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Note: (i) 0 indicates modification in opposite strand. (ii) Multiple modifications are separated bt asterisk (*).
  • By modification in sense strand

  • By modification position in sense strand

  • By modification in antisense strand

  • By modification position in antisense strand

  • Reference
    • Total number of Results for 0 are 558
    Results from 500 - 525
    SMDBidsiRNA (sense/antisense) 5'>3'Modification (sense/antisense)Position (sense/antisense) Modified component (sense/antisense) Efficacy (%)Reference
    SM4645
    GGCCUUUCACUACUCCUACGA
    GUAGGAGUAGUGAAAGGCCAG
    Lauric acid
    0
    1
    0
    Phosphate
    0
    0 percent target mRNA inhibition
    22494497
    SM4646
    GGCCUUUCACUACUCCUACGA
    GUAGGAGUAGUGAAAGGCCAG
    Cholesterol
    0
    1
    0
    Phosphate
    0
    0 percent target mRNA inhibition
    22494497
    SM4648
    CUGGCCUUUCACUACUCCUACGAGCAC
    GUGCUCGUAGGAGUAGUGAAAGGCCAG
    Palmitic acid
    0
    1
    0
    Phosphate
    0
    40 percent target mRNA inhibition
    22494497
    SM4649
    CUGGCCUUUCACUACUCCUACGAGCAC
    GUGCUCGUAGGAGUAGUGAAAGGCCAG
    Lauric acid
    0
    1
    0
    Phosphate
    0
    0 percent target mRNA inhibition
    22494497
    SM4650
    CUGGCCUUUCACUACUCCUACGAGCAC
    GUGCUCGUAGGAGUAGUGAAAGGCCAG
    Cholesterol
    0
    1
    0
    Phosphate
    0
    10 percent target mRNA inhibition
    22494497
    SM4652
    UCCUACAGCACAACAAAUGUG
    CAUUUGUUGUGCUGUAGGAAG
    Palmitic acid
    0
    1
    0
    Phosphate
    0
    85 percent target mRNA inhibition
    22494497
    SM4654
    CUUCCUACAGCACAACAAAUGUGAAUG
    CAUUCACAUUUGUUGUGCUGUAGGAAG
    Palmitic acid
    0
    1
    0
    Phosphate
    0
    95 percent target mRNA inhibition
    22494497
    SM4656
    UCCUACAGCACAACAAAUGUG
    CAUUUGUUGUGCUGUAGGAAG
    Palmitic acid
    0
    1
    0
    Phosphate
    0
    15 percent target mRNA inhibition
    22494497
    SM4658
    CUUCCUACAGCACAACAAAUGUGAAUG
    CAUUCACAUUUGUUGUGCUGUAGGAAG
    Palmitic acid
    0
    1
    0
    Phosphate
    0
    40 percent target mRNA inhibition
    22494497
    SM4683
    NNNNNNNNNNNNNNNNNNNNNN
    NNNNNNNNNNNNNNNNNNNNNN
    Locked nucleic acid
    0
    1,2,13,14
    0
    Sugar
    0
    80 percent target mRNA inhibition
    EP2548962A1
    SM4685
    NNNNNNNNNNNNNNNNNNNNNN
    NNNNNNNNNNNNNNNNNNNNNN
    Locked nucleic acid
    0
    1,2,10,14
    0
    Sugar
    0
    69 percent target mRNA inhibition
    EP2548962A1
    SM4689
    NNNNNNNNNNNNNNNNNNNNNN
    NNNNNNNNNNNNNNNNNNNNNN
    Locked nucleic acid
    0
    1,20,21
    0
    Sugar
    0
    0 percent target mRNA inhibition
    EP2548962A1
    SM4692
    NNNNNNNNNNNNNNNNNNNNNN
    NNNNNNNNNNNNNNNNNNNNNN
    Locked nucleic acid
    0
    1,2,13,14
    0
    Sugar
    0
    0 percent target mRNA inhibition
    EP2548962A1
    SM4694
    NNNNNNNNNNNNNNNNNNNNNN
    NNNNNNNNNNNNNNNNNNNNNN
    Locked nucleic acid
    0
    1,2,10,14
    0
    Sugar
    0
    0 percent target mRNA inhibition
    EP2548962A1
    SM4696
    NNNNNNNNNNNNNNNNNNNNNN
    NNNNNNNNNNNNNNNNNNNNNN
    Locked nucleic acid
    0
    1,2
    0
    Sugar
    0
    0 percent target mRNA inhibition
    EP2548962A1
    SM4697
    NNNNNNNNNNNNNNNNNNNNNN
    NNNNNNNNNNNNNNNNNNNNNN
    2-O-Methyl
    0
    1,2,12,13
    0
    Sugar
    0
    70 percent target mRNA inhibition
    EP2548962A1
    SM4698
    NNNNNNNNNNNNNNNNNNNNNN
    NNNNNNNNNNNNNNNNNNNNNN
    2-O-Methyl
    0
    1,2,13,14
    0
    Sugar
    0
    75 percent target mRNA inhibition
    EP2548962A1
    SM4699
    NNNNNNNNNNNNNNNNNNNNNN
    NNNNNNNNNNNNNNNNNNNNNN
    2-O-Methyl
    0
    1,2,14,15
    0
    Sugar
    0
    70 percent target mRNA inhibition
    EP2548962A1
    SM4700
    NNNNNNNNNNNNNNNNNNNNNN
    NNNNNNNNNNNNNNNNNNNNNN
    2-O-Methyl
    0
    1,2,10,12
    0
    Sugar
    0
    70 percent target mRNA inhibition
    EP2548962A1
    SM4701
    NNNNNNNNNNNNNNNNNNNNNN
    NNNNNNNNNNNNNNNNNNNNNN
    2-O-Methyl
    0
    1,2,10,14
    0
    Sugar
    0
    70 percent target mRNA inhibition
    EP2548962A1
    SM4703
    NNNNNNNNNNNNNNNNNNNNNN
    NNNNNNNNNNNNNNNNNNNNNN
    2-O-Methyl
    0
    1,2,12,13
    0
    Sugar
    0
    0 percent target mRNA inhibition
    EP2548962A1
    SM4704
    NNNNNNNNNNNNNNNNNNNNNN
    NNNNNNNNNNNNNNNNNNNNNN
    2-O-Methyl
    0
    1,2,13,14
    0
    Sugar
    0
    0 percent target mRNA inhibition
    EP2548962A1
    SM4705
    NNNNNNNNNNNNNNNNNNNNNN
    NNNNNNNNNNNNNNNNNNNNNN
    2-O-Methyl
    0
    1,2,14,15
    0
    Sugar
    0
    0 percent target mRNA inhibition
    EP2548962A1
    SM4706
    NNNNNNNNNNNNNNNNNNNNNN
    NNNNNNNNNNNNNNNNNNNNNN
    2-O-Methyl
    0
    1,2,10,12
    0
    Sugar
    0
    0 percent target mRNA inhibition
    EP2548962A1
    SM4707
    NNNNNNNNNNNNNNNNNNNNNN
    NNNNNNNNNNNNNNNNNNNNNN
    2-O-Methyl
    0
    1,2,10,14
    0
    Sugar
    0
    0 percent target mRNA inhibition
    EP2548962A1