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Note: (i) 0 indicates modification in opposite strand. (ii) Multiple modifications are separated bt asterisk (*).
  • By modification in sense strand

  • By modification position in sense strand

  • By modification in antisense strand

  • By modification position in antisense strand

  • Reference
    • Total number of Results for 0 are 634
    Results from 325 - 350
    SMDBidsiRNA (sense/antisense) 5'>3'Modification (sense/antisense)Position (sense/antisense) Modified component (sense/antisense) Efficacy (%)Reference
    SM3117
    ACCUGACGUUGUACAAAUUTT
    AAUUUGUACAACGUCAGGUTT
    0
    2,4-Difluorobenzene
    0
    3
    0
    Base
    54 percent target mRNA inhibition
    18624291
    SM3118
    ACCUGACGUUGUACAAAUUTT
    AAUUUGUACAACGUCAGGUTT
    0
    2,4-Difluorobenzene
    0
    4
    0
    Base
    45 percent target mRNA inhibition
    18624291
    SM3119
    ACCUGACGUUGUACAAAUUTT
    AAUUUGUACAACGUCAGGUTT
    0
    2,4-Difluorobenzene
    0
    5
    0
    Base
    26 percent target mRNA inhibition
    18624291
    SM3120
    ACCUGACGUUGUACAAAUUTT
    AAUUUGUACAACGUCAGGUTT
    0
    2,4-Difluorobenzene
    0
    7
    0
    Base
    55 percent target mRNA inhibition
    18624291
    SM3121
    ACCUGACGUUGUACAAAUUTT
    AAUUUGUACAACGUCAGGUTT
    0
    4-Methylbenzimidazole
    0
    8
    0
    Base
    0 percent target mRNA inhibition
    18624291
    SM3122
    ACCUGACGUUGUACAAAUUTT
    AAUUUGUACAACGUCAGGUTT
    0
    4-Methylbenzimidazole
    0
    10
    0
    Base
    0 percent target mRNA inhibition
    18624291
    SM3123
    ACCUGACGUUGUACAAAUUTT
    AAUUUGUACAACGUCAGGUTT
    0
    4-Methylbenzimidazole
    0
    11
    0
    Base
    0 percent target mRNA inhibition
    18624291
    SM3124
    ACCUGACGUUGUACAAAUUTT
    AAUUUGUACAACGUCAGGUTT
    0
    4-Methylbenzimidazole
    0
    16
    0
    Base
    0 percent target mRNA inhibition
    18624291
    SM3125
    ACCUGACGUUGUACAAAUUTT
    AAUUUGUACAACGUCAGGUTT
    0
    2,4-Difluorobenzene
    0
    19
    0
    Base
    88 percent target mRNA inhibition
    18624291
    SM3131
    GCACCAGAGCCAAUGGAACUUGATG
    CAUCAAGUUCCAUUGGCUCUGGUGCUU
    0
    2-O-Methyl
    0
    9,11,13,15,17,19,21,23,25,26,27
    0
    Sugar
    95 percent target mRNA inhibition
    18637735
    SM3133
    GCACCAGAGCCAAUGGAACUUGATG
    CAUCAAGUUCCAUUGGCUCUGGUGCUU
    0
    2-O-Methyl
    0
    7,9,11,13,15,17,19,21,23,25
    0
    Sugar
    92 percent target mRNA inhibition
    18637735
    SM3137
    GCACCAGAGCCAAUGGAACUUGATG
    CAUCAAGUUCCAUUGGCUCUGGUGCUU
    0
    2-O-Methyl
    0
    12,15,16,21,22,24
    0
    Sugar
    88 percent target mRNA inhibition
    18637735
    SM3140
    GCACCAGAGCCAAUGGAACUUGATG
    CAUCAAGUUCCAUUGGCUCUGGUGCUU
    0
    2-Fluoro
    0
    8,9,10,11,13,14,17,18,19,20,23,25,26
    0
    Sugar
    85 percent target mRNA inhibition
    18637735
    SM3144
    GCACCAGAGCCAAUGGAACUUGATG
    CAUCAAGUUCCAUUGGCUCUGGUGCUU
    0
    2-Fluoro* 2-O-Methyl
    0
    8,9,10,11,13,14,17,18,19,20,23,25,26 * 12,15,16,21,22,24
    0
    Sugar
    79 percent target mRNA inhibition
    18637735
    SM3149
    GCACCAGAGCCAAUGGAACUUGATG
    CAUCAAGUUCCAUUGGCUCUGGUGCUU
    0
    2-O-Methyl
    0
    9,11,13,15,17,19,21,23,25,26,27
    0
    Sugar
    91 percent target mRNA inhibition
    18637735
    SM3151
    GCACCAGAGCCAAUGGAACUUGATG
    CAUCAAGUUCCAUUGGCUCUGGUGCUU
    0
    2-O-Methyl
    0
    7,9,11,13,15,17,19,21,23,25
    0
    Sugar
    89 percent target mRNA inhibition
    18637735
    SM3155
    GCACCAGAGCCAAUGGAACUUGATG
    CAUCAAGUUCCAUUGGCUCUGGUGCUU
    0
    2-O-Methyl
    0
    12,15,16,21,22,24
    0
    Sugar
    90 percent target mRNA inhibition
    18637735
    SM3158
    GCACCAGAGCCAAUGGAACUUGATG
    CAUCAAGUUCCAUUGGCUCUGGUGCUU
    0
    2-Fluoro
    0
    8,9,10,11,13,14,17,18,19,20,23,25,26
    0
    Sugar
    88 percent target mRNA inhibition
    18637735
    SM3162
    GCACCAGAGCCAAUGGAACUUGATG
    CAUCAAGUUCCAUUGGCUCUGGUGCUU
    0
    2-Fluoro* 2-O-Methyl
    0
    8,9,10,11,13,14,17,18,19,20,23,25,26 * 12,15,16,21,22,24
    0
    Sugar
    68 percent target mRNA inhibition
    18637735
    SM3167
    GCACCAGAGCCAAUGGAACUUGATG
    CAUCAAGUUCCAUUGGCUCUGGUGCUU
    0
    2-O-Methyl
    0
    9,11,13,15,17,19,21,23,25,26,27
    0
    Sugar
    62 percent target mRNA inhibition
    18637735
    SM3169
    GCACCAGAGCCAAUGGAACUUGATG
    CAUCAAGUUCCAUUGGCUCUGGUGCUU
    0
    2-O-Methyl
    0
    7,9,11,13,15,17,19,21,23,25
    0
    Sugar
    45 percent target mRNA inhibition
    18637735
    SM3173
    GCACCAGAGCCAAUGGAACUUGATG
    CAUCAAGUUCCAUUGGCUCUGGUGCUU
    0
    2-O-Methyl
    0
    12,15,16,21,22,24
    0
    Sugar
    45 percent target mRNA inhibition
    18637735
    SM3176
    GCACCAGAGCCAAUGGAACUUGATG
    CAUCAAGUUCCAUUGGCUCUGGUGCUU
    0
    2-Fluoro
    0
    8,9,10,11,13,14,17,18,19,20,23,25,26
    0
    Sugar
    14 percent target mRNA inhibition
    18637735
    SM3180
    GCACCAGAGCCAAUGGAACUUGATG
    CAUCAAGUUCCAUUGGCUCUGGUGCUU
    0
    2-Fluoro* 2-O-Methyl
    0
    8,9,10,11,13,14,17,18,19,20,23,25,26 * 12,15,16,21,22,24
    0
    Sugar
    0 percent target mRNA inhibition
    18637735
    SM3186
    ACCCUGAAGUUCAUCUGCACCACCG
    CGGUGGUGCAGAUGAACUUCAGGGUCA
    0
    2-O-Methyl
    0
    9,11,13,15,17,19,21,23,25,26,27
    0
    Sugar
    29 percent target mRNA inhibition
    18637735