SMDBid | siRNA (sense/antisense) 5'>3' | Modification (sense/antisense) | Position (sense/antisense) |
Modified component (sense/antisense) |
Efficacy (%) | Reference |
SM3017 |
GUUCACCUUGAUGCCGUUCUU GAACGGCAUCAAGGUGAACUU |
Phosphorothioate 0 |
4,6,7,14,15,19 0 |
Phosphate 0 |
85 percent target mRNA inhibition | 15545637 |
SM3018 |
GUUCACCUUGAUGCCGUUCUU GAACGGCAUCAAGGUGAACUU |
Boranophosphate 0 |
4,6,7,14,15,19 0 |
Phosphate 0 |
98 percent target mRNA inhibition | 15545637 |
SM3019 |
GUUCACCUUGAUGCCGUUCUU GAACGGCAUCAAGGUGAACUU |
Phosphorothioate 0 |
2,3,8,9,12,17,18,20,21 0 |
Phosphate 0 |
45 percent target mRNA inhibition | 15545637 |
SM3020 |
GUUCACCUUGAUGCCGUUCUU GAACGGCAUCAAGGUGAACUU |
Boranophosphate 0 |
2,3,8,9,12,17,18,20,21 0 |
Phosphate 0 |
70 percent target mRNA inhibition | 15545637 |
SM3021 |
GUUCACCUUGAUGCCGUUCUU GAACGGCAUCAAGGUGAACUU |
0 Phosphorothioate |
0 4,7,10,19 |
0 Phosphate |
58 percent target mRNA inhibition | 15545637 |
SM3022 |
GUUCACCUUGAUGCCGUUCUU GAACGGCAUCAAGGUGAACUU |
0 Boranophosphate |
0 4,7,10,19 |
0 Phosphate |
91 percent target mRNA inhibition | 15545637 |
SM3023 |
GUUCACCUUGAUGCCGUUCUU GAACGGCAUCAAGGUGAACUU |
0 Phosphorothioate |
0 9,15,20,21 |
0 Phosphate |
63 percent target mRNA inhibition | 15545637 |
SM3024 |
GUUCACCUUGAUGCCGUUCUU GAACGGCAUCAAGGUGAACUU |
0 Boranophosphate |
0 9,15,20,21 |
0 Phosphate |
81 percent target mRNA inhibition | 15545637 |
SM3025 |
GUUCACCUUGAUGCCGUUCUU GAACGGCAUCAAGGUGAACUU |
Boranophosphate Boranophosphate |
4,6,7,14,15,19 4,7,10,19 |
Phosphate Phosphate |
90 percent target mRNA inhibition | 15545637 |
SM3026 |
GUUCACCUUGAUGCCGUUCUU GAACGGCAUCAAGGUGAACUU |
Boranophosphate Boranophosphate |
2,3,4,6,7,8,9,12,14,15,17,18,19,20,21 4,7,9,10,15,19,20,21 |
Phosphate Phosphate |
45 percent target mRNA inhibition | 15545637 |
SM3027 |
GUUCACCUUGAUGCCGUUCUU GAACGGCAUCAAGGUGAACUU |
Boranophosphate Boranophosphate |
4,5,6,7,11,14,15,19 2,3,4,7,8,10,11,12,17,18,19 |
Phosphate Phosphate |
89 percent target mRNA inhibition | 15545637 |
SM3028 |
GUUCACCUUGAUGCCGUUCUU GAACGGCAUCAAGGUGAACUU |
Boranophosphate Boranophosphate |
2,3,4,5,6,7,8,9,11,12,14,15,17,18,19,20,21 4,7,10,19 |
Phosphate Phosphate |
52 percent target mRNA inhibition | 15545637 |
SM3029 |
GUUCACCUUGAUGCCGUUCUU GAACGGCAUCAAGGUGAACUU |
Boranophosphate Boranophosphate |
4,6,7,14,15,19 2,3,4,7,8,9,10,11,12,15,17,18,19,20,21 |
Phosphate Phosphate |
82 percent target mRNA inhibition | 15545637 |
SM3030 |
GUUCACCUUGAUGCCGUUCUU GAACGGCAUCAAGGUGAACUU |
Boranophosphate Boranophosphate |
2,3,4,5,6,7,8,9,11,12,14,15,17,18,19,20,21 2,3,4,7,8,9,10,11,12,15,17,18,19,20,21 |
Phosphate Phosphate |
61 percent target mRNA inhibition | 15545637 |
SM3034 |
GUUCACCUUGAUGCCGUUCUU GCACGACUUCUUCAAGUCCUU |
Boranophosphate 0 |
3,8,9,11,12 0 |
Phosphate 0 |
58 percent target mRNA inhibition | 15545637 |
SM3035 |
GUUCACCUUGAUGCCGUUCUU GCACGACUUCUUCAAGUCCUU |
Boranophosphate 0 |
5,6,14,20,21 0 |
Phosphate 0 |
73 percent target mRNA inhibition | 15545637 |