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Note: (i) 0 indicates modification in opposite strand. (ii) Multiple modifications are separated bt asterisk (*).
  • By modification in sense strand

  • By modification position in sense strand

  • By modification in antisense strand

  • By modification position in antisense strand

  • Reference
  • Total number of Results for Peptide nucleic acids are 8
    Results from 0 - 25
    SMDBidsiRNA (sense/antisense) 5'>3'Modification (sense/antisense)Position (sense/antisense) Modified component (sense/antisense) Efficacy (%)Reference
    SM2659
    UCGAAGUAUUCCGCGUACGTT
    CGUACGCGGAAUACUUCGATT
    Peptide nucleic acids
    0
    21
    0
    Phosphate
    0
    82 percent target mRNA inhibition
    19325750
    SM2661
    UCGAAGUAUUCCGCGUACGTT
    CGUACGCGGAAUACUUCGATT
    Peptide nucleic acids
    Peptide nucleic acids
    21
    21
    Phosphate
    Phosphate
    81 percent target mRNA inhibition
    19325750
    SM2663
    UCGAAGUAUUCCGCGUACGTT
    CGUACGCGGAAUACUUCGATT
    Peptide nucleic acids
    0
    21
    0
    Phosphate
    0
    80 percent target mRNA inhibition
    19325750
    SM2665
    UCGAAGUAUUCCGCGUACGTT
    CGUACGCGGAAUACUUCGATT
    Peptide nucleic acids
    Peptide nucleic acids
    21
    21
    Phosphate
    Phosphate
    75 percent target mRNA inhibition
    19325750
    SM2667
    UCGAAGUAUUCCGCGUACGTT
    CGUACGCGGAAUACUUCGATT
    Peptide nucleic acids
    0
    21
    0
    Phosphate
    0
    80 percent target mRNA inhibition
    19325750
    SM2669
    UCGAAGUAUUCCGCGUACGTT
    CGUACGCGGAAUACUUCGATT
    Peptide nucleic acids
    Peptide nucleic acids
    21
    21
    Phosphate
    Phosphate
    80 percent target mRNA inhibition
    19325750
    SM2671
    UCGAAGUAUUCCGCGUACGTT
    CGUACGCGGAAUACUUCGATT
    Peptide nucleic acids
    0
    21
    0
    Phosphate
    0
    70 percent target mRNA inhibition
    19325750
    SM2673
    UCGAAGUAUUCCGCGUACGTT
    CGUACGCGGAAUACUUCGATT
    Peptide nucleic acids
    Peptide nucleic acids
    21
    21
    Phosphate
    Phosphate
    56 percent target mRNA inhibition
    19325750