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Note: (i) 0 indicates modification in opposite strand. (ii) Multiple modifications are separated bt asterisk (*).
  • By modification in sense strand

  • By modification position in sense strand

  • By modification in antisense strand

  • By modification position in antisense strand

  • Reference
    • Total number of Results for 0 are 634
    Results from 350 - 375
    SMDBidsiRNA (sense/antisense) 5'>3'Modification (sense/antisense)Position (sense/antisense) Modified component (sense/antisense) Efficacy (%)Reference
    SM3188
    ACCCUGAAGUUCAUCUGCACCACCG
    CGGUGGUGCAGAUGAACUUCAGGGUCA
    0
    2-O-Methyl
    0
    1,2,9,11,13,15,17,19,21,23,25,26,27
    0
    Sugar
    15 percent target mRNA inhibition
    18637735
    SM3192
    ACCCUGAAGUUCAUCUGCACCACCG
    CGGUGGUGCAGAUGAACUUCAGGGUCA
    0
    2-O-Methyl
    0
    9,11,13,15,17,19,21,23,25,26,27
    0
    Sugar
    95 percent target mRNA inhibition
    18637735
    SM3194
    ACCCUGAAGUUCAUCUGCACCACCG
    CGGUGGUGCAGAUGAACUUCAGGGUCA
    0
    2-O-Methyl
    0
    1,2,9,11,13,15,17,19,21,23,25,26,27
    0
    Sugar
    90 percent target mRNA inhibition
    18637735
    SM3198
    ACCCUGAAGUUCAUCUGCACCACCG
    CGGUGGUGCAGAUGAACUUCAGGGUCA
    0
    2-O-Methyl
    0
    9,11,13,15,17,19,21,23,25,26,27
    0
    Sugar
    97 percent target mRNA inhibition
    18637735
    SM3200
    ACCCUGAAGUUCAUCUGCACCACCG
    CGGUGGUGCAGAUGAACUUCAGGGUCA
    0
    2-O-Methyl
    0
    1,2,9,11,13,15,17,19,21,23,25,26,27
    0
    Sugar
    95 percent target mRNA inhibition
    18637735
    SM3203
    GCCAGACUUUGUUGGAUUUUGAAATT
    AAUUUCAAAUCCAACAAAGUCUGGCUU
    0
    2-O-Methyl
    0
    9,11,13,15,17,19,21,23,25,26,27
    0
    Sugar
    73 percent target mRNA inhibition
    18637735
    SM3204
    GCCAGACUUUGUUGGAUUUUGAAATT
    AAUUUCAAAUCCAACAAAGUCUGGCUU
    0
    2-O-Methyl
    0
    9,11,13,15,17,19,21,23,25,26,27
    0
    Sugar
    60 percent target mRNA inhibition
    18637735
    SM3206
    GCCAGACUUUGUUGGAUUUUGAAATT
    AAUUUCAAAUCCAACAAAGUCUGGCUU
    0
    2-O-Methyl
    0
    9,11,13,15,17,19,21,23,25,26,27
    0
    Sugar
    90 percent target mRNA inhibition
    18637735
    SM3207
    GCCAGACUUUGUUGGAUUUUGAAATT
    AAUUUCAAAUCCAACAAAGUCUGGCUU
    0
    2-O-Methyl
    0
    9,11,13,15,17,19,21,23,25,26,27
    0
    Sugar
    13 percent target mRNA inhibition
    18637735
    SM3209
    GCCAGACUUUGUUGGAUUUUGAAATT
    AAUUUCAAAUCCAACAAAGUCUGGCUU
    0
    2-O-Methyl
    0
    9,11,13,15,17,19,21,23,25,26,27
    0
    Sugar
    95 percent target mRNA inhibition
    18637735
    SM3210
    GCCAGACUUUGUUGGAUUUUGAAATT
    AAUUUCAAAUCCAACAAAGUCUGGCUU
    0
    2-O-Methyl
    0
    9,11,13,15,17,19,21,23,25,26,27
    0
    Sugar
    94 percent target mRNA inhibition
    18637735
    SM3212
    GCCAGUAAUUCAGCAGUUUGAACAA
    UUGUUCAAACUGCUGAAUUACUGGCUG
    0
    2-O-Methyl
    0
    9,11,13,15,17,19,21,23,25,26,27
    0
    Sugar
    44 percent target mRNA inhibition
    18637735
    SM3214
    CACCAAUGAAUUCUCGAUUGAUGTG
    CACAUCAAUCGAGAAUUCAUUGGUGUU
    0
    2-O-Methyl
    0
    11,13,15,17,19,21,23,25,26,27
    0
    Sugar
    NA
    18637735
    SM3216
    GCAUUCCAGAGAAAGCGUUUAAUTT
    AAAUUAAACGCUUUCUCUGGAAUGCCU
    0
    2-O-Methyl
    0
    11,13,15,17,19,21,23,25,26,27
    0
    Sugar
    41 percent target mRNA inhibition
    18637735
    SM3218
    GCCAGUAAUUCAGCAGUUUGAACAA
    UUGUUCAAACUGCUGAAUUACUGGCUG
    0
    2-O-Methyl
    0
    9,11,13,15,17,19,21,23,25,26,27
    0
    Sugar
    75 percent target mRNA inhibition
    18637735
    SM3220
    CACCAAUGAAUUCUCGAUUGAUGTG
    CACAUCAAUCGAGAAUUCAUUGGUGUU
    0
    2-O-Methyl
    0
    11,13,15,17,19,21,23,25,26,27
    0
    Sugar
    NA
    18637735
    SM3222
    GCAUUCCAGAGAAAGCGUUUAAUTT
    AAAUUAAACGCUUUCUCUGGAAUGCCU
    0
    2-O-Methyl
    0
    11,13,15,17,19,21,23,25,26,27
    0
    Sugar
    76 percent target mRNA inhibition
    18637735
    SM3224
    GCCAGUAAUUCAGCAGUUUGAACAA
    UUGUUCAAACUGCUGAAUUACUGGCUG
    0
    2-O-Methyl
    0
    9,11,13,15,17,19,21,23,25,26,27
    0
    Sugar
    85 percent target mRNA inhibition
    18637735
    SM3226
    CACCAAUGAAUUCUCGAUUGAUGTG
    CACAUCAAUCGAGAAUUCAUUGGUGUU
    0
    2-O-Methyl
    0
    11,13,15,17,19,21,23,25,26,27
    0
    Sugar
    NA
    18637735
    SM3228
    GCAUUCCAGAGAAAGCGUUUAAUTT
    AAAUUAAACGCUUUCUCUGGAAUGCCU
    0
    2-O-Methyl
    0
    11,13,15,17,19,21,23,25,26,27
    0
    Sugar
    83 percent target mRNA inhibition
    18637735
    SM3240
    GCAGCACGACUUCUUCAAGTT
    CUUGAAGAAGUCGUGCUGCTT
    0
    Tricyclodeoxyribonucleic acid
    0
    20,21
    0
    Sugar
    79 percent target mRNA inhibition
    21687522
    SM3241
    GCAGCACGACUUCUUCAAGTT
    CUUGAAGAAGTCGUGCUGCTT
    0
    Tricyclodeoxyribonucleic acid
    0
    11,20,21
    0
    Sugar
    88 percent target mRNA inhibition
    21687522
    SM3242
    GCAGCACGACUUCUUCAAGTT
    CUUGAAGAAGUCGUGCTGCTT
    0
    Tricyclodeoxyribonucleic acid
    0
    16,17,19,20,21
    0
    Sugar
    25 percent target mRNA inhibition
    21687522
    SM3243
    GCAGCACGACUUCUUCAAGTT
    CTTGAAGAAGUCGUGCUGCTT
    0
    Tricyclodeoxyribonucleic acid
    0
    1,2,3,20,21
    0
    Sugar
    12 percent target mRNA inhibition
    21687522
    SM3254
    GCAGCACGACUUCUUCAAGTT
    CUUGAAGAAGUCGUGCUGCTT
    0
    Tricyclodeoxyribonucleic acid
    0
    20,21
    0
    Sugar
    70 percent target mRNA inhibition
    21687522