACCAUGAGUUGCTT	2-Deoxythymidine D-Isonucleoside uracil* 2-Deoxythymidine	20,21 12* 20,21	Sugar Nucleoside	26 percent target mRNA inhibition	23682837
SM2409	GCAACUCAUGGUUCAUGCUTT AGCAUGAACCAUGAGUUGCTT	2-Deoxythymidine L-Isonucleoside uracil* 2-Deoxythymidine	20,21 12* 20,21	Sugar Nucleoside	0 percent target mRNA inhibition	23682837