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Note: (i) 0 indicates modification in opposite strand. (ii) Multiple modifications are separated bt asterisk (*).
  • By modification in sense strand

  • By modification position in sense strand

  • By modification in antisense strand

  • By modification position in antisense strand

  • Reference
    • Total number of Results for Tricyclodeoxyribonucleic acid are 27
    Results from 0 - 25
    SMDBidsiRNA (sense/antisense) 5'>3'Modification (sense/antisense)Position (sense/antisense) Modified component (sense/antisense) Efficacy (%)Reference
    SM3231
    GCAGCACGACUUCUUCAAGTT
    CUUGAAGAAGUCGUGCUGCTT
    Tricyclodeoxyribonucleic acid
    0
    20,21
    0
    Sugar
    0
    90 percent target mRNA inhibition
    18776474
    SM3232
    GCAGCACGACUUCTTCAAGTT
    CUUGAAGAAGUCGUGCUGCTT
    Tricyclodeoxyribonucleic acid
    0
    13,14,15,16,20,21
    0
    Sugar
    0
    90 percent target mRNA inhibition
    18776474
    SM3233
    GCAGCACGACUUCUUCAAGTT
    CUUGAAGAAGUCGUGCUGCTT
    Tricyclodeoxyribonucleic acid
    0
    2,5,7,20,21
    0
    Sugar
    0
    79 percent target mRNA inhibition
    18776474
    SM3236
    GCAGCACGACUUCUUCAAGTT
    CUUGAAGAAGUCGUGCUGCTT
    Tricyclodeoxyribonucleic acid
    0
    20,21
    0
    Sugar
    0
    85 percent target mRNA inhibition
    21687522
    SM3237
    GCAGCACGACUUCUUCAAGTT
    CUUGAAGAAGUCGUGCUGCTT
    Tricyclodeoxyribonucleic acid
    0
    10,20,21
    0
    Sugar
    0
    86 percent target mRNA inhibition
    21687522
    SM3238
    GCAGCACGACUUCTTCAAGTT
    CUUGAAGAAGUCGUGCUGCTT
    Tricyclodeoxyribonucleic acid
    0
    13,14,15,16,20,21
    0
    Sugar
    0
    76 percent target mRNA inhibition
    21687522
    SM3239
    GCAGCACGACUUCUUCAAGTT
    CUUGAAGAAGUCGUGCUGCTT
    Tricyclodeoxyribonucleic acid
    0
    2,5,7,20,21
    0
    Sugar
    0
    90 percent target mRNA inhibition
    21687522
    SM3244
    GCAGCACGACUUCUUCAAGTT
    CUUGAAGAAGUCGUGCUGCTT
    Tricyclodeoxyribonucleic acid
    Tricyclodeoxyribonucleic acid
    20,21
    20,21
    Sugar
    Sugar
    81 percent target mRNA inhibition
    21687522
    SM3245
    GCAGCACGACUUCUUCAAGTT
    CUUGAAGAAGTCGUGCUGCTT
    Tricyclodeoxyribonucleic acid
    Tricyclodeoxyribonucleic acid
    10,20,21
    11,20,21
    Sugar
    Sugar
    88 percent target mRNA inhibition
    21687522
    SM3246
    GCAGCACGACUUCTTCAAGTT
    CUUGAAGAAGTCGUGCUGCTT
    Tricyclodeoxyribonucleic acid
    Tricyclodeoxyribonucleic acid
    13,14,15,16,20,21
    11,20,21
    Sugar
    Sugar
    89 percent target mRNA inhibition
    21687522
    SM3247
    GCAGCACGACUUCTTCAAGTT
    CUUGAAGAAGUCGUGCTGCTT
    Tricyclodeoxyribonucleic acid
    Tricyclodeoxyribonucleic acid
    13,14,15,16,20,21
    16,17,19,20,21
    Sugar
    Sugar
    23 percent target mRNA inhibition
    21687522
    SM3250
    GCAGCACGACUUCUUCAAGTT
    CUUGAAGAAGUCGUGCUGCTT
    Tricyclodeoxyribonucleic acid
    0
    20,21
    0
    Sugar
    0
    73 percent target mRNA inhibition
    21687522
    SM3251
    GCAGCACGACUUCUUCAAGTT
    CUUGAAGAAGUCGUGCUGCTT
    Tricyclodeoxyribonucleic acid
    0
    10,20,21
    0
    Sugar
    0
    72 percent target mRNA inhibition
    21687522
    SM3252
    GCAGCACGACUUCTTCAAGTT
    CUUGAAGAAGUCGUGCUGCTT
    Tricyclodeoxyribonucleic acid
    0
    13,14,15,16,20,21
    0
    Sugar
    0
    84 percent target mRNA inhibition
    21687522
    SM3253
    GCAGCACGACUUCUUCAAGTT
    CUUGAAGAAGUCGUGCUGCTT
    Tricyclodeoxyribonucleic acid
    0
    2,5,7,20,21
    0
    Sugar
    0
    57 percent target mRNA inhibition
    21687522
    SM3258
    GCAGCACGACUUCUUCAAGTT
    CUUGAAGAAGUCGUGCUGCTT
    Tricyclodeoxyribonucleic acid
    Tricyclodeoxyribonucleic acid
    20,21
    20,21
    Sugar
    Sugar
    71 percent target mRNA inhibition
    21687522
    SM3259
    GCAGCACGACUUCUUCAAGTT
    CUUGAAGAAGTCGUGCUGCTT
    Tricyclodeoxyribonucleic acid
    Tricyclodeoxyribonucleic acid
    10,20,21
    11,20,21
    Sugar
    Sugar
    85 percent target mRNA inhibition
    21687522
    SM3260
    GCAGCACGACUUCTTCAAGTT
    CUUGAAGAAGTCGUGCUGCTT
    Tricyclodeoxyribonucleic acid
    Tricyclodeoxyribonucleic acid
    13,14,15,16,20,21
    11,20,21
    Sugar
    Sugar
    86 percent target mRNA inhibition
    21687522
    SM3261
    GCAGCACGACUUCTTCAAGTT
    CUUGAAGAAGUCGUGCTGCTT
    Tricyclodeoxyribonucleic acid
    Tricyclodeoxyribonucleic acid
    13,14,15,16,20,21
    16,17,19,20,21
    Sugar
    Sugar
    6 percent target mRNA inhibition
    21687522
    SM3264
    GCAGCACGACUUCUUCAAGTT
    CUUGAAGAAGUCGUGCUGCTT
    Tricyclodeoxyribonucleic acid
    0
    20,21
    0
    Sugar
    0
    48 percent target mRNA inhibition
    21687522
    SM3265
    GCAGCACGACUUCUUCAAGTT
    CUUGAAGAAGUCGUGCUGCTT
    Tricyclodeoxyribonucleic acid
    0
    10,20,21
    0
    Sugar
    0
    49 percent target mRNA inhibition
    21687522
    SM3266
    GCAGCACGACUUCTTCAAGTT
    CUUGAAGAAGUCGUGCUGCTT
    Tricyclodeoxyribonucleic acid
    0
    13,14,15,16,20,21
    0
    Sugar
    0
    67 percent target mRNA inhibition
    21687522
    SM3267
    GCAGCACGACUUCUUCAAGTT
    CUUGAAGAAGUCGUGCUGCTT
    Tricyclodeoxyribonucleic acid
    0
    2,5,7,20,21
    0
    Sugar
    0
    39 percent target mRNA inhibition
    21687522
    SM3272
    GCAGCACGACUUCUUCAAGTT
    CUUGAAGAAGUCGUGCUGCTT
    Tricyclodeoxyribonucleic acid
    Tricyclodeoxyribonucleic acid
    20,21
    20,21
    Sugar
    Sugar
    51 percent target mRNA inhibition
    21687522
    SM3273
    GCAGCACGACUUCUUCAAGTT
    CUUGAAGAAGTCGUGCUGCTT
    Tricyclodeoxyribonucleic acid
    Tricyclodeoxyribonucleic acid
    10,20,21
    11,20,21
    Sugar
    Sugar
    80 percent target mRNA inhibition
    21687522